CatLogenzyme kinetics catalog

Values CatLog read from this paper

Functional characterization and categorization of missense mutations that cause methylmalonyl-CoA mutase (MUT) deficiency

PMID 25125334doi:10.1002/humu.22633Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 18 records (18 values) from this paper: methylmalonyl-CoA mutase (MUT) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 5.4.99.2

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
methylmalonyl-CoA mutase (MUT)Homo sapiensadenosylcobalamin0.1 M potassium phosphate buffer pH 7.4; 30 min at 37 °C—4.7 × 10⁻⁶—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)Homo sapiensadenosylcobalamin0.1 M potassium phosphate buffer; 50-100 µg cell protein—4.74 × 10⁻⁶—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant F573SHomo sapiensadenosylcobalamin—2.14 × 10⁻⁵—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant G426RHomo sapiensadenosylcobalamin—0.009261—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant G648DHomo sapiensadenosylcobalamin—0.006612—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant G717VHomo sapiensadenosylcobalamin—0.008484—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant L736FHomo sapiensadenosylcobalamin—2.21 × 10⁻⁴—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant M700KHomo sapiensadenosylcobalamin—3.76 × 10⁻⁴—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant N366SHomo sapiensadenosylcobalamin—2.19 × 10⁻⁴—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant P86LHomo sapiensadenosylcobalamin—0.003014—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant R694LHomo sapiensadenosylcobalamin—8.41 × 10⁻⁵—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant R694WHomo sapiensadenosylcobalamin—4.59 × 10⁻⁵—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant S344FHomo sapiensadenosylcobalamin—3.64 × 10⁻⁵—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant T387IHomo sapiensadenosylcobalamin—6.66 × 10⁻⁵—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant V633GHomo sapiensadenosylcobalamin—0.001016—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant Y100CHomo sapiensadenosylcobalamin—0.003648—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant Y231NHomo sapiensadenosylcobalamin—0.00602—pH 7.4, 37 °COpen
methylmalonyl-CoA mutase (MUT)variant Y316CHomo sapiensadenosylcobalamin—1.98 × 10⁻⁵—pH 7.4, 37 °COpen