Values CatLog read from this paper
Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry
PMID 26859324doi:10.1021/acs.biochem.5b01378Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (11 values) from this paper: cyclooxygenase-2 (COX-2) from Homo sapiens, Mus musculus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 5 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cyclooxygenase-2 (COX-2) | Homo sapiens | arachidonic acidPOPC nanodiscs | 39.7 | 0.0122 | 3.25 × 10³ calc. | Open record: cyclooxygenase-2 (COX-2), arachidonic acid | |
| cyclooxygenase-2 (COX-2) | Homo sapiens | arachidonic acidβOG detergent | 40.8 | 0.0137 | 2.98 × 10³ calc. | Open record: cyclooxygenase-2 (COX-2), arachidonic acid | |
| cyclooxygenase-2 (COX-2) | Homo sapiens | arachidonic acidC10E6 detergent; His6 N580A huCOX-2 | 49.9 | 0.0107 | 4.66 × 10³ calc. | Open record: cyclooxygenase-2 (COX-2), arachidonic acid | |
| cyclooxygenase-2 (COX-2) | Homo sapiens | arachidonic acidTween-20 detergent; His6 N580A huCOX-2 | 49.3 | 0.01 | 4.9 × 10³ calc. | Open record: cyclooxygenase-2 (COX-2), arachidonic acid | |
| cyclooxygenase-2 (COX-2) | Homo sapiens | arachidonic acidCHAPS detergent; His6 N580A huCOX-2 | 48.5 | 0.0156 | 3.11 × 10³ calc. | Open record: cyclooxygenase-2 (COX-2), arachidonic acid | |
| cyclooxygenase-2 (COX-2)variant S530T | Mus musculus | arachidonic acid | — | 0.0065 | — | Open record: cyclooxygenase-2 (COX-2) variant S530T, arachidonic acid |