EC 1.8.1.9: thioredoxin-disulfide reductase (NADPH)

OxidoreductasesOpen in Browse

CatLog read 117 records for EC 1.8.1.9 from 9 papers, for 9 organisms. Names in these papers: thioredoxin reductase 1 (TrxR1), thioredoxin reductase (EhTRXR), NADPH-dependent thioredoxin reductase 2 (HvNTR2), TGR (thioredoxin and glutathione reductase, formerly TR2) and 7 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 84 records for EC 1.8.1.9 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.8.1.9 in Browse.

Papers

Papers with records for EC 1.8.1.9
Paper	Organisms	Records
Interactions of quinones with thioredoxin reductase: a challenge to the antioxidant role of the mammalian selenoprotein	Rattus norvegicus	28
Entamoeba histolytica thioredoxin reductase: molecular and functional characterization of its atypical properties	Entamoeba histolytica	28
A novel twist on molecular interactions between thioredoxin and nicotinamide adenine dinucleotide phosphate-dependent thioredoxin reductase	Arabidopsis thaliana, Hordeum vulgare	27
Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1	Rattus norvegicus	12
Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems	Mus musculus	8
Biochemical and physiological analyses of NADPH-dependent thioredoxin reductase isozymes in Euglena gracilis	Euglena gracilis	7
Isolation and characterization of thioredoxin and NADPH-dependent thioredoxin reductase from tomato (Solanum lycopersicum)	Solanum lycopersicum	4
Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development	Schistosoma japonicum	2
Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase	Bos taurus	1

Records

Records for EC 1.8.1.9 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
EgNTR1 (NADPH-dependent thioredoxin reductase, small type)	Euglena gracilis	5,5'-dithiobis(2-nitrobenzoic acid)	0.882	2.4	0.377	pH 7	PMID 26025518	Open record: EgNTR1 (NADPH-dependent thioredoxin reductase, small type), 5,5'-dithiobis(2-nitrobenzoic acid)
EgNTR1 (NADPH-dependent thioredoxin reductase, small type)	Euglena gracilis	NADPH	0.592	0.0224	26.5	pH 7	PMID 26025518	Open record: EgNTR1 (NADPH-dependent thioredoxin reductase, small type), NADPH
EgNTR2 (NADPH-dependent thioredoxin reductase, large type)	Euglena gracilis	5,5'-dithiobis(2-nitrobenzoic acid)	10.7	2.5	4.33	pH 7	PMID 26025518	Open record: EgNTR2 (NADPH-dependent thioredoxin reductase, large type), 5,5'-dithiobis(2-nitrobenzoic acid)
EgNTR2 (NADPH-dependent thioredoxin reductase, large type)	Euglena gracilis	NADPH	6.38	0.0056	1.22 × 10³	pH 7	PMID 26025518	Open record: EgNTR2 (NADPH-dependent thioredoxin reductase, large type), NADPH
EgNTRC (NADPH-dependent thioredoxin reductase C)	Euglena gracilis	5,5'-dithiobis(2-nitrobenzoic acid)	1.225	11.9	0.103	pH 7	PMID 26025518	Open record: EgNTRC (NADPH-dependent thioredoxin reductase C), 5,5'-dithiobis(2-nitrobenzoic acid)
EgNTRC (NADPH-dependent thioredoxin reductase C)	Euglena gracilis	NADH	0.198	0.0806	2.48	pH 7	PMID 26025518	Open record: EgNTRC (NADPH-dependent thioredoxin reductase C), NADH
EgNTRC (NADPH-dependent thioredoxin reductase C)	Euglena gracilis	NADPH	0.967	0.0247	39.5	pH 7	PMID 26025518	Open record: EgNTRC (NADPH-dependent thioredoxin reductase C), NADPH
NADPH-dependent thioredoxin reductase (SlNTR)	Solanum lycopersicum	5,5'-dithiobis(2-nitrobenzoic acid)	1.77	0.0186	95	pH 7	PMID 22027005	Open record: NADPH-dependent thioredoxin reductase (SlNTR), 5,5'-dithiobis(2-nitrobenzoic acid)
NADPH-dependent thioredoxin reductase (SlNTR)	Solanum lycopersicum	NADH	0.06	0.1	0.6	pH 7	PMID 22027005	Open record: NADPH-dependent thioredoxin reductase (SlNTR), NADH
NADPH-dependent thioredoxin reductase (SlNTR)	Solanum lycopersicum	NADPH	0.35	0.00235	150	pH 7	PMID 22027005	Open record: NADPH-dependent thioredoxin reductase (SlNTR), NADPH
NADPH-dependent thioredoxin reductase (SlNTR)	Solanum lycopersicum	tomato thioredoxin h (recombinant)	0.38	3.1 × 10⁻⁴	1.23 × 10³	pH 7	PMID 22027005	Open record: NADPH-dependent thioredoxin reductase (SlNTR), tomato thioredoxin h (recombinant)
NADPH-dependent thioredoxin reductase 2 (HvNTR2)	Hordeum vulgare	Arabidopsis thaliana h-type thioredoxin 3	4.8	8 × 10⁻⁴	6 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2), Arabidopsis thaliana h-type thioredoxin 3
NADPH-dependent thioredoxin reductase 2 (HvNTR2)	Hordeum vulgare	Escherichia coli thioredoxin	9.4	0.149	63.1	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2), Escherichia coli thioredoxin
NADPH-dependent thioredoxin reductase 2 (HvNTR2)	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 1	12.1	0.00123	9.84 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2), Hordeum vulgare h-type thioredoxin 1
NADPH-dependent thioredoxin reductase 2 (HvNTR2)	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2	8	0.00117	6.8 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2), Hordeum vulgare h-type thioredoxin 2
NADPH-dependent thioredoxin reductase 2 (HvNTR2)	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2, E86A mutant	5.3	5.7 × 10⁻⁴	9.23 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2), Hordeum vulgare h-type thioredoxin 2, E86A mutant
NADPH-dependent thioredoxin reductase 2 (HvNTR2)	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2, G47P mutant	7.9	0.0014	5.49 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2), Hordeum vulgare h-type thioredoxin 2, G47P mutant
NADPH-dependent thioredoxin reductase 2 (HvNTR2)	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2, I51G mutant	15.9	0.0155	1.03 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2), Hordeum vulgare h-type thioredoxin 2, I51G mutant
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant G222D/A223G/G224E	Hordeum vulgare	Arabidopsis thaliana h-type thioredoxin 3	5	5.2 × 10⁻⁴	9.62 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant G222D/A223G/G224E, Arabidopsis thaliana h-type thioredoxin 3
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant G222D/A223G/G224E	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2	7.9	0.00146	5.41 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant G222D/A223G/G224E, Hordeum vulgare h-type thioredoxin 2
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant G225R/G226D	Hordeum vulgare	Arabidopsis thaliana h-type thioredoxin 3	5	6.7 × 10⁻⁴	7.46 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant G225R/G226D, Arabidopsis thaliana h-type thioredoxin 3
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant G225R/G226D	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2	8.1	0.00128	6.33 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant G225R/G226D, Hordeum vulgare h-type thioredoxin 2
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant G225R/G226D/P227V	Hordeum vulgare	Arabidopsis thaliana h-type thioredoxin 3	3.9	7.3 × 10⁻⁴	5.34 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant G225R/G226D/P227V, Arabidopsis thaliana h-type thioredoxin 3
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant G225R/G226D/P227V	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2	1.8	0.00105	1.71 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant G225R/G226D/P227V, Hordeum vulgare h-type thioredoxin 2
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant M43A	Hordeum vulgare	Arabidopsis thaliana h-type thioredoxin 3	14.8	0.0141	1.05 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant M43A, Arabidopsis thaliana h-type thioredoxin 3
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant M43A	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2	11.4	0.016	713	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant M43A, Hordeum vulgare h-type thioredoxin 2
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant N139A	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2	4.2	6.8 × 10⁻⁴	6.18 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant N139A, Hordeum vulgare h-type thioredoxin 2
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant N139A	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2, E86A mutant	4.2	4.1 × 10⁻⁴	1.02 × 10⁴	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant N139A, Hordeum vulgare h-type thioredoxin 2, E86A mutant
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant N45A/D46A	Hordeum vulgare	Arabidopsis thaliana h-type thioredoxin 3	10.7	0.0042	2.55 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant N45A/D46A, Arabidopsis thaliana h-type thioredoxin 3
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant N45A/D46A	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2	7.3	0.0022	3.3 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant N45A/D46A, Hordeum vulgare h-type thioredoxin 2
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant R140A	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2	5.1	0.00343	1.49 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant R140A, Hordeum vulgare h-type thioredoxin 2
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant R140A	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2, E86A mutant	2.6	0.0016	1.63 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant R140A, Hordeum vulgare h-type thioredoxin 2, E86A mutant
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant W42A	Hordeum vulgare	Arabidopsis thaliana h-type thioredoxin 3	10.4	0.0024	4.24 × 10³	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant W42A, Arabidopsis thaliana h-type thioredoxin 3
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant W42A	Hordeum vulgare	Hordeum vulgare h-type thioredoxin 2	10.4	0.0457	228	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant W42A, Hordeum vulgare h-type thioredoxin 2
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant W42A/M43A	Hordeum vulgare	Arabidopsis thaliana h-type thioredoxin 3	11	0.0305	361	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant W42A/M43A, Arabidopsis thaliana h-type thioredoxin 3
NADPH-dependent thioredoxin reductase 2 (HvNTR2)variant Δ42–47	Hordeum vulgare	Arabidopsis thaliana h-type thioredoxin 3	15.3	0.0543	282	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase 2 (HvNTR2) variant Δ42–47, Arabidopsis thaliana h-type thioredoxin 3
NADPH-dependent thioredoxin reductase B (AtNTR-B)	Arabidopsis thaliana	Arabidopsis thaliana h-type thioredoxin 3	5.9	4.8 × 10⁻⁴	1.23 × 10⁴	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase B (AtNTR-B), Arabidopsis thaliana h-type thioredoxin 3
NADPH-dependent thioredoxin reductase B (AtNTR-B)	Arabidopsis thaliana	Hordeum vulgare h-type thioredoxin 2	8.5	0.06	140	pH 7.5	PMID 24123219	Open record: NADPH-dependent thioredoxin reductase B (AtNTR-B), Hordeum vulgare h-type thioredoxin 2
SjTGR	Schistosoma japonicum	5,5'-dithiobis(2-nitrobenzoic acid)	23.52	0.1169	201.2	pH 7, 25 °C	PMID 42030356	Open record: SjTGR, 5,5'-dithiobis(2-nitrobenzoic acid)
SjTGRvariant T594V	Schistosoma japonicum	5,5'-dithiobis(2-nitrobenzoic acid)	20.70	0.1188	174.2	pH 7, 25 °C	PMID 42030356	Open record: SjTGR variant T594V, 5,5'-dithiobis(2-nitrobenzoic acid)
TGR (thioredoxin and glutathione reductase, formerly TR2)	Mus musculus	5,5'-dithiobis(2-nitrobenzoic acid)	6.53	0.0147	444 calc.	25 °C	PMID 11259642	Open record: TGR (thioredoxin and glutathione reductase, formerly TR2), 5,5'-dithiobis(2-nitrobenzoic acid)
TGR (thioredoxin and glutathione reductase, formerly TR2)	Mus musculus	beta-hydroxyethyl disulfide	1.2	0.0452	27 calc.	25 °C	PMID 11259642	Open record: TGR (thioredoxin and glutathione reductase, formerly TR2), beta-hydroxyethyl disulfide
TGR (thioredoxin and glutathione reductase, formerly TR2)	Mus musculus	Escherichia coli thioredoxin	5.7	0.003	1.9 × 10³ calc.	25 °C	PMID 11259642	Open record: TGR (thioredoxin and glutathione reductase, formerly TR2), Escherichia coli thioredoxin
TGR (thioredoxin and glutathione reductase, formerly TR2)	Mus musculus	NADPH	—	0.0107	—	25 °C	PMID 11259642	Open record: TGR (thioredoxin and glutathione reductase, formerly TR2), NADPH
TGR (thioredoxin and glutathione reductase, formerly TR2)	Mus musculus	oxidized glutathione (glutathione disulfide)	1.57	0.00884	180 calc.	25 °C	PMID 11259642	Open record: TGR (thioredoxin and glutathione reductase, formerly TR2), oxidized glutathione (glutathione disulfide)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	1-chloro-2,4-dinitrobenzene	4.97	0.105	47	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), 1-chloro-2,4-dinitrobenzene
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	2,5-di-tert-butyl-1,4-benzoquinone	0.95	0.007	140	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), 2,5-di-tert-butyl-1,4-benzoquinone
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	2-methyl-1,4-benzoquinone	9.47	0.092	100	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), 2-methyl-1,4-benzoquinone
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	5,5'-dithiobis(2-nitrobenzoic acid)0.3 mM NADPH; cosubstrate NADPH (0.3 mM)	0.25	1.1	0.23	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), 5,5'-dithiobis(2-nitrobenzoic acid)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	5,5'-dithiobis(2-nitrobenzoic acid)0.4 mM NADH; cosubstrate NADH (0.4 mM)	0.23	1.4	0.17	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), 5,5'-dithiobis(2-nitrobenzoic acid)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	Entamoeba histolytica thioredoxin EhTRX41 (oxidized)0.3 mM NADPH; cosubstrate NADPH (0.3 mM)	2.2	0.0036	600	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), Entamoeba histolytica thioredoxin EhTRX41 (oxidized)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	Entamoeba histolytica thioredoxin EhTRX41 (oxidized)0.4 mM NADH; cosubstrate NADH (0.4 mM)	2.03	0.0023	880	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), Entamoeba histolytica thioredoxin EhTRX41 (oxidized)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	Entamoeba histolytica thioredoxin EhTRX8 (oxidized)0.3 mM NADPH; cosubstrate NADPH (0.3 mM)	2.7	0.0028	950	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), Entamoeba histolytica thioredoxin EhTRX8 (oxidized)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	Entamoeba histolytica thioredoxin EhTRX8 (oxidized)0.4 mM NADH; cosubstrate NADH (0.4 mM)	2.58	0.0029	890	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), Entamoeba histolytica thioredoxin EhTRX8 (oxidized)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	Escherichia coli thioredoxin (oxidized)thioredoxin reductase assay; 0.3 mM NADPH	1.25	0.0047	260	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), Escherichia coli thioredoxin (oxidized)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	Escherichia coli thioredoxin (oxidized)thioredoxin reductase assay; 0.4 mM NADH	0.5	0.0062	75	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), Escherichia coli thioredoxin (oxidized)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	Escherichia coli thioredoxin (oxidized)redox potential determination; NADPH oxidation at 340 nm	—	—	295	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), Escherichia coli thioredoxin (oxidized)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	Escherichia coli thioredoxin (reduced)	—	—	118	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), Escherichia coli thioredoxin (reduced)
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	methyl viologen	2.68	0.184	14	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), methyl viologen
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	methylene blue	3.5	0.02	170	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), methylene blue
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	NADHcosubstrate DTNB (5 mM)	0.2	0.023	84	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), NADH
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	NADHH2O2 production by ferrithiocyanate method; 300 μM NAD(P)H	0.37	—	—	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), NADH
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	NADP+	—	—	17	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), NADP+
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	NADPHDTNB (5 mM)	0.25	0.0018	140	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), NADPH
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	NADPHredox potential determination; NADPH oxidation at 340 nm	—	—	158	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), NADPH
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	NADPHH2O2 production by ferrithiocyanate method; 300 μM NAD(P)H	0.37	—	—	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), NADPH
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	potassium ferricyanide (hexacyanoferrate(III))	6.2	0.293	21	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), potassium ferricyanide (hexacyanoferrate(III))
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	S-nitrosocysteinereduction	2.53	0.452	5.6	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), S-nitrosocysteine
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	S-nitrosocysteinereduction in the presence of 5 μM EcTRX	—	—	1.2	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), S-nitrosocysteine
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	S-nitrosocysteinereduction in the presence of 5 μM EhTRX41	—	—	14	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), S-nitrosocysteine
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	S-nitrosoglutathionereduction	0.38	0.342	1.1	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), S-nitrosoglutathione
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	S-nitrosoglutathionereduction in the presence of 5 μM EcTRX	—	—	11	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), S-nitrosoglutathione
thioredoxin reductase (EhTRXR)	Entamoeba histolytica	S-nitrosoglutathionereduction in the presence of 5 μM EhTRX41	—	—	11	pH 7, 30 °C	PMID 22967759	Open record: thioredoxin reductase (EhTRXR), S-nitrosoglutathione
thioredoxin reductase 1 (TrxR1)	Bos taurus	human glutaredoxin 2 (oxidized protein)	13.7	0.022	620 calc.	pH 7.4, 20 °C	PMID 14676218	Open record: thioredoxin reductase 1 (TrxR1), human glutaredoxin 2 (oxidized protein)
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	1,4-Benzoquinone	4.8	—	390	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 1,4-Benzoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	1,4-Naphthoquinone	4.6	—	440	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 1,4-Naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2,3-Dichloro-1,4-naphthoquinone	9.6	—	6.1 × 10³	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2,3-Dichloro-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2,5-diaziridinyl-1,4-benzoquinone	0.15	—	5.5	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2,5-diaziridinyl-1,4-benzoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone	0.13	—	1	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2,5-Dimethyl-1,4-benzoquinone	1.8	—	190	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2,5-Dimethyl-1,4-benzoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone	0.16	—	4.4	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2-Hydroxy-1,4-naphthoquinone	0.04	—	0.7	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2-Hydroxy-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2-Methyl-1,4-benzoquinone	2.8	—	70	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2-Methyl-1,4-benzoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2-Methyl-1,4-naphthoquinone	1.5	—	12	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2-Methyl-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2-methyl-1,4-naphthoquinone	0.18	—	1.4	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2-methyl-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2-Methyl-3-glutathionyl-5-hydroxy-1,4-naphthoquinone	0.11	—	7	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2-Methyl-3-glutathionyl-5-hydroxy-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	2-Methyl-5-hydroxy-1,4-naphthoquinone	3.2	—	21	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 2-Methyl-5-hydroxy-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	5,5'-dithiobis(2-nitrobenzoic acid)	20.6	—	145	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 5,5'-dithiobis(2-nitrobenzoic acid)
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	5,5'-dithiobis(2-nitrobenzoic acid)	70.3	0.094	748	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1), 5,5'-dithiobis(2-nitrobenzoic acid)
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	5,8-Dihydroxy-1,4-naphthoquinone	7.4	—	230	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 5,8-Dihydroxy-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	5-hydroxy-1,4-naphthoquinonesteady-state NADPH:quinone reductase assay; aerobic	4.9	—	2.1 × 10³	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 5-hydroxy-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	5-hydroxy-1,4-naphthoquinonestopped-flow; parameters from the 0-5 s interval	4.5	—	1.6 × 10³	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 5-hydroxy-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	5-hydroxy-1,4-naphthoquinoneNADPH:quinone reductase assay (NADPH oxidation)	3.5	—	2.5 × 10³	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 5-hydroxy-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	5-hydroxy-1,4-naphthoquinone	24.1	0.00227	10,617	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1), 5-hydroxy-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	9,10-phenanthrenequinonesteady-state NADPH:quinone reductase assay; aerobic	17.3	—	1.9 × 10³	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 9,10-phenanthrenequinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	9,10-phenanthrenequinoneNADPH:quinone reductase assay (NADPH oxidation)	0.25	—	5.6	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), 9,10-phenanthrenequinone
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	Chlamydomonas reinhardtii thioredoxin, oxidized (disulfide) formkcat per active site	20	—	1.06 × 10³	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), Chlamydomonas reinhardtii thioredoxin, oxidized (disulfide) form
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	Chlamydomonas reinhardtii thioredoxin, oxidized (disulfide) form	—	0.019	—	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), Chlamydomonas reinhardtii thioredoxin, oxidized (disulfide) form
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	Chlamydomonas reinhardtii thioredoxin, reduced (dithiol) form	—	—	2.18 × 10³	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), Chlamydomonas reinhardtii thioredoxin, reduced (dithiol) form
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	human thioredoxin	94.17	0.00143	65,943	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1), human thioredoxin
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	lipoamide	23.67	2.89	8.2	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1), lipoamide
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	NADP+	16.5	—	415	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), NADP+
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	NADPHNADPH:DTNB reduction; TNB formation at 412 nm	—	—	3.42 × 10³	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), NADPH
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	NADPHNADPH:C. reinhardtii thioredoxin reduction	—	—	3.05 × 10³	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), NADPH
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	NADPHNADPH:9,10-phenanthrene quinone reductase reaction	—	—	2.8 × 10³	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), NADPH
thioredoxin reductase 1 (TrxR1)	Rattus norvegicus	Tetramethyl-1,4-benzoquinone	0.12	—	0.6	pH 7, 25 °C	PMID 14604985	Open record: thioredoxin reductase 1 (TrxR1), Tetramethyl-1,4-benzoquinone
thioredoxin reductase 1 (TrxR1)variant Y116I	Rattus norvegicus	5,5'-dithiobis(2-nitrobenzoic acid)	49.87	0.0971	513	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1) variant Y116I, 5,5'-dithiobis(2-nitrobenzoic acid)
thioredoxin reductase 1 (TrxR1)variant Y116I	Rattus norvegicus	5-hydroxy-1,4-naphthoquinone	174.3	0.02374	7343	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1) variant Y116I, 5-hydroxy-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)variant Y116I	Rattus norvegicus	human thioredoxin	40.98	9.9 × 10⁻⁴	41,448	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1) variant Y116I, human thioredoxin
thioredoxin reductase 1 (TrxR1)variant Y116I	Rattus norvegicus	lipoamide	27.62	3.68	7.515	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1) variant Y116I, lipoamide
thioredoxin reductase 1 (TrxR1)variant Y116T	Rattus norvegicus	5,5'-dithiobis(2-nitrobenzoic acid)	47.72	0.0906	527	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1) variant Y116T, 5,5'-dithiobis(2-nitrobenzoic acid)
thioredoxin reductase 1 (TrxR1)variant Y116T	Rattus norvegicus	5-hydroxy-1,4-naphthoquinone	52.75	0.00698	7557	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1) variant Y116T, 5-hydroxy-1,4-naphthoquinone
thioredoxin reductase 1 (TrxR1)variant Y116T	Rattus norvegicus	human thioredoxin	44.85	0.00106	42,152	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1) variant Y116T, human thioredoxin
thioredoxin reductase 1 (TrxR1)variant Y116T	Rattus norvegicus	lipoamide	31.17	5.59	5.58	pH 7.5, 20 °C	PMID 19054767	Open record: thioredoxin reductase 1 (TrxR1) variant Y116T, lipoamide
TR1 (thioredoxin reductase 1, cytosolic TR)	Mus musculus	5,5'-dithiobis(2-nitrobenzoic acid)	86.3	0.212	407 calc.	25 °C	PMID 11259642	Open record: TR1 (thioredoxin reductase 1, cytosolic TR), 5,5'-dithiobis(2-nitrobenzoic acid)
TR1 (thioredoxin reductase 1, cytosolic TR)	Mus musculus	Escherichia coli thioredoxin	9.8	0.00473	2.1 × 10³ calc.	25 °C	PMID 11259642	Open record: TR1 (thioredoxin reductase 1, cytosolic TR), Escherichia coli thioredoxin
TR1 (thioredoxin reductase 1, cytosolic TR)	Mus musculus	NADPH	—	0.0196	—	25 °C	PMID 11259642	Open record: TR1 (thioredoxin reductase 1, cytosolic TR), NADPH