Values CatLog read from this paper
Prostaglandin endoperoxide H synthases: peroxidase hydroperoxide specificity and cyclooxygenase activation
PMID 17462992doi:10.1074/jbc.m701235200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 44 records (115 values) from this paper: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity, prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1), prostaglandin endoperoxide H synthase-2 (huPGHS-2), peroxidase (POX) activity and 1 more from Ovis aries, Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 7 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity | Ovis aries | 15-hydroperoxyeicosatetraenoic acidsubstrate | 270 | 0.014 | 1.9 × 10⁴ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity | Ovis aries | 15-hydroperoxyeicosatetraenoic acidsubstrate (Fig. 2 hydroperoxide series) | — | — | 2.7 × 10³ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity | Ovis aries | ethyl hydroperoxide | — | — | 230 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity, ethyl hydroperoxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity | Ovis aries | hydrogen peroxidesubstrate | 150 | 2.9 | 54 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity | Ovis aries | hydrogen peroxidesubstrate (Fig. 2 hydroperoxide series) | — | — | 10 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity | Ovis aries | t-butyl hydroperoxide | — | — | 2.3 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity, t-butyl hydroperoxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant F409A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 670 | 0.098 | 6.8 × 10³ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant F409A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant F409A | Ovis aries | hydrogen peroxide | 180 | 8 | 23 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant F409A, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 730 | 0.022 | 3.3 × 10⁴ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294A | Ovis aries | hydrogen peroxide | 43 | 2.5 | 17 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294A, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294A/F409A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 480 | 0.066 | 7.3 × 10³ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294A/F409A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294A/F409A | Ovis aries | hydrogen peroxide | 410 | 7.4 | 55 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294A/F409A, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294A/L295A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 380 | 0.07 | 5.5 × 10³ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294A/L295A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294A/L295A | Ovis aries | hydrogen peroxide | 270 | 6.6 | 40 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294A/L295A, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294D | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 39 | 0.11 | 400 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294D, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294D | Ovis aries | hydrogen peroxide | 210 | 6.2 | 35 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294D, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294E | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 5.2 | 0.017 | 300 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294E, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294G | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 2 × 10³ | 0.14 | 1.5 × 10⁴ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294G, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294G | Ovis aries | hydrogen peroxide | 1.4 × 10³ | 14 | 97 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294G, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294S | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 2.1 × 10³ | 0.21 | 1 × 10⁴ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294S, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L294S | Ovis aries | hydrogen peroxide | 1.2 × 10³ | 17 | 72 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L294S, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L295A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 230 | 0.46 | 500 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L295A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L295A | Ovis aries | hydrogen peroxide | 160 | 6.4 | 25 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L295A, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L295A/L408A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 72 | 0.033 | 2.2 × 10³ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L295A/L408A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L295A/L408A | Ovis aries | hydrogen peroxide | 93 | 4.6 | 20 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L295A/L408A, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L408A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 35 | 0.02 | 1.7 × 10³ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L408A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant L408A | Ovis aries | hydrogen peroxide | 30 | 4.8 | 6.7 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant L408A, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant Q203N | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 53 | 0.08 | 700 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant Q203N, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant Q203N | Ovis aries | hydrogen peroxide | 11 | 8.4 | 1.3 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant Q203N, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant Q203V | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 135 | 0.042 | 3.2 × 10³ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant Q203V, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant Q203V | Ovis aries | hydrogen peroxide | 37 | 17 | 2.3 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant Q203V, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant V291A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 300 | 0.031 | 9.8 × 10³ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant V291A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant V291A | Ovis aries | hydrogen peroxide | 230 | 7.3 | 32 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant V291A, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant V291A/L294A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 300 | 0.028 | 1.1 × 10⁴ calc. | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant V291A/L294A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant V291A/L294A | Ovis aries | hydrogen peroxide | 540 | 11 | 49 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant V291A/L294A, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant V291A/L294A/L295A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 290 | 0.12 | 2.5 × 10³ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant V291A/L294A/L295A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activityvariant V291A/L294A/L295A | Ovis aries | hydrogen peroxide | 610 | 8.9 | 68 | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (ovPGHS-1), peroxidase (POX) activity variant V291A/L294A/L295A, hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1) | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | 120 | 0.042 | 2.9 × 10³ calc. | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1), 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1) | Ovis aries | ethyl hydroperoxide | 130 | 0.58 | 220 calc. | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1), ethyl hydroperoxide |
| prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1) | Ovis aries | hydrogen peroxide | 17 | 1.7 | 10 calc. | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1), hydrogen peroxide |
| prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1) | Ovis aries | t-butyl hydroperoxide | 35 | 15 | 2.3 calc. | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1), t-butyl hydroperoxide |
| prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1)variant V291A/L294A | Ovis aries | 15-hydroperoxyeicosatetraenoic acid | — | — | 1.1 × 10⁴ | pH 8 | Open record: prostaglandin endoperoxide H synthase-1 (PGHS-1, COX-1) variant V291A/L294A, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-2 (huPGHS-2), peroxidase (POX) activity | Homo sapiens | 15-hydroperoxyeicosatetraenoic acid | 253 | 0.088 | 2.9 × 10³ calc. | pH 8, 4 °C | Open record: prostaglandin endoperoxide H synthase-2 (huPGHS-2), peroxidase (POX) activity, 15-hydroperoxyeicosatetraenoic acid |
| prostaglandin endoperoxide H synthase-2 (PGHS-2, COX-2) | Homo sapiens | 15-hydroperoxyeicosatetraenoic acid | 253 | 0.088 | 2.9 × 10³ calc. | pH 8, 4 °C | Open record: prostaglandin endoperoxide H synthase-2 (PGHS-2, COX-2), 15-hydroperoxyeicosatetraenoic acid |