Values CatLog read from this paper
Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase
PMID 14676218doi:10.1074/jbc.m312719200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 17 records (50 values) from this paper: glutaredoxin 2 (Grx2), glutaredoxin 1 (Grx1), thioredoxin reductase 1 (TrxR1) from Homo sapiens, Bos taurus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 1 kcat/Km value marked “calc.” from kcat and Km; no printed kcat/Km was read for that record.
EC 1.8.1.9, EC 1.8.4.2, EC 1.11.1.2
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| glutaredoxin 1 (Grx1) | Homo sapiens | glutathione (reduced) | 293 | 2.16 | 136 | pH 8 | Open record: glutaredoxin 1 (Grx1), glutathione (reduced) |
| glutaredoxin 1 (Grx1) | Homo sapiens | glutathionylated bovine serum albumin | 4.66 | 0.0277 | 168 | pH 7 | Open record: glutaredoxin 1 (Grx1), glutathionylated bovine serum albumin |
| glutaredoxin 1 (Grx1) | Homo sapiens | glutathionylated ribonuclease A | 6.79 | 0.0041 | 1.66 × 10³ | pH 7 | Open record: glutaredoxin 1 (Grx1), glutathionylated ribonuclease A |
| glutaredoxin 1 (Grx1) | Homo sapiens | glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol) | 8.16 | 1.07 | 7.63 | pH 7 | Open record: glutaredoxin 1 (Grx1), glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol) |
| glutaredoxin 1 (Grx1)variant P23S | Homo sapiens | glutathionylated ribonuclease A | 2.25 | 6.1 × 10⁻⁴ | 3.69 × 10³ | pH 7 | Open record: glutaredoxin 1 (Grx1) variant P23S, glutathionylated ribonuclease A |
| glutaredoxin 1 (Grx1)variant P23S | Homo sapiens | glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol) | 1.32 | 0.14 | 9.65 | pH 7 | Open record: glutaredoxin 1 (Grx1) variant P23S, glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol) |
| glutaredoxin 2 (Grx2) | Homo sapiens | glutathione (reduced) | 71.3 | 5.9 | 12.1 | pH 8 | Open record: glutaredoxin 2 (Grx2), glutathione (reduced) |
| glutaredoxin 2 (Grx2) | Homo sapiens | glutathionylated bovine serum albumin | 1.83 | 0.0043 | 427 | pH 7 | Open record: glutaredoxin 2 (Grx2), glutathionylated bovine serum albumin |
| glutaredoxin 2 (Grx2) | Homo sapiens | glutathionylated ribonuclease A | 1.89 | 7.7 × 10⁻⁴ | 2.46 × 10³ | pH 7 | Open record: glutaredoxin 2 (Grx2), glutathionylated ribonuclease A |
| glutaredoxin 2 (Grx2) | Homo sapiens | glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol) | 1.3 | 0.11 | 11.68 | pH 7 | Open record: glutaredoxin 2 (Grx2), glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol) |
| glutaredoxin 2 (Grx2)variant C40S | Homo sapiens | glutathione (reduced) | 37.6 | 0.95 | 39.6 | pH 8 | Open record: glutaredoxin 2 (Grx2) variant C40S, glutathione (reduced) |
| glutaredoxin 2 (Grx2)variant C40S | Homo sapiens | glutathionylated bovine serum albumin | 2.55 | 0.0153 | 167 | pH 7 | Open record: glutaredoxin 2 (Grx2) variant C40S, glutathionylated bovine serum albumin |
| glutaredoxin 2 (Grx2)variant C40S | Homo sapiens | glutathionylated ribonuclease A | 3.71 | 0.0025 | 1.48 × 10³ | pH 7 | Open record: glutaredoxin 2 (Grx2) variant C40S, glutathionylated ribonuclease A |
| glutaredoxin 2 (Grx2)variant C40S | Homo sapiens | glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol) | 4.53 | 1.5 | 3.02 | pH 7 | Open record: glutaredoxin 2 (Grx2) variant C40S, glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol) |
| glutaredoxin 2 (Grx2)variant S38P | Homo sapiens | glutathionylated ribonuclease A | 4.77 | 0.0027 | 1.76 × 10³ | pH 7 | Open record: glutaredoxin 2 (Grx2) variant S38P, glutathionylated ribonuclease A |
| glutaredoxin 2 (Grx2)variant S38P | Homo sapiens | glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol) | 10.64 | 0.55 | 19.35 | pH 7 | Open record: glutaredoxin 2 (Grx2) variant S38P, glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol) |
| thioredoxin reductase 1 (TrxR1) | Bos taurus | human glutaredoxin 2 (oxidized protein) | 13.7 | 0.022 | 620 calc. | pH 7.4, 20 °C | Open record: thioredoxin reductase 1 (TrxR1), human glutaredoxin 2 (oxidized protein) |