Values CatLog read from this paper
Functional role of residues involved in substrate binding of human 4-hydroxyphenylpyruvate dioxygenase
PMID 34047349doi:10.1042/bcj20210005Open in Browse
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CatLog read 10 records (30 values) from this paper: 4-hydroxyphenylpyruvate dioxygenase from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 4-hydroxyphenylpyruvate dioxygenase | Homo sapiens | 4-hydroxyphenylpyruvate | 2 | 0.2 | 10 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenasevariant N363A | Homo sapiens | 4-hydroxyphenylpyruvate | 0.6 | 0.3 | 2 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase variant N363A, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenasevariant N363D | Homo sapiens | 4-hydroxyphenylpyruvate | 0.3 | 0.5 | 0.6 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase variant N363D, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenasevariant N363Q | Homo sapiens | 4-hydroxyphenylpyruvate | 0.3 | 0.4 | 0.7 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase variant N363Q, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenasevariant Q265E | Homo sapiens | 4-hydroxyphenylpyruvate | 0.1 | 0.9 | 0.2 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase variant Q265E, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenasevariant Q334A | Homo sapiens | 4-hydroxyphenylpyruvate | 1 | 0.3 | 4 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase variant Q334A, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenasevariant Q334A/N363D | Homo sapiens | 4-hydroxyphenylpyruvate | 0.2 | 0.5 | 0.5 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase variant Q334A/N363D, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenasevariant Q334A/N363Q | Homo sapiens | 4-hydroxyphenylpyruvate | 0.2 | 0.6 | 0.3 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase variant Q334A/N363Q, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenasevariant Q334N | Homo sapiens | 4-hydroxyphenylpyruvate | 0.06 | 0.2 | 0.3 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase variant Q334N, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenasevariant Q334N/N363Q | Homo sapiens | 4-hydroxyphenylpyruvate | 0.09 | 0.5 | 0.2 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase variant Q334N/N363Q, 4-hydroxyphenylpyruvate |