Values CatLog read from this paper
Probing active site chemistry in SHV beta-lactamase variants at Ambler position 244. Understanding unique properties of inhibitor resistance
PMID 16803899doi:10.1074/jbc.m603222200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 15 records (35 values) from this paper: SHV-1 β-lactamase from Klebsiella pneumoniae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| SHV-1 β-lactamase | Klebsiella pneumoniae | ampicillin | 3.7 × 10³ | 0.165 | 2.2 × 10⁴ | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase, ampicillin |
| SHV-1 β-lactamase | Klebsiella pneumoniae | clavulanic acid | 2.4 | — | — | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase, clavulanic acid |
| SHV-1 β-lactamase | Klebsiella pneumoniae | nitrocefin | 290 | 0.021 | 1.4 × 10⁴ | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase, nitrocefin |
| SHV-1 β-lactamasevariant R244E | Klebsiella pneumoniae | ampicillin | 115 | 3.5 | 30 | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244E, ampicillin |
| SHV-1 β-lactamasevariant R244E | Klebsiella pneumoniae | clavulanic acid | 4.4 | — | — | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244E, clavulanic acid |
| SHV-1 β-lactamasevariant R244E | Klebsiella pneumoniae | nitrocefin | 20 | 0.25 | 80 | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244E, nitrocefin |
| SHV-1 β-lactamasevariant R244L | Klebsiella pneumoniae | ampicillin | 800 | 2.24 | 400 | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244L, ampicillin |
| SHV-1 β-lactamasevariant R244L | Klebsiella pneumoniae | clavulanic acid | 61 | — | — | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244L, clavulanic acid |
| SHV-1 β-lactamasevariant R244L | Klebsiella pneumoniae | nitrocefin | 230 | 0.59 | 400 | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244L, nitrocefin |
| SHV-1 β-lactamasevariant R244Q | Klebsiella pneumoniae | ampicillin | 1.4 × 10³ | 1.19 | 1.2 × 10³ | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244Q, ampicillin |
| SHV-1 β-lactamasevariant R244Q | Klebsiella pneumoniae | clavulanic acid | 19 | — | — | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244Q, clavulanic acid |
| SHV-1 β-lactamasevariant R244Q | Klebsiella pneumoniae | nitrocefin | 270 | 0.11 | 2.4 × 10³ | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244Q, nitrocefin |
| SHV-1 β-lactamasevariant R244S | Klebsiella pneumoniae | ampicillin | 390 | 0.255 | 1.5 × 10³ | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244S, ampicillin |
| SHV-1 β-lactamasevariant R244S | Klebsiella pneumoniae | clavulanic acid | 4.5 | — | — | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244S, clavulanic acid |
| SHV-1 β-lactamasevariant R244S | Klebsiella pneumoniae | nitrocefin | 107 | 0.055 | 2 × 10³ | pH 7.4, 25 °C | Open record: SHV-1 β-lactamase variant R244S, nitrocefin |