Values CatLog read from this paper
A Comparative Study for the Incorporation of 8-oxo-dATP in DNA by Human DNA Polymerases
PMID 41898401doi:10.3390/ijms27062537Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (36 values) from this paper: DNA polymerase β (Pol β), DNA polymerase ε catalytic subunit (Pol ε, p261) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| DNA polymerase β (Pol β) | Homo sapiens | 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphateincorporation opposite template T at the +1 position | 0.0055 | 0.0545 | 0.105 | pH 7.4, 37 °C | Open record: DNA polymerase β (Pol β), 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphate |
| DNA polymerase β (Pol β) | Homo sapiens | 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphateincorporation opposite template T at the +1 position | 0.0015 | 0.0221 | 0.085 | pH 7.4, 37 °C | Open record: DNA polymerase β (Pol β), 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphate |
| DNA polymerase β (Pol β) | Homo sapiens | 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphateincorporation opposite template G at the +1 position | 2 × 10⁻⁴ | 0.1442 | 0.0015 | pH 7.4, 37 °C | Open record: DNA polymerase β (Pol β), 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphate |
| DNA polymerase β (Pol β) | Homo sapiens | 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphateincorporation opposite template G at the +1 position | 1.5 × 10⁻⁵ | 0.0893 | 2.3 × 10⁻⁴ | pH 7.4, 37 °C | Open record: DNA polymerase β (Pol β), 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphate |
| DNA polymerase β (Pol β) | Homo sapiens | 2'-deoxyadenosine 5'-triphosphateincorporation opposite template T at the +1 position | 0.91 | 0.0152 | 63 | pH 7.4, 37 °C | Open record: DNA polymerase β (Pol β), 2'-deoxyadenosine 5'-triphosphate |
| DNA polymerase β (Pol β) | Homo sapiens | 2'-deoxyadenosine 5'-triphosphateincorporation opposite template T at the +1 position | 0.325 | 0.0953 | 4 | pH 7.4, 37 °C | Open record: DNA polymerase β (Pol β), 2'-deoxyadenosine 5'-triphosphate |
| DNA polymerase β (Pol β) | Homo sapiens | 2'-deoxyadenosine 5'-triphosphateincorporation opposite template G at the +1 position | 2.2 × 10⁻⁴ | 0.1816 | 0.0013 | pH 7.4, 37 °C | Open record: DNA polymerase β (Pol β), 2'-deoxyadenosine 5'-triphosphate |
| DNA polymerase β (Pol β) | Homo sapiens | 2'-deoxyadenosine 5'-triphosphateincorporation opposite template G at the +1 position | 4 × 10⁻⁵ | 0.1403 | 4.3 × 10⁻⁴ | pH 7.4, 37 °C | Open record: DNA polymerase β (Pol β), 2'-deoxyadenosine 5'-triphosphate |
| DNA polymerase ε catalytic subunit (Pol ε, p261)variant D275N/E277Q (exo-) | Homo sapiens | 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphateincorporation opposite template T at the +1 position | 0.0027 | 0.0144 | 0.22 | pH 7.4, 37 °C | Open record: DNA polymerase ε catalytic subunit (Pol ε, p261) variant D275N/E277Q (exo-), 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphate |
| DNA polymerase ε catalytic subunit (Pol ε, p261)variant D275N/E277Q (exo-) | Homo sapiens | 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphateincorporation opposite template G at the +1 position | 0.0025 | 0.0963 | 0.033 | pH 7.4, 37 °C | Open record: DNA polymerase ε catalytic subunit (Pol ε, p261) variant D275N/E277Q (exo-), 2'-deoxy-7,8-dihydro-8-oxoadenosine-5'-triphosphate |
| DNA polymerase ε catalytic subunit (Pol ε, p261)variant D275N/E277Q (exo-) | Homo sapiens | 2'-deoxyadenosine 5'-triphosphateincorporation opposite template T at the +1 position | 0.018 | 0.0019 | 10.2 | pH 7.4, 37 °C | Open record: DNA polymerase ε catalytic subunit (Pol ε, p261) variant D275N/E277Q (exo-), 2'-deoxyadenosine 5'-triphosphate |
| DNA polymerase ε catalytic subunit (Pol ε, p261)variant D275N/E277Q (exo-) | Homo sapiens | 2'-deoxyadenosine 5'-triphosphateincorporation opposite template G at the +1 position | 0.0028 | 0.1083 | 0.027 | pH 7.4, 37 °C | Open record: DNA polymerase ε catalytic subunit (Pol ε, p261) variant D275N/E277Q (exo-), 2'-deoxyadenosine 5'-triphosphate |