CatLogenzyme kinetics catalog

Values CatLog read from this paper

Role of S'1 loop residues in the substrate specificities of pepsin A and chymosin

PMID 15568804doi:10.1021/bi048440gOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 64 records (191 values) from this paper: pepsin A, chymosin from Homo sapiens, Callithrix jacchus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.23.1, EC 3.4.23.3

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
chymosinCallithrix jacchusAla-Phe-Pro-Leu-Glu-Phe-Glu-Arg-Glu-Leu630.304210pH 4, 37 °COpen
chymosinCallithrix jacchusAla-Phe-Pro-Leu-Glu-Phe-Lys-Arg-Glu-Leu2190.375590pH 4, 37 °COpen
chymosinCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Glu-Arg-Gln-Leu460.111420pH 4, 37 °COpen
chymosinCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Lys-Arg-Gln-Leu410.059700pH 4, 37 °COpen
chymosinCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-LeuLeu147-Phe148 bond280.083330pH 4, 37 °COpen
chymosinCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-LeuPhe148-Arg149 bond (block printed "(F147-R148 cleavage)")1910.1051.8 × 10³pH 4, 37 °COpen
chymosinvariant D289MCallithrix jacchusAla-Phe-Pro-Leu-Glu-Phe-Glu-Arg-Glu-Leu140.065230pH 4, 37 °COpen
chymosinvariant D289MCallithrix jacchusAla-Phe-Pro-Leu-Glu-Phe-Lys-Arg-Glu-Leu1010.288350pH 4, 37 °COpen
chymosinvariant D289MCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Glu-Arg-Gln-Leu320.054600pH 4, 37 °COpen
chymosinvariant D289MCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Lys-Arg-Gln-Leu350.072520pH 4, 37 °COpen
chymosinvariant D289MCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-LeuLeu147-Phe148 bond—0.054710pH 4, 37 °COpen
chymosinvariant D289MCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-LeuPhe148-Arg149 bond (block printed "(F147-R148 cleavage)")420.0281.5 × 10³pH 4, 37 °COpen
chymosinvariant D289M/Q298LCallithrix jacchusAla-Phe-Pro-Leu-Glu-Phe-Glu-Arg-Glu-Leu120.114100pH 4, 37 °COpen
chymosinvariant D289M/Q298LCallithrix jacchusAla-Phe-Pro-Leu-Glu-Phe-Lys-Arg-Glu-Leu430.25170pH 4, 37 °COpen
chymosinvariant D289M/Q298LCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Glu-Arg-Gln-Leu220.046500pH 4, 37 °COpen
chymosinvariant D289M/Q298LCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Lys-Arg-Gln-Leu270.087310pH 4, 37 °COpen
chymosinvariant D289M/Q298LCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-LeuLeu147-Phe148 bond160.0161 × 10³pH 4, 37 °COpen
chymosinvariant D289M/Q298LCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-LeuPhe148-Arg149 bond (block printed "(F147-R148 cleavage)")170.024700pH 4, 37 °COpen
chymosinvariant Q298LCallithrix jacchusAla-Phe-Pro-Leu-Glu-Phe-Glu-Arg-Glu-Leu520.463110pH 4, 37 °COpen
chymosinvariant Q298LCallithrix jacchusAla-Phe-Pro-Leu-Glu-Phe-Lys-Arg-Glu-Leu900.229390pH 4, 37 °COpen
chymosinvariant Q298LCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Glu-Arg-Gln-Leu170.062270pH 4, 37 °COpen
chymosinvariant Q298LCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Lys-Arg-Gln-Leu300.095320pH 4, 37 °COpen
chymosinvariant Q298LCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-LeuLeu147-Phe148 bond120.029400pH 4, 37 °COpen
chymosinvariant Q298LCallithrix jacchusLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-LeuPhe148-Arg149 bond (block printed "(F147-R148 cleavage)")490.0331.5 × 10³pH 4, 37 °COpen
pepsin AHomo sapiensAla-Phe-Pro-Leu-Glu-Phe-Glu-Arg-Glu-Leu8.90.30429pH 4, 37 °COpen
pepsin AHomo sapiensAla-Phe-Pro-Leu-Glu-Phe-Lys-Arg-Glu-Leu1.40.06921pH 4, 37 °COpen
pepsin AHomo sapiensArg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH280.054150pH 4, 37 °COpen
pepsin AHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Glu-Arg-Gln-Leu5.50.06881pH 4, 37 °COpen
pepsin AHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Lys-Arg-Gln-Leu4.20.12337pH 4, 37 °COpen
pepsin AHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-Leucleavage of the Leu147-Phe148 bond120.017720pH 4, 37 °COpen
pepsin AHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-Leucleavage of the Phe148-Arg149 bond4.40.015290pH 4, 37 °COpen
pepsin AHomo sapiensLys-Tyr-Ser-Ser-Trp-Tyr-Val-Ala-Leu150.07220pH 4, 37 °COpen
pepsin Avariant L291SHomo sapiensAla-Phe-Pro-Leu-Glu-Phe-Glu-Arg-Glu-Leu230.3666pH 4, 37 °COpen
pepsin Avariant L291SHomo sapiensAla-Phe-Pro-Leu-Glu-Phe-Lys-Arg-Glu-Leu200.24681pH 4, 37 °COpen
pepsin Avariant L291SHomo sapiensArg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH26.40.07387pH 4, 37 °COpen
pepsin Avariant L291SHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Glu-Arg-Gln-Leu6.10.06298pH 4, 37 °COpen
pepsin Avariant L291SHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Lys-Arg-Gln-Leu7.60.0985pH 4, 37 °COpen
pepsin Avariant L291SHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-Leucleavage of the Leu147-Phe148 bond150.042354pH 4, 37 °COpen
pepsin Avariant L291SHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-Leucleavage of the Phe148-Arg149 bond200.026770pH 4, 37 °COpen
pepsin Avariant L291SHomo sapiensLys-Tyr-Ser-Ser-Trp-Tyr-Val-Ala-Leu170.105160pH 4, 37 °COpen
pepsin Avariant L291S/L298QHomo sapiensAla-Phe-Pro-Leu-Glu-Phe-Glu-Arg-Glu-Leu300.46365pH 4, 37 °COpen
pepsin Avariant L291S/L298QHomo sapiensAla-Phe-Pro-Leu-Glu-Phe-Lys-Arg-Glu-Leu210.188110pH 4, 37 °COpen
pepsin Avariant L291S/L298QHomo sapiensArg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH26.50.23827pH 4, 37 °COpen
pepsin Avariant L291S/L298QHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Glu-Arg-Gln-Leu7.70.064130pH 4, 37 °COpen
pepsin Avariant L291S/L298QHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Lys-Arg-Gln-Leu110.082130pH 4, 37 °COpen
pepsin Avariant L291S/L298QHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-Leucleavage of the Leu147-Phe148 bond130.095140pH 4, 37 °COpen
pepsin Avariant L291S/L298QHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-Leucleavage of the Phe148-Arg149 bond320.038840pH 4, 37 °COpen
pepsin Avariant L291S/L298QHomo sapiensLys-Tyr-Ser-Ser-Trp-Tyr-Val-Ala-Leu210.184120pH 4, 37 °COpen
pepsin Avariant L298QHomo sapiensAla-Phe-Pro-Leu-Glu-Phe-Glu-Arg-Glu-Leu260.41163pH 4, 37 °COpen
pepsin Avariant L298QHomo sapiensAla-Phe-Pro-Leu-Glu-Phe-Lys-Arg-Glu-Leu120.13986pH 4, 37 °COpen
pepsin Avariant L298QHomo sapiensArg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2300.35785pH 4, 37 °COpen
pepsin Avariant L298QHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Glu-Arg-Gln-Leu9.40.085110pH 4, 37 °COpen
pepsin Avariant L298QHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Lys-Arg-Gln-Leu100.11689pH 4, 37 °COpen
pepsin Avariant L298QHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-Leucleavage of the Leu147-Phe148 bond160.053290pH 4, 37 °COpen
pepsin Avariant L298QHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-Leucleavage of the Phe148-Arg149 bond340.0281.2 × 10³pH 4, 37 °COpen
pepsin Avariant L298QHomo sapiensLys-Tyr-Ser-Ser-Trp-Tyr-Val-Ala-Leu610.324190pH 4, 37 °COpen
pepsin Avariant M289DHomo sapiensAla-Phe-Pro-Leu-Glu-Phe-Glu-Arg-Glu-Leu7.90.0986pH 4, 37 °COpen
pepsin Avariant M289DHomo sapiensAla-Phe-Pro-Leu-Glu-Phe-Lys-Arg-Glu-Leu130.23358pH 4, 37 °COpen
pepsin Avariant M289DHomo sapiensArg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2230.139170pH 4, 37 °COpen
pepsin Avariant M289DHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Glu-Arg-Gln-Leu4.90.08461pH 4, 37 °COpen
pepsin Avariant M289DHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Lys-Arg-Gln-Leu3.10.08238pH 4, 37 °COpen
pepsin Avariant M289DHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-Leucleavage of the Leu147-Phe148 bond120.022540pH 4, 37 °COpen
pepsin Avariant M289DHomo sapiensLys-Ile-Pro-Tyr-Ile-Leu-Phe-Arg-Gln-Leucleavage of the Phe148-Arg149 bond120.014850pH 4, 37 °COpen
pepsin Avariant M289DHomo sapiensLys-Tyr-Ser-Ser-Trp-Tyr-Val-Ala-Leu230.104220pH 4, 37 °COpen