Values CatLog read from this paper
Analysis of the kinetics of prothrombin activation and evidence that two equilibrating forms of prothrombinase are involved in the process
PMID 12496269doi:10.1074/jbc.m206413200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 13 records (36 values) from this paper: factor Xa from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 3 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| factor Xa | Homo sapiens | fragment 1.2:prethrombin-2with factor Va (prothrombinase): 0.02 nM factor Xa | 114 | 5.77 × 10⁻⁴ | 1.98 × 10⁵ | Open record: factor Xa, fragment 1.2:prethrombin-2 | |
| factor Xa | Homo sapiens | fragment 1.2:prethrombin-2without factor Va: 20 nM factor Xa | 0.0057 | 7.8 × 10⁻⁴ | 7.3 | Open record: factor Xa, fragment 1.2:prethrombin-2 | |
| factor Xa | Homo sapiens | meizothrombinwith factor Va (prothrombinase): 0.02 nM factor Xa | 150 | 6.53 × 10⁻⁴ | 2.3 × 10⁵ | Open record: factor Xa, meizothrombin | |
| factor Xa | Homo sapiens | meizothrombinwithout factor Va: 20 nM factor Xa | 6.39 | 9.45 × 10⁻⁴ | 6.76 × 10³ | Open record: factor Xa, meizothrombin | |
| factor Xa | Homo sapiens | R155A/R284A/R271A prothrombinwith factor Va (prothrombinase): 0.02 nM factor Xa | 110 | 3.55 × 10⁻⁴ | 3.09 × 10⁵ | Open record: factor Xa, R155A/R284A/R271A prothrombin | |
| factor Xa | Homo sapiens | R155A/R284A/R271A prothrombinwithout factor Va: 20 nM factor Xa | 0.0068 | 4.5 × 10⁻⁴ | 15 | Open record: factor Xa, R155A/R284A/R271A prothrombin | |
| factor Xa | Homo sapiens | R155A/R284A/R271A/S525C prothrombin labeled with fluorescein at Cys525 | 190 | 9.24 × 10⁻⁴ | 2.1 × 10⁵ calc. | Open record: factor Xa, R155A/R284A/R271A/S525C prothrombin labeled with fluorescein at Cys525 | |
| factor Xa | Homo sapiens | R155A/R284A/R320A prothrombinwith factor Va (prothrombinase): 0.02 nM factor Xa | 114 | 3.93 × 10⁻⁴ | 2.91 × 10⁵ | Open record: factor Xa, R155A/R284A/R320A prothrombin | |
| factor Xa | Homo sapiens | R155A/R284A/R320A prothrombinwithout factor Va: 20 nM factor Xa | 0.324 | 5.04 × 10⁻⁴ | 640 | Open record: factor Xa, R155A/R284A/R320A prothrombin | |
| factor Xa | Homo sapiens | recombinant wild-type human prothrombinwith factor Va (prothrombinase): 0.02 nM factor Xa | 108 | 4.11 × 10⁻⁴ | 2.62 × 10⁵ | Open record: factor Xa, recombinant wild-type human prothrombin | |
| factor Xa | Homo sapiens | recombinant wild-type human prothrombinwithout factor Va: 20 nM factor Xa | 0.0045 | 6.82 × 10⁻⁴ | 6.6 | Open record: factor Xa, recombinant wild-type human prothrombin | |
| factor Xa | Homo sapiens | S525C prothrombin labeled with fluorescein at Cys525competition with rP2-II | 107 | 3.86 × 10⁻⁴ | 2.77 × 10⁵ calc. | Open record: factor Xa, S525C prothrombin labeled with fluorescein at Cys525 | |
| factor Xa | Homo sapiens | S525C prothrombin labeled with fluorescein at Cys525competition with rMZ-II | 127 | 5.57 × 10⁻⁴ | 2.28 × 10⁵ calc. | Open record: factor Xa, S525C prothrombin labeled with fluorescein at Cys525 |