Values CatLog read from this paper
Relationship of Catalysis and Active Site Loop Dynamics in the (βα)8-Barrel Enzyme Indole-3-glycerol Phosphate Synthase
PMID 29498826doi:10.1021/acs.biochem.8b00167Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (17 values) from this paper: indole-3-glycerol phosphate synthase (ssIGPS) from Sulfolobus solfataricus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 1 kcat/Km value marked “calc.” from kcat and Km; no printed kcat/Km was read for that record.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| indole-3-glycerol phosphate synthase (ssIGPS) | Sulfolobus solfataricus | 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate | 0.11 | 8.5 × 10⁻⁵ | 1.18 × 10³ | pH 7.5, 25 °C | Open record: indole-3-glycerol phosphate synthase (ssIGPS), 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate |
| indole-3-glycerol phosphate synthase (ssIGPS) | Sulfolobus solfataricus | 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate | 2.1 | 1.05 × 10⁻⁴ | 2 × 10⁴ | pH 7.5, 60 °C | Open record: indole-3-glycerol phosphate synthase (ssIGPS), 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate |
| indole-3-glycerol phosphate synthase (ssIGPS)variant F246S | Sulfolobus solfataricus | 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate | 0.32 | 0.0013 | 240 | pH 7.5, 25 °C | Open record: indole-3-glycerol phosphate synthase (ssIGPS) variant F246S, 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate |
| indole-3-glycerol phosphate synthase (ssIGPS)variant G212E | Sulfolobus solfataricus | 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate | 0.16 | 0.0217 | 7.4 calc. | pH 7.5, 25 °C | Open record: indole-3-glycerol phosphate synthase (ssIGPS) variant G212E, 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate |
| indole-3-glycerol phosphate synthase (ssIGPS)variant L236Q | Sulfolobus solfataricus | 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate | 0.2 | 0.0034 | 60 | pH 7.5, 25 °C | Open record: indole-3-glycerol phosphate synthase (ssIGPS) variant L236Q, 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate |
| indole-3-glycerol phosphate synthase (ssIGPS)variant M237T | Sulfolobus solfataricus | 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate | 0.23 | 0.0029 | 80 | pH 7.5, 25 °C | Open record: indole-3-glycerol phosphate synthase (ssIGPS) variant M237T, 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate |