EC 1.8.4.2: protein-disulfide reductase (glutathione)

OxidoreductasesOpen in Browse

CatLog read 16 records for EC 1.8.4.2 from 1 paper, for 1 organism. Names in these papers: glutaredoxin 2 (Grx2), glutaredoxin 1 (Grx1).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 9 records for EC 1.8.4.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.8.4.2 in Browse.

Papers

Papers with records for EC 1.8.4.2
Paper	Organisms	Records
Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase	Homo sapiens	16

Records

Records for EC 1.8.4.2 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
glutaredoxin 1 (Grx1)	Homo sapiens	glutathione (reduced)	293	2.16	136	pH 8	PMID 14676218	Open record: glutaredoxin 1 (Grx1), glutathione (reduced)
glutaredoxin 1 (Grx1)	Homo sapiens	glutathionylated bovine serum albumin	4.66	0.0277	168	pH 7	PMID 14676218	Open record: glutaredoxin 1 (Grx1), glutathionylated bovine serum albumin
glutaredoxin 1 (Grx1)	Homo sapiens	glutathionylated ribonuclease A	6.79	0.0041	1.66 × 10³	pH 7	PMID 14676218	Open record: glutaredoxin 1 (Grx1), glutathionylated ribonuclease A
glutaredoxin 1 (Grx1)	Homo sapiens	glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol)	8.16	1.07	7.63	pH 7	PMID 14676218	Open record: glutaredoxin 1 (Grx1), glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol)
glutaredoxin 1 (Grx1)variant P23S	Homo sapiens	glutathionylated ribonuclease A	2.25	6.1 × 10⁻⁴	3.69 × 10³	pH 7	PMID 14676218	Open record: glutaredoxin 1 (Grx1) variant P23S, glutathionylated ribonuclease A
glutaredoxin 1 (Grx1)variant P23S	Homo sapiens	glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol)	1.32	0.14	9.65	pH 7	PMID 14676218	Open record: glutaredoxin 1 (Grx1) variant P23S, glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol)
glutaredoxin 2 (Grx2)	Homo sapiens	glutathione (reduced)	71.3	5.9	12.1	pH 8	PMID 14676218	Open record: glutaredoxin 2 (Grx2), glutathione (reduced)
glutaredoxin 2 (Grx2)	Homo sapiens	glutathionylated bovine serum albumin	1.83	0.0043	427	pH 7	PMID 14676218	Open record: glutaredoxin 2 (Grx2), glutathionylated bovine serum albumin
glutaredoxin 2 (Grx2)	Homo sapiens	glutathionylated ribonuclease A	1.89	7.7 × 10⁻⁴	2.46 × 10³	pH 7	PMID 14676218	Open record: glutaredoxin 2 (Grx2), glutathionylated ribonuclease A
glutaredoxin 2 (Grx2)	Homo sapiens	glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol)	1.3	0.11	11.68	pH 7	PMID 14676218	Open record: glutaredoxin 2 (Grx2), glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol)
glutaredoxin 2 (Grx2)variant C40S	Homo sapiens	glutathione (reduced)	37.6	0.95	39.6	pH 8	PMID 14676218	Open record: glutaredoxin 2 (Grx2) variant C40S, glutathione (reduced)
glutaredoxin 2 (Grx2)variant C40S	Homo sapiens	glutathionylated bovine serum albumin	2.55	0.0153	167	pH 7	PMID 14676218	Open record: glutaredoxin 2 (Grx2) variant C40S, glutathionylated bovine serum albumin
glutaredoxin 2 (Grx2)variant C40S	Homo sapiens	glutathionylated ribonuclease A	3.71	0.0025	1.48 × 10³	pH 7	PMID 14676218	Open record: glutaredoxin 2 (Grx2) variant C40S, glutathionylated ribonuclease A
glutaredoxin 2 (Grx2)variant C40S	Homo sapiens	glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol)	4.53	1.5	3.02	pH 7	PMID 14676218	Open record: glutaredoxin 2 (Grx2) variant C40S, glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol)
glutaredoxin 2 (Grx2)variant S38P	Homo sapiens	glutathionylated ribonuclease A	4.77	0.0027	1.76 × 10³	pH 7	PMID 14676218	Open record: glutaredoxin 2 (Grx2) variant S38P, glutathionylated ribonuclease A
glutaredoxin 2 (Grx2)variant S38P	Homo sapiens	glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol)	10.64	0.55	19.35	pH 7	PMID 14676218	Open record: glutaredoxin 2 (Grx2) variant S38P, glutathionylated β-mercaptoethanol (mixed disulfide of glutathione and 2-mercaptoethanol)