Values CatLog read from this paper
Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade
PMID 20940292doi:10.1074/jbc.m110.125310Open in Browse
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CatLog read 11 records (33 values) from this paper: mat-KLK8 (mature kallikrein-related peptidase-8) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | benzyloxycarbonyl-glycyl-glycyl-L-arginine-7-amino-4-methylcoumarin | 1.488 | 0.4312 | 3.452 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), benzyloxycarbonyl-glycyl-glycyl-L-arginine-7-amino-4-methylcoumarin |
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | L-prolyl-L-phenylalanyl-L-arginine-7-amino-4-methylcoumarin (free N terminus) | 4.448 | 0.1533 | 29.02 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), L-prolyl-L-phenylalanyl-L-arginine-7-amino-4-methylcoumarin (free N terminus) |
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | N-t-butoxycarbonyl-L-glutaminyl-glycyl-L-arginine-7-amino-4-methylcoumarin | 1.429 | 0.3699 | 3.864 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), N-t-butoxycarbonyl-L-glutaminyl-glycyl-L-arginine-7-amino-4-methylcoumarin |
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | N-t-butoxycarbonyl-L-glutaminyl-L-alanyl-L-arginine-7-amino-4-methylcoumarin | 5.754 | 0.1844 | 31.20 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), N-t-butoxycarbonyl-L-glutaminyl-L-alanyl-L-arginine-7-amino-4-methylcoumarin |
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | N-t-butoxycarbonyl-L-glutaminyl-L-arginyl-L-arginine-7-amino-4-methylcoumarin | 3.392 | 0.2247 | 15.10 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), N-t-butoxycarbonyl-L-glutaminyl-L-arginyl-L-arginine-7-amino-4-methylcoumarin |
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | N-t-butoxycarbonyl-L-leucyl-L-arginyl-L-arginine-7-amino-4-methylcoumarin | 1.620 | 0.1165 | 13.91 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), N-t-butoxycarbonyl-L-leucyl-L-arginyl-L-arginine-7-amino-4-methylcoumarin |
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | N-t-butoxycarbonyl-L-leucyl-L-lysyl-L-arginine-7-amino-4-methylcoumarin | 1.565 | 0.1407 | 11.12 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), N-t-butoxycarbonyl-L-leucyl-L-lysyl-L-arginine-7-amino-4-methylcoumarin |
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | N-t-butoxycarbonyl-L-phenylalanyl-L-seryl-L-arginine-7-amino-4-methylcoumarin | 3.566 | 0.2983 | 11.96 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), N-t-butoxycarbonyl-L-phenylalanyl-L-seryl-L-arginine-7-amino-4-methylcoumarin |
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | N-t-butoxycarbonyl-L-valyl-L-leucyl-L-lysine-7-amino-4-methylcoumarin | 3.637 | 0.3326 | 10.94 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), N-t-butoxycarbonyl-L-valyl-L-leucyl-L-lysine-7-amino-4-methylcoumarin |
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | N-t-butoxycarbonyl-L-valyl-L-prolyl-L-arginine-7-amino-4-methylcoumarin | 6.756 | 0.0238 | 283.4 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), N-t-butoxycarbonyl-L-valyl-L-prolyl-L-arginine-7-amino-4-methylcoumarin |
| mat-KLK8 (mature kallikrein-related peptidase-8) | Homo sapiens | N-tosyl-glycyl-L-prolyl-L-arginine-7-amino-4-methylcoumarin | 2.106 | 0.6897 | 3.054 | pH 8.5, 37 °C | Open record: mat-KLK8 (mature kallikrein-related peptidase-8), N-tosyl-glycyl-L-prolyl-L-arginine-7-amino-4-methylcoumarin |