Values CatLog read from this paper
CMT-type beta-lactamase TEM-125, an emerging problem for extended-spectrum beta-lactamase detection
PMID 16801418doi:10.1128/aac.01639-05Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 23 records (67 values) from this paper: β-lactamase TEM-12, β-lactamase TEM-125, β-lactamase TEM-39 from Escherichia coli.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 2 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| β-lactamase TEM-12variant TEM-12 (R164S) | Escherichia coli | amoxicillin | 60 | 0.0075 | 8 × 10³ | Open record: β-lactamase TEM-12 variant TEM-12 (R164S), amoxicillin | |
| β-lactamase TEM-12variant TEM-12 (R164S) | Escherichia coli | aztreonam | 2 | 0.247 | 8 | Open record: β-lactamase TEM-12 variant TEM-12 (R164S), aztreonam | |
| β-lactamase TEM-12variant TEM-12 (R164S) | Escherichia coli | benzylpenicillin | 80 | 0.007 | 1.1 × 10⁴ | Open record: β-lactamase TEM-12 variant TEM-12 (R164S), benzylpenicillin | |
| β-lactamase TEM-12variant TEM-12 (R164S) | Escherichia coli | cefotaxime | 10.6 | 0.32 | 30 | Open record: β-lactamase TEM-12 variant TEM-12 (R164S), cefotaxime | |
| β-lactamase TEM-12variant TEM-12 (R164S) | Escherichia coli | ceftazidime | 11.1 | 0.254 | 40 | Open record: β-lactamase TEM-12 variant TEM-12 (R164S), ceftazidime | |
| β-lactamase TEM-12variant TEM-12 (R164S) | Escherichia coli | cefuroxime | 1.6 | 0.081 | 20 calc. | Open record: β-lactamase TEM-12 variant TEM-12 (R164S), cefuroxime | |
| β-lactamase TEM-12variant TEM-12 (R164S) | Escherichia coli | cephalothin | 46 | 0.327 | 140 calc. | Open record: β-lactamase TEM-12 variant TEM-12 (R164S), cephalothin | |
| β-lactamase TEM-12variant TEM-12 (R164S) | Escherichia coli | piperacillin | 89 | 0.015 | 6 × 10³ | Open record: β-lactamase TEM-12 variant TEM-12 (R164S), piperacillin | |
| β-lactamase TEM-12variant TEM-12 (R164S) | Escherichia coli | ticarcillin | 19 | 0.012 | 1.6 × 10³ | Open record: β-lactamase TEM-12 variant TEM-12 (R164S), ticarcillin | |
| β-lactamase TEM-125variant TEM-125 (F16L/M69L/R164S/W165R/N276D) | Escherichia coli | amoxicillin | 68 | 0.0212 | 3.2 × 10³ | Open record: β-lactamase TEM-125 variant TEM-125 (F16L/M69L/R164S/W165R/N276D), amoxicillin | |
| β-lactamase TEM-125variant TEM-125 (F16L/M69L/R164S/W165R/N276D) | Escherichia coli | aztreonam | 0.7 | 0.45 | 1.5 | Open record: β-lactamase TEM-125 variant TEM-125 (F16L/M69L/R164S/W165R/N276D), aztreonam | |
| β-lactamase TEM-125variant TEM-125 (F16L/M69L/R164S/W165R/N276D) | Escherichia coli | benzylpenicillin | 136.5 | 0.03 | 4.6 × 10³ | Open record: β-lactamase TEM-125 variant TEM-125 (F16L/M69L/R164S/W165R/N276D), benzylpenicillin | |
| β-lactamase TEM-125variant TEM-125 (F16L/M69L/R164S/W165R/N276D) | Escherichia coli | cefotaxime | 0.8 | 0.254 | 3 | Open record: β-lactamase TEM-125 variant TEM-125 (F16L/M69L/R164S/W165R/N276D), cefotaxime | |
| β-lactamase TEM-125variant TEM-125 (F16L/M69L/R164S/W165R/N276D) | Escherichia coli | ceftazidime | 3.7 | 0.318 | 12 | Open record: β-lactamase TEM-125 variant TEM-125 (F16L/M69L/R164S/W165R/N276D), ceftazidime | |
| β-lactamase TEM-125variant TEM-125 (F16L/M69L/R164S/W165R/N276D) | Escherichia coli | cefuroxime | 0.6 | 0.18 | 3 | Open record: β-lactamase TEM-125 variant TEM-125 (F16L/M69L/R164S/W165R/N276D), cefuroxime | |
| β-lactamase TEM-125variant TEM-125 (F16L/M69L/R164S/W165R/N276D) | Escherichia coli | cephalothin | 4.6 | 0.387 | 12 | Open record: β-lactamase TEM-125 variant TEM-125 (F16L/M69L/R164S/W165R/N276D), cephalothin | |
| β-lactamase TEM-125variant TEM-125 (F16L/M69L/R164S/W165R/N276D) | Escherichia coli | piperacillin | 314 | 0.089 | 3.5 × 10³ | Open record: β-lactamase TEM-125 variant TEM-125 (F16L/M69L/R164S/W165R/N276D), piperacillin | |
| β-lactamase TEM-125variant TEM-125 (F16L/M69L/R164S/W165R/N276D) | Escherichia coli | ticarcillin | 9.6 | 0.065 | 100 | Open record: β-lactamase TEM-125 variant TEM-125 (F16L/M69L/R164S/W165R/N276D), ticarcillin | |
| β-lactamase TEM-39variant TEM-39 (M69L/W165R/N276D) | Escherichia coli | amoxicillin | 2.5 × 10³ | 0.334 | 7.5 × 10³ | Open record: β-lactamase TEM-39 variant TEM-39 (M69L/W165R/N276D), amoxicillin | |
| β-lactamase TEM-39variant TEM-39 (M69L/W165R/N276D) | Escherichia coli | benzylpenicillin | 3.57 × 10³ | 0.233 | 1.53 × 10⁴ | Open record: β-lactamase TEM-39 variant TEM-39 (M69L/W165R/N276D), benzylpenicillin | |
| β-lactamase TEM-39variant TEM-39 (M69L/W165R/N276D) | Escherichia coli | cephalothin | 7.1 | 0.311 | 20 | Open record: β-lactamase TEM-39 variant TEM-39 (M69L/W165R/N276D), cephalothin | |
| β-lactamase TEM-39variant TEM-39 (M69L/W165R/N276D) | Escherichia coli | piperacillin | 3.32 × 10³ | 0.253 | 1.31 × 10⁴ | Open record: β-lactamase TEM-39 variant TEM-39 (M69L/W165R/N276D), piperacillin | |
| β-lactamase TEM-39variant TEM-39 (M69L/W165R/N276D) | Escherichia coli | ticarcillin | 260 | 0.443 | 600 | Open record: β-lactamase TEM-39 variant TEM-39 (M69L/W165R/N276D), ticarcillin |