EC 2.7.7.49: RNA-directed DNA polymerase

TransferasesOpen in Browse

CatLog read 98 records for EC 2.7.7.49 from 4 papers, for 3 organisms. Names in these papers: HIV-1 reverse transcriptase, HIV-1 RT (reverse transcriptase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 21 records for EC 2.7.7.49 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.7.49 in Browse.

Papers

Papers with records for EC 2.7.7.49
Paper	Organisms	Records
Nucleotide specificity of HIV-1 reverse transcriptases with amino acid substitutions affecting Ala-114	HIV-1	43
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses	Human immunodeficiency virus type 1 (HIV-1)	36
Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs	HIV-1	10
Design of reverse transcriptase-specific nucleosides to visualize early steps of HIV-1 replication by click labeling	Human immunodeficiency virus type 1	9

Records

Records for EC 2.7.7.49 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
HIV-1 reverse transcriptase	HIV-1	2'-deoxyadenosine-5'-triphosphate	17	—	—	pH 7.5, 37 °C	PMID 21914723	Open record: HIV-1 reverse transcriptase, 2'-deoxyadenosine-5'-triphosphate
HIV-1 reverse transcriptase	HIV-1	2'-deoxyguanosine-5'-triphosphate	17.3	—	—	pH 7.5, 37 °C	PMID 21914723	Open record: HIV-1 reverse transcriptase, 2'-deoxyguanosine-5'-triphosphate
HIV-1 reverse transcriptase	HIV-1	3'-azido-2',3'-dideoxy-2,6-diaminopurine-5'-triphosphatethymine (Table 1 footnote a, 'A' analog T/P)	14	—	—	pH 7.5, 37 °C	PMID 21914723	Open record: HIV-1 reverse transcriptase, 3'-azido-2',3'-dideoxy-2,6-diaminopurine-5'-triphosphate
HIV-1 reverse transcriptase	HIV-1	3'-azido-2',3'-dideoxy-2,6-diaminopurine-5'-triphosphatecytosine (Table 1 footnote d, 'G' analog T/P)	0.16	—	—	pH 7.5, 37 °C	PMID 21914723	Open record: HIV-1 reverse transcriptase, 3'-azido-2',3'-dideoxy-2,6-diaminopurine-5'-triphosphate
HIV-1 reverse transcriptase	HIV-1	3'-azido-2',3'-dideoxy-2-amino-6-chloropurine-5'-triphosphatethymine (Table 1 footnote a, 'A' analog T/P)	2.7	—	—	pH 7.5, 37 °C	PMID 21914723	Open record: HIV-1 reverse transcriptase, 3'-azido-2',3'-dideoxy-2-amino-6-chloropurine-5'-triphosphate
HIV-1 reverse transcriptase	HIV-1	3'-azido-2',3'-dideoxy-2-amino-6-chloropurine-5'-triphosphatecytosine (Table 1 footnote d, 'G' analog T/P)	0.37	—	—	pH 7.5, 37 °C	PMID 21914723	Open record: HIV-1 reverse transcriptase, 3'-azido-2',3'-dideoxy-2-amino-6-chloropurine-5'-triphosphate
HIV-1 reverse transcriptase	HIV-1	3'-azido-2',3'-dideoxy-2-amino-6-methoxypurine-5'-triphosphatethymine (Table 1 footnote a, 'A' analog T/P)	2.8	—	—	pH 7.5, 37 °C	PMID 21914723	Open record: HIV-1 reverse transcriptase, 3'-azido-2',3'-dideoxy-2-amino-6-methoxypurine-5'-triphosphate
HIV-1 reverse transcriptase	HIV-1	3'-azido-2',3'-dideoxy-2-amino-6-methoxypurine-5'-triphosphatecytosine (Table 1 footnote d, 'G' analog T/P)	0.22	—	—	pH 7.5, 37 °C	PMID 21914723	Open record: HIV-1 reverse transcriptase, 3'-azido-2',3'-dideoxy-2-amino-6-methoxypurine-5'-triphosphate
HIV-1 reverse transcriptase	HIV-1	3'-azido-2',3'-dideoxy-2-amino-6-N-allylaminopurine-5'-triphosphate	2.1	—	—	pH 7.5, 37 °C	PMID 21914723	Open record: HIV-1 reverse transcriptase, 3'-azido-2',3'-dideoxy-2-amino-6-N-allylaminopurine-5'-triphosphate
HIV-1 reverse transcriptase	HIV-1	3'-azido-2',3'-dideoxyadenosine-5'-triphosphate	14	—	—	pH 7.5, 37 °C	PMID 21914723	Open record: HIV-1 reverse transcriptase, 3'-azido-2',3'-dideoxyadenosine-5'-triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1	((2R,3S,5R)-3-hydroxy-5-(6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateDNA template; DNA	0.0295	0.00317	9.3	pH 8, 37 °C	PMID 31201270	Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-3-hydroxy-5-(6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1	((2R,3S,5R)-3-hydroxy-5-(6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateRNA template; RNA	0.047	0.00324	14.5	pH 8, 37 °C	PMID 31201270	Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-3-hydroxy-5-(6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1	((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateDNA template; reaction time 40 s; DNA	0.0317	0.0016	19.8	pH 8, 37 °C	PMID 31201270	Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1	((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateRNA template; reaction time 1 min; RNA	0.0422	0.00202	20.8	pH 8, 37 °C	PMID 31201270	Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1	((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateDNA template; reaction time 40 s; DNA	0.028	0.00389	7.2	pH 8, 37 °C	PMID 31201270	Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1	((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphateRNA template; reaction time 30 s; RNA	0.0545	0.00822	6.7	pH 8, 37 °C	PMID 31201270	Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1	((2R,3S,5R)-5-(6-amino-8-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate	0.0195	0.01365	1.5	pH 8, 37 °C	PMID 31201270	Open record: HIV-1 reverse transcriptase, ((2R,3S,5R)-5-(6-amino-8-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1	2'-deoxyadenosine 5'-triphosphateDNA template; reaction time 40 s; DNA	0.0298	8.2 × 10⁻⁴	36.3	pH 8, 37 °C	PMID 31201270	Open record: HIV-1 reverse transcriptase, 2'-deoxyadenosine 5'-triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1	2'-deoxyadenosine 5'-triphosphateRNA template; RNA	0.0672	0.00133	50.5	pH 8, 37 °C	PMID 31201270	Open record: HIV-1 reverse transcriptase, 2'-deoxyadenosine 5'-triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.327	5 × 10⁻⁴	653	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.212	0.00114	187	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptase	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	2.6	0.00472	552	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant D67N/K70R/T215Y/K219Q	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.332	8.6 × 10⁻⁴	385	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant D67N/K70R/T215Y/K219Q, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant D67N/K70R/T215Y/K219Q	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.275	0.00168	163	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant D67N/K70R/T215Y/K219Q, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant D67N/K70R/T215Y/K219Q	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	1.95	0.006	325	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant D67N/K70R/T215Y/K219Q, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.532	5 × 10⁻⁴	1057	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K103N, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.297	8.2 × 10⁻⁴	362	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K103N, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	1.9	0.00218	875	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K103N, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.258	0.0011	235	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.235	0.00149	158	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	0.95	0.00306	312	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R/K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.507	0.00128	395	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R/K103N, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R/K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.645	9.6 × 10⁻⁴	675	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R/K103N, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R/K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	3.38	0.00333	1018	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R/K103N, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R/K103N/Q151M	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.31	0.00149	207	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R/K103N/Q151M, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R/K103N/Q151M	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.382	6.5 × 10⁻⁴	588	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R/K103N/Q151M, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R/K103N/Q151M	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	3.28	0.00439	748	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R/K103N/Q151M, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R/Q151M	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.215	9.5 × 10⁻⁴	227	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R/Q151M, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R/Q151M	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.385	0.00118	325	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R/Q151M, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant K65R/Q151M	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	2.45	0.0044	555	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant K65R/Q151M, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant L74V	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.337	4.5 × 10⁻⁴	755	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant L74V, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant L74V	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.312	0.00134	233	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant L74V, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant L74V	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	1.2	0.00273	442	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant L74V, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant L74V/K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.21	2.1 × 10⁻⁴	978	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant L74V/K103N, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant L74V/K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.193	3 × 10⁻⁴	648	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant L74V/K103N, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant L74V/K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	2.02	0.0024	842	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant L74V/K103N, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant M184V	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.25	7.3 × 10⁻⁴	343	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant M184V, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant M184V	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.392	0.00114	343	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant M184V, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant M184V	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	2.05	0.0047	437	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant M184V, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant Q151M	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.227	7.3 × 10⁻⁴	310	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant Q151M, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant Q151M	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.245	4 × 10⁻⁴	617	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant Q151M, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant Q151M	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	2.77	0.00578	478	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant Q151M, 2'-deoxythymidine 5'-triphosphate
HIV-1 reverse transcriptasevariant Q151M/K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxycytidine 5'-triphosphate	0.145	7.5 × 10⁻⁴	193	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant Q151M/K103N, 2'-deoxycytidine 5'-triphosphate
HIV-1 reverse transcriptasevariant Q151M/K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxyguanosine 5'-triphosphate	0.218	5.5 × 10⁻⁴	398	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant Q151M/K103N, 2'-deoxyguanosine 5'-triphosphate
HIV-1 reverse transcriptasevariant Q151M/K103N	Human immunodeficiency virus type 1 (HIV-1)	2'-deoxythymidine 5'-triphosphate	2.7	0.00388	697	pH 7.8, 37 °C	PMID 12651859	Open record: HIV-1 reverse transcriptase variant Q151M/K103N, 2'-deoxythymidine 5'-triphosphate
HIV-1 RT (reverse transcriptase)	HIV-1	3'-azido-3'-deoxythymidine triphosphate	0.0605	0.00242	25.15	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), 3'-azido-3'-deoxythymidine triphosphate
HIV-1 RT (reverse transcriptase)	HIV-1	dATPtemplate-primer D2cg/20PG5cg (38/20-mer DNA-DNA)	0.0542	4.7 × 10⁻⁵	1160	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), dATP
HIV-1 RT (reverse transcriptase)	HIV-1	dATPtemplate-primer D2-47/PG5-25 (47/25-mer DNA-DNA)	3 × 10⁻⁴	—	—	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), dATP
HIV-1 RT (reverse transcriptase)	HIV-1	dCTPtemplate-primer D38G/25PGG (DNA-DNA); D38G/25PGG (DNA-DNA)	0.0498	1 × 10⁻⁴	495.7	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), dCTP
HIV-1 RT (reverse transcriptase)	HIV-1	dCTPtemplate-primer D2-47/PG5-25 (47/25-mer DNA-DNA)	0.0273	1.693	0.0162	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), dCTP
HIV-1 RT (reverse transcriptase)	HIV-1	ddATP	0.0388	6.36 × 10⁻⁴	61.2	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), ddATP
HIV-1 RT (reverse transcriptase)	HIV-1	ddCTP	0.0222	9.6 × 10⁻⁴	23	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), ddCTP
HIV-1 RT (reverse transcriptase)	HIV-1	ddTTP	0.082	0.00856	9.58	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), ddTTP
HIV-1 RT (reverse transcriptase)	HIV-1	dGTP	0.0273	0.537	0.052	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), dGTP
HIV-1 RT (reverse transcriptase)	HIV-1	dTTPtemplate-primer D2-47/PG5-25 (47/25-mer DNA-DNA)	0.059	3.2 × 10⁻⁴	184.7	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), dTTP
HIV-1 RT (reverse transcriptase)	HIV-1	dTTPtemplate-primer D2-47/PG5-25C	0.0217	0.0413	0.53	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), dTTP
HIV-1 RT (reverse transcriptase)	HIV-1	dTTPtemplate-primer D2-47/PG5-25A	0.0025	0.266	0.0095	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), dTTP
HIV-1 RT (reverse transcriptase)	HIV-1	dTTPtemplate-primer D2-47/PG5-25G	0.0032	0.513	0.0062	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), dTTP
HIV-1 RT (reverse transcriptase)	HIV-1	rATP	0.0172	0.62	0.028	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase), rATP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	3'-azido-3'-deoxythymidine triphosphate	0.0187	0.0091	2.05	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, 3'-azido-3'-deoxythymidine triphosphate
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	dATP	0.0898	0.00485	18.5	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, dATP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	dCTPtemplate-primer D38G/25PGG (DNA-DNA); D38G/25PGG (DNA-DNA)	0.0408	0.00134	30.5	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, dCTP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	dCTPtemplate-primer D2-47/PG5-25 (47/25-mer DNA-DNA)	0.00128	3.359	3.8 × 10⁻⁴	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, dCTP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	ddATP	0.0267	0.129	0.2	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, ddATP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	ddCTP	0.0067	0.0265	0.248	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, ddCTP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	ddTTP	0.0188	0.385	0.048	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, ddTTP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	dGTP	0.003	0.91	0.0033	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, dGTP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	dTTPtemplate-primer D2-47/PG5-25 (47/25-mer DNA-DNA)	0.0233	0.00407	5.7	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, dTTP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	dTTPtemplate-primer D2-47/PG5-25C	0.013	0.858	0.0152	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, dTTP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	dTTPtemplate-primer D2-47/PG5-25A	5.3 × 10⁻⁴	0.824	6.5 × 10⁻⁴	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, dTTP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	dTTPtemplate-primer D2-47/PG5-25G	3.7 × 10⁻⁴	0.23	0.0016	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, dTTP
HIV-1 RT (reverse transcriptase)variant A114G	HIV-1	rATP	7.5 × 10⁻⁴	0.577	0.00132	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114G, rATP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	3'-azido-3'-deoxythymidine triphosphate	0.0865	0.0115	7.52	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, 3'-azido-3'-deoxythymidine triphosphate
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	dATP	0.1718	0.00122	140.8	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, dATP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	dCTPtemplate-primer D38G/25PGG (DNA-DNA); D38G/25PGG (DNA-DNA)	0.0917	5.75 × 10⁻⁴	159.3	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, dCTP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	dCTPtemplate-primer D2-47/PG5-25 (47/25-mer DNA-DNA)	0.0083	1.408	0.006	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, dCTP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	ddATP	0.037	0.00548	6.8	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, ddATP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	ddCTP	0.0132	7.97 × 10⁻⁴	16.5	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, ddCTP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	ddTTP	0.0138	0.00456	3.03	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, ddTTP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	dGTP	0.0028	0.121	0.023	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, dGTP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	dTTPtemplate-primer D2-47/PG5-25 (47/25-mer DNA-DNA)	0.0772	0.00202	38.2	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, dTTP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	dTTPtemplate-primer D2-47/PG5-25C	0.0273	0.28	0.098	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, dTTP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	dTTPtemplate-primer D2-47/PG5-25A	0.00163	0.319	0.0052	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, dTTP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	dTTPtemplate-primer D2-47/PG5-25G	0.00187	0.415	0.0045	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, dTTP
HIV-1 RT (reverse transcriptase)variant A114S	HIV-1	rATP	0.0077	0.83	0.0092	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114S, rATP
HIV-1 RT (reverse transcriptase)variant A114T	HIV-1	dTTP	0.088	—	—	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114T, dTTP
HIV-1 RT (reverse transcriptase)variant A114V	HIV-1	ddTTP	0.0342	0.412	0.083	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114V, ddTTP
HIV-1 RT (reverse transcriptase)variant A114V	HIV-1	dTTP	0.0788	0.071	1.12	pH 7, 37 °C	PMID 15548134	Open record: HIV-1 RT (reverse transcriptase) variant A114V, dTTP