CatLogenzyme kinetics catalog

Values CatLog read from this paper

TEM-109 (CMT-5), a natural complex mutant of TEM-1 beta-lactamase combining the amino acid substitutions of TEM-6 and TEM-33 (IRT-5)

PMID 16251281doi:10.1128/aac.49.11.4443-4447.2005Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 28 records (84 values) from this paper: β-lactamase TEM-109 (CMT-5), β-lactamase TEM-6, β-lactamase TEM-1 and 1 more from Escherichia coli.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.5.2.6

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
β-lactamase TEM-1Escherichia coliAmoxicillin11250.0157.7 × 10⁴Open
β-lactamase TEM-1Escherichia coliBenzylpenicillin1.5 × 10³0.0344.4 × 10⁴Open
β-lactamase TEM-1Escherichia coliCephalothin1650.242700Open
β-lactamase TEM-1Escherichia coliPiperacillin1.25 × 10³0.0552.3 × 10⁴Open
β-lactamase TEM-1Escherichia coliTicarcillin1350.0364 × 10³Open
β-lactamase TEM-109 (CMT-5)variant TEM-109 (M69L/E104K/R164H)Escherichia coliAmoxicillin660.0154 × 10³Open
β-lactamase TEM-109 (CMT-5)variant TEM-109 (M69L/E104K/R164H)Escherichia coliAztreonam380.13300Open
β-lactamase TEM-109 (CMT-5)variant TEM-109 (M69L/E104K/R164H)Escherichia coliBenzylpenicillin1710.028 × 10³Open
β-lactamase TEM-109 (CMT-5)variant TEM-109 (M69L/E104K/R164H)Escherichia coliCefotaxime210.33100Open
β-lactamase TEM-109 (CMT-5)variant TEM-109 (M69L/E104K/R164H)Escherichia coliCeftazidime560.226200Open
β-lactamase TEM-109 (CMT-5)variant TEM-109 (M69L/E104K/R164H)Escherichia coliCefuroxime220.093200Open
β-lactamase TEM-109 (CMT-5)variant TEM-109 (M69L/E104K/R164H)Escherichia coliCephalothin150.181100Open
β-lactamase TEM-109 (CMT-5)variant TEM-109 (M69L/E104K/R164H)Escherichia coliPiperacillin1520.0642 × 10³Open
β-lactamase TEM-109 (CMT-5)variant TEM-109 (M69L/E104K/R164H)Escherichia coliTicarcillin420.0143 × 10³Open
β-lactamase TEM-33 (IRT-5)variant TEM-33 (M69L)Escherichia coliAmoxicillin1110.0235 × 10³Open
β-lactamase TEM-33 (IRT-5)variant TEM-33 (M69L)Escherichia coliBenzylpenicillin1500.0151 × 10⁴Open
β-lactamase TEM-33 (IRT-5)variant TEM-33 (M69L)Escherichia coliCephalothin50.31710Open
β-lactamase TEM-33 (IRT-5)variant TEM-33 (M69L)Escherichia coliPiperacillin830.0156 × 10³Open
β-lactamase TEM-33 (IRT-5)variant TEM-33 (M69L)Escherichia coliTicarcillin20.007200Open
β-lactamase TEM-6variant TEM-6 (E104K/R164H)Escherichia coliAmoxicillin310.0084 × 10³Open
β-lactamase TEM-6variant TEM-6 (E104K/R164H)Escherichia coliAztreonam220.051400Open
β-lactamase TEM-6variant TEM-6 (E104K/R164H)Escherichia coliBenzylpenicillin1340.011.3 × 10⁴Open
β-lactamase TEM-6variant TEM-6 (E104K/R164H)Escherichia coliCefotaxime90.071100Open
β-lactamase TEM-6variant TEM-6 (E104K/R164H)Escherichia coliCeftazidime1050.247400Open
β-lactamase TEM-6variant TEM-6 (E104K/R164H)Escherichia coliCefuroxime40.044100Open
β-lactamase TEM-6variant TEM-6 (E104K/R164H)Escherichia coliCephalothin740.247300Open
β-lactamase TEM-6variant TEM-6 (E104K/R164H)Escherichia coliPiperacillin1070.0186 × 10³Open
β-lactamase TEM-6variant TEM-6 (E104K/R164H)Escherichia coliTicarcillin230.0021.4 × 10⁴Open