CatLogenzyme kinetics catalog

Values CatLog read from this paper

Structure and kinetic properties of human d-aspartate oxidase, the enzyme-controlling d-aspartate levels in brain

PMID 31914658doi:10.1096/fj.201901703rOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 25 records (70 values) from this paper: D-aspartate oxidase (hDASPO, DDO-1 isoform) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 1 kcat/Km value marked “calc.” from kcat and Km; no printed kcat/Km was read for that record.

EC 1.4.3.1

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
D-aspartate oxidase (hDASPO, DDO-1 isoform)Homo sapiensD-asparagine8.3670.12pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)Homo sapiensD-aspartateDalziel analysis; cosubstrate O22297.232 calc.pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)Homo sapiensD-aspartateoxygen consumption; Hansatech oxygen electrode; 40 µM FAD81.31.0577.4pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)Homo sapiensD-glutamate11.331.50.36pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)Homo sapiensD-histidine1.2960.011pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)Homo sapiensD-proline1.23390.003pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)Homo sapiensdioxygen—0.34—pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)Homo sapiensN-methyl-D-aspartateSupplementary Table 273.62.7626.7pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)Homo sapiensN-methyl-D-aspartateSupplementary Table 473.22.7526.6pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant C141S/C143SHomo sapiensD-aspartate32.81.620.5pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant C141Y/C143G (hDASPO*)Homo sapiensD-aspartate68.61.353.1pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant C141Y/C143G/C328SHomo sapiensD-aspartate72.91.259.3pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant C269SHomo sapiensD-aspartate85.91.368.2pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant C269S/C328SHomo sapiensD-aspartate69.72.528pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant C29S/C269S/C328SHomo sapiensD-aspartate69.91.839.7pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant C328SHomo sapiensD-aspartate68.9168.2pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant C328VHomo sapiensD-aspartate80.6182.2pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant H54AHomo sapiensD-asparagine29.1——pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant H54AHomo sapiensD-aspartate65.21.4545pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant H54AHomo sapiensD-glutamate11.259.40.19pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant H54AHomo sapiensN-methyl-D-aspartate1141.8960.3pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant R237AHomo sapiensD-asparagine11.2590.19pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant R237AHomo sapiensD-aspartate55.722.22.5pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant R237AHomo sapiensD-glutamate9.843.30.23pH 8.3, 25 °COpen
D-aspartate oxidase (hDASPO, DDO-1 isoform)variant R237AHomo sapiensN-methyl-D-aspartate65.511.35.8pH 8.3, 25 °COpen