Values CatLog read from this paper
Human and Plasmodium serine hydroxymethyltransferases differ in rate-limiting steps and pH-dependent substrate inhibition behavior
PMID 28760597doi:10.1016/j.abb.2017.07.017Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 21 records (51 values) from this paper: human cytosolic serine hydroxymethyltransferase (hcSHMT), Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) from Homo sapiens, Plasmodium vivax.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | (6S)-tetrahydrofolate | — | 0.005 | 6 × 10³ | pH 6.6, 25 °C | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), (6S)-tetrahydrofolate |
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | (6S)-tetrahydrofolate | — | 0.011 | 1909 | pH 7.1, 25 °C | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), (6S)-tetrahydrofolate |
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | (6S)-tetrahydrofolate | — | 0.018 | 1.1 × 10³ | pH 7.5, 25 °C | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), (6S)-tetrahydrofolate |
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | (6S)-tetrahydrofolate | — | 0.049 | 404 | pH 7.9, 25 °C | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), (6S)-tetrahydrofolate |
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | (6S)-tetrahydrofolate | — | 0.094 | 209 | pH 8.3, 25 °C | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), (6S)-tetrahydrofolate |
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | L-serine | 30 | 0.42 | 71 | pH 6.6, 25 °C | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), L-serine |
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | L-serine | 21 | 0.28 | 75 | pH 7.1, 25 °C | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), L-serine |
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | L-serine | 19.8 | 0.22 | 90 | pH 7.5, 25 °C | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), L-serine |
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | L-serine | 19.8 | 0.18 | 110 | pH 7.9, 25 °C | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), L-serine |
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | L-serine | 19.6 | 0.16 | 123 | pH 8.3, 25 °C | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), L-serine |
| human cytosolic serine hydroxymethyltransferase (hcSHMT) | Homo sapiens | L-serine | 4.4 | — | — | pH 7 | Open record: human cytosolic serine hydroxymethyltransferase (hcSHMT), L-serine |
| Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) | Plasmodium vivax | (6S)-tetrahydrofolate | — | 0.051 | 22 | pH 6.6, 25 °C | Open record: Plasmodium vivax serine hydroxymethyltransferase (PvSHMT), (6S)-tetrahydrofolate |
| Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) | Plasmodium vivax | (6S)-tetrahydrofolate | — | 0.048 | 29 | pH 7, 25 °C | Open record: Plasmodium vivax serine hydroxymethyltransferase (PvSHMT), (6S)-tetrahydrofolate |
| Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) | Plasmodium vivax | (6S)-tetrahydrofolate | — | 0.054 | 15 | pH 7.3, 25 °C | Open record: Plasmodium vivax serine hydroxymethyltransferase (PvSHMT), (6S)-tetrahydrofolate |
| Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) | Plasmodium vivax | (6S)-tetrahydrofolate | — | 0.042 | 14 | pH 7.6, 25 °C | Open record: Plasmodium vivax serine hydroxymethyltransferase (PvSHMT), (6S)-tetrahydrofolate |
| Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) | Plasmodium vivax | (6S)-tetrahydrofolate | — | 0.038 | 11 | pH 8, 25 °C | Open record: Plasmodium vivax serine hydroxymethyltransferase (PvSHMT), (6S)-tetrahydrofolate |
| Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) | Plasmodium vivax | L-serine | 1.1 | 0.3 | 3.7 | pH 6.6, 25 °C | Open record: Plasmodium vivax serine hydroxymethyltransferase (PvSHMT), L-serine |
| Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) | Plasmodium vivax | L-serine | 1.41 | 0.23 | 6.1 | pH 7, 25 °C | Open record: Plasmodium vivax serine hydroxymethyltransferase (PvSHMT), L-serine |
| Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) | Plasmodium vivax | L-serine | 0.81 | 0.2 | 4.1 | pH 7.3, 25 °C | Open record: Plasmodium vivax serine hydroxymethyltransferase (PvSHMT), L-serine |
| Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) | Plasmodium vivax | L-serine | 0.57 | 0.11 | 5.2 | pH 7.6, 25 °C | Open record: Plasmodium vivax serine hydroxymethyltransferase (PvSHMT), L-serine |
| Plasmodium vivax serine hydroxymethyltransferase (PvSHMT) | Plasmodium vivax | L-serine | 0.41 | 0.12 | 3.4 | pH 8, 25 °C | Open record: Plasmodium vivax serine hydroxymethyltransferase (PvSHMT), L-serine |