Values CatLog read from this paper

The second-shell metal ligands of human arginase affect coordination of the nucleophile and substrate

PMID 21053939doi:10.1021/bi101542tOpen in Browse

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CatLog read 14 records (42 values) from this paper: human arginase I (hArgI) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.5.3.1

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
human arginase I (hArgI)variant D181EHomo sapiensL-arginine3440.271.27 × 10³pH 7.4, 37 °COpen record: human arginase I (hArgI) variant D181E, L-arginine
human arginase I (hArgI)variant D181E/S230AHomo sapiensL-arginine2200.151.47 × 10³pH 7.4, 37 °COpen record: human arginase I (hArgI) variant D181E/S230A, L-arginine
human arginase I (hArgI)variant D181NHomo sapiensL-argininewith Co(II) (100 microM CoCl2)3870.31.29 × 10³pH 7.4, 37 °COpen record: human arginase I (hArgI) variant D181N, L-arginine
human arginase I (hArgI)variant D181NHomo sapiensL-argininewith Mn(II)3603120pH 7.4, 37 °COpen record: human arginase I (hArgI) variant D181N, L-arginine
human arginase I (hArgI)variant D181N/S230GHomo sapiensL-argininewith Co(II) (100 microM CoCl2)2470.211.18 × 10³pH 7.4, 37 °COpen record: human arginase I (hArgI) variant D181N/S230G, L-arginine
human arginase I (hArgI)variant D181N/S230GHomo sapiensL-argininewith Mn(II)5172.8185pH 7.4, 37 °COpen record: human arginase I (hArgI) variant D181N/S230G, L-arginine
human arginase I (hArgI)variant D181SHomo sapiensL-arginine3880.281.39 × 10³pH 7.4, 37 °COpen record: human arginase I (hArgI) variant D181S, L-arginine
human arginase I (hArgI)variant D181S/S230GHomo sapiensL-arginine1800.19950pH 7.4, 37 °COpen record: human arginase I (hArgI) variant D181S/S230G, L-arginine
human arginase I (hArgI)variant S230CHomo sapiensL-argininewith Co(II) (100 microM CoCl2)3270.152.18 × 10³pH 7.4, 37 °COpen record: human arginase I (hArgI) variant S230C, L-arginine
human arginase I (hArgI)variant S230CHomo sapiensL-argininewith Mn(II)2852.1136pH 7.4, 37 °COpen record: human arginase I (hArgI) variant S230C, L-arginine
human arginase I (hArgI)variant S230DHomo sapiensL-arginine1400.15930pH 7.4, 37 °COpen record: human arginase I (hArgI) variant S230D, L-arginine
human arginase I (hArgI)variant S230GHomo sapiensL-argininewith Co(II) (100 microM CoCl2)2000.082.6 × 10³pH 7.4, 37 °COpen record: human arginase I (hArgI) variant S230G, L-arginine
human arginase I (hArgI)variant S230GHomo sapiensL-argininewith Mn(II)2660.8330pH 7.4, 37 °COpen record: human arginase I (hArgI) variant S230G, L-arginine
human arginase I (hArgI)variant S230THomo sapiensL-arginine3150.161.97 × 10³pH 7.4, 37 °COpen record: human arginase I (hArgI) variant S230T, L-arginine