CatLogenzyme kinetics catalog

Values CatLog read from this paper

Arg-85 and Thr-430 in murine 5-aminolevulinate synthase coordinate acyl-CoA-binding and contribute to substrate specificity

PMID 19562746doi:10.1002/pro.195Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 38 records (95 values) from this paper: 5-aminolevulinate synthase (murine erythroid ALAS, eALAS) from Mus musculus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.3.1.37

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)Mus musculusbutyryl-coenzyme A0.1050.00611730 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)Mus musculusglutaryl-coenzyme A0.1170.0176.830 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)Mus musculusglycinecosubstrate succinyl-CoA—24.20.007230 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)Mus musculusglycinecosubstrate octanoyl-CoA—17.10.002330 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)Mus musculusglycinecosubstrate butyryl-CoA—29.30.004330 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)Mus musculusglycinecosubstrate β-hydroxybutyryl-CoA—22.10.002830 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)Mus musculusglycinecosubstrate glutaryl-CoA—28.40.004830 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)Mus musculusoctanoyl-coenzyme A0.0575.1 × 10⁻⁴11330 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)Mus musculussuccinyl-coenzyme A0.1670.00296030 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)Mus musculusβ-hydroxybutyryl-coenzyme A0.0670.00986.830 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85KMus musculusbutyryl-coenzyme A0.170.00276230 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85KMus musculusglutaryl-coenzyme A0.0050.00750.6730 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85KMus musculusglycinecosubstrate succinyl-CoA—200.005330 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85KMus musculusglycinecosubstrate octanoyl-CoA—25.20.008730 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85KMus musculusglycinecosubstrate butyryl-CoA—17.20.008330 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85KMus musculusglycinecosubstrate β-hydroxybutyryl-CoA—18.20.002330 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85KMus musculusglycinecosubstrate glutaryl-CoA—21.21.7 × 10⁻⁴30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85KMus musculusoctanoyl-coenzyme A0.1720.001511730 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85KMus musculussuccinyl-coenzyme A0.1070.01248.830 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85KMus musculusβ-hydroxybutyryl-coenzyme A0.0470.00558.530 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85LMus musculusbutyryl-coenzyme A0.03350.00933.530 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85LMus musculusglutaryl-coenzyme A0.0370.03011.230 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85LMus musculusglycinecosubstrate succinyl-CoA—63.11.7 × 10⁻⁴30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85LMus musculusglycinecosubstrate octanoyl-CoA—55.25 × 10⁻⁴30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85LMus musculusglycinecosubstrate butyryl-CoA—70.35 × 10⁻⁴30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85LMus musculusglycinecosubstrate β-hydroxybutyryl-CoA—59.11.8 × 10⁻⁴30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85LMus musculusglycinecosubstrate glutaryl-CoA—70.61.33 × 10⁻⁵30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85LMus musculusoctanoyl-coenzyme A0.035.5 × 10⁻⁴5530 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85LMus musculussuccinyl-coenzyme A0.01570.02030.8330 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85LMus musculusβ-hydroxybutyryl-coenzyme A0.01080.00611.830 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85L/T430VMus musculusbutyryl-coenzyme A0.0015.4 × 10⁻⁴0.530 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85L/T430VMus musculusglycinecosubstrate succinyl-CoA—98.41.7 × 10⁻⁵30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85L/T430VMus musculusglycinecosubstrate octanoyl-CoA—74.21.7 × 10⁻⁷30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85L/T430VMus musculusglycinecosubstrate butyryl-CoA—88.21.02 × 10⁻⁵30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85L/T430VMus musculusglycinecosubstrate β-hydroxybutyryl-CoA—92.21.7 × 10⁻⁸30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85L/T430VMus musculusoctanoyl-coenzyme A1.7 × 10⁻⁵0.01729.3 × 10⁻⁴30 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85L/T430VMus musculussuccinyl-coenzyme A0.00180.00960.1730 °COpen
5-aminolevulinate synthase (murine erythroid ALAS, eALAS)variant R85L/T430VMus musculusβ-hydroxybutyryl-coenzyme A1.7 × 10⁻⁶0.07422.2 × 10⁻⁵30 °COpen