CatLogenzyme kinetics catalog

Values CatLog read from this paper

Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties

PMID 10455188doi:10.1074/jbc.274.35.25085Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 18 records (18 values) from this paper: hyaluronan synthase 1 (HAS1), hyaluronan synthase 2 (HAS2), hyaluronan synthase 3 (HAS3) from Mus musculus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.4.1.212

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
hyaluronan synthase 1 (HAS1)Mus musculusUDP-alpha-D-glucuronic acidfixed UDP-GlcNAc at 0.1 mM; cosubstrate UDP-GlcNAc (0.1 mM)—0.0732—pH 7.1, 37 °COpen
hyaluronan synthase 1 (HAS1)Mus musculusUDP-alpha-D-glucuronic acidfixed UDP-GlcNAc at 0.5 mM; cosubstrate UDP-GlcNAc (0.5 mM)—0.0533—pH 7.1, 37 °COpen
hyaluronan synthase 1 (HAS1)Mus musculusUDP-alpha-D-glucuronic acidfixed UDP-GlcNAc at 2.0 mM; cosubstrate UDP-GlcNAc (2.0 mM)—0.0729—pH 7.1, 37 °COpen
hyaluronan synthase 1 (HAS1)Mus musculusUDP-N-acetyl-alpha-D-glucosaminefixed UDP-GlcUA at 0.05 mM; cosubstrate UDP-GlcUA (0.05 mM)—0.799—pH 7.1, 37 °COpen
hyaluronan synthase 1 (HAS1)Mus musculusUDP-N-acetyl-alpha-D-glucosaminefixed UDP-GlcUA at 0.2 mM; cosubstrate UDP-GlcUA (0.2 mM)—0.5009—pH 7.1, 37 °COpen
hyaluronan synthase 1 (HAS1)Mus musculusUDP-N-acetyl-alpha-D-glucosaminefixed UDP-GlcUA at 1.0 mM; cosubstrate UDP-GlcUA (1.0 mM)—1.011—pH 7.1, 37 °COpen
hyaluronan synthase 2 (HAS2)Mus musculusUDP-alpha-D-glucuronic acidfixed UDP-GlcNAc at 0.1 mM; cosubstrate UDP-GlcNAc (0.1 mM)—0.0329—pH 7.1, 37 °COpen
hyaluronan synthase 2 (HAS2)Mus musculusUDP-alpha-D-glucuronic acidfixed UDP-GlcNAc at 0.5 mM; cosubstrate UDP-GlcNAc (0.5 mM)—0.0292—pH 7.1, 37 °COpen
hyaluronan synthase 2 (HAS2)Mus musculusUDP-alpha-D-glucuronic acidfixed UDP-GlcNAc at 2.0 mM; cosubstrate UDP-GlcNAc (2.0 mM)—0.03—pH 7.1, 37 °COpen
hyaluronan synthase 2 (HAS2)Mus musculusUDP-N-acetyl-alpha-D-glucosaminefixed UDP-GlcUA at 0.05 mM; cosubstrate UDP-GlcUA (0.05 mM)—0.1076—pH 7.1, 37 °COpen
hyaluronan synthase 2 (HAS2)Mus musculusUDP-N-acetyl-alpha-D-glucosaminefixed UDP-GlcUA at 0.2 mM; cosubstrate UDP-GlcUA (0.2 mM)—0.3306—pH 7.1, 37 °COpen
hyaluronan synthase 2 (HAS2)Mus musculusUDP-N-acetyl-alpha-D-glucosaminefixed UDP-GlcUA at 1.0 mM; cosubstrate UDP-GlcUA (1.0 mM)—0.3482—pH 7.1, 37 °COpen
hyaluronan synthase 3 (HAS3)Mus musculusUDP-alpha-D-glucuronic acidfixed UDP-GlcNAc at 0.1 mM; cosubstrate UDP-GlcNAc (0.1 mM)—0.0342—pH 7.1, 37 °COpen
hyaluronan synthase 3 (HAS3)Mus musculusUDP-alpha-D-glucuronic acidfixed UDP-GlcNAc at 0.5 mM; cosubstrate UDP-GlcNAc (0.5 mM)—0.0351—pH 7.1, 37 °COpen
hyaluronan synthase 3 (HAS3)Mus musculusUDP-alpha-D-glucuronic acidfixed UDP-GlcNAc at 2.0 mM; cosubstrate UDP-GlcNAc (2.0 mM)—0.0346—pH 7.1, 37 °COpen
hyaluronan synthase 3 (HAS3)Mus musculusUDP-N-acetyl-alpha-D-glucosaminefixed UDP-GlcUA at 0.05 mM; cosubstrate UDP-GlcUA (0.05 mM)—0.0821—pH 7.1, 37 °COpen
hyaluronan synthase 3 (HAS3)Mus musculusUDP-N-acetyl-alpha-D-glucosaminefixed UDP-GlcUA at 0.2 mM; cosubstrate UDP-GlcUA (0.2 mM)—0.2233—pH 7.1, 37 °COpen
hyaluronan synthase 3 (HAS3)Mus musculusUDP-N-acetyl-alpha-D-glucosaminefixed UDP-GlcUA at 1.0 mM; cosubstrate UDP-GlcUA (1.0 mM)—0.2472—pH 7.1, 37 °COpen