Values CatLog read from this paper
Design of reverse transcriptase-specific nucleosides to visualize early steps of HIV-1 replication by click labeling
PMID 31201270doi:10.1074/jbc.ra118.007185Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 9 records (27 values) from this paper: HIV-1 reverse transcriptase from Human immunodeficiency virus type 1.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| HIV-1 reverse transcriptase | Human immunodeficiency virus type 1 | ((2R,3S,5R)-3-hydroxy-5-(6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateDNA template; DNA | 0.0295 | 0.00317 | 9.3 | pH 8, 37 °C | Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-3-hydroxy-5-(6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate |
| HIV-1 reverse transcriptase | Human immunodeficiency virus type 1 | ((2R,3S,5R)-3-hydroxy-5-(6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateRNA template; RNA | 0.047 | 0.00324 | 14.5 | pH 8, 37 °C | Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-3-hydroxy-5-(6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate |
| HIV-1 reverse transcriptase | Human immunodeficiency virus type 1 | ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateDNA template; reaction time 40 s; DNA | 0.0317 | 0.0016 | 19.8 | pH 8, 37 °C | Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate |
| HIV-1 reverse transcriptase | Human immunodeficiency virus type 1 | ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateRNA template; reaction time 1 min; RNA | 0.0422 | 0.00202 | 20.8 | pH 8, 37 °C | Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate |
| HIV-1 reverse transcriptase | Human immunodeficiency virus type 1 | ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateDNA template; reaction time 40 s; DNA | 0.028 | 0.00389 | 7.2 | pH 8, 37 °C | Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate |
| HIV-1 reverse transcriptase | Human immunodeficiency virus type 1 | ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateRNA template; reaction time 30 s; RNA | 0.0545 | 0.00822 | 6.7 | pH 8, 37 °C | Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate |
| HIV-1 reverse transcriptase | Human immunodeficiency virus type 1 | ((2R,3S,5R)-5-(6-amino-8-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate | 0.0195 | 0.01365 | 1.5 | pH 8, 37 °C | Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-5-(6-amino-8-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate |
| HIV-1 reverse transcriptase | Human immunodeficiency virus type 1 | 2'-deoxyadenosine 5'-triphosphateDNA template; reaction time 40 s; DNA | 0.0298 | 8.2 × 10⁻⁴ | 36.3 | pH 8, 37 °C | Open record: HIV-1 reverse transcriptase, 2'-deoxyadenosine 5'-triphosphate |
| HIV-1 reverse transcriptase | Human immunodeficiency virus type 1 | 2'-deoxyadenosine 5'-triphosphateRNA template; RNA | 0.0672 | 0.00133 | 50.5 | pH 8, 37 °C | Open record: HIV-1 reverse transcriptase, 2'-deoxyadenosine 5'-triphosphate |