Values CatLog read from this paper

Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors

PMID 8218285doi:10.1021/bi00096a018Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 16 records (48 values) from this paper: acetylcholinesterase from Mus musculus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.1.1.7

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
acetylcholinesterasevariant D74N	Mus musculus	acetylthiocholine	1.4 × 10³	1.3	1.05 × 10³	pH 7, 22 °C	Open record: acetylcholinesterase variant D74N, acetylthiocholine
acetylcholinesterasevariant F295Y	Mus musculus	acetylthiocholine	102	0.017	6 × 10³	pH 7, 22 °C	Open record: acetylcholinesterase variant F295Y, acetylthiocholine
acetylcholinesterasevariant F297Y	Mus musculus	acetylthiocholine	650	0.058	1.12 × 10⁴	pH 7, 22 °C	Open record: acetylcholinesterase variant F297Y, acetylthiocholine
acetylcholinesterasevariant F338G	Mus musculus	acetylthiocholine	380	0.075	5.2 × 10³	pH 7, 22 °C	Open record: acetylcholinesterase variant F338G, acetylthiocholine
acetylcholinesterasevariant W286R	Mus musculus	acetylthiocholine	2.7 × 10³	0.42	6.3 × 10³	pH 7, 22 °C	Open record: acetylcholinesterase variant W286R, acetylthiocholine
acetylcholinesterasevariant Y124Q	Mus musculus	acetylthiocholine	1.8 × 10³	0.12	1.57 × 10⁴	pH 7, 22 °C	Open record: acetylcholinesterase variant Y124Q, acetylthiocholine
acetylcholinesterasevariant Y124Q/W286R	Mus musculus	acetylthiocholine	2.7 × 10³	0.7	3.8 × 10³	pH 7, 22 °C	Open record: acetylcholinesterase variant Y124Q/W286R, acetylthiocholine
acetylcholinesterasevariant Y337A	Mus musculus	acetylthiocholine	870	0.11	7.7 × 10³	pH 7, 22 °C	Open record: acetylcholinesterase variant Y337A, acetylthiocholine
acetylcholinesterasevariant Y337F	Mus musculus	acetylthiocholine	1.13 × 10³	0.053	2.2 × 10⁴	pH 7, 22 °C	Open record: acetylcholinesterase variant Y337F, acetylthiocholine
acetylcholinesterasevariant Y72N	Mus musculus	acetylthiocholine	2.2 × 10³	0.11	2 × 10⁴	pH 7, 22 °C	Open record: acetylcholinesterase variant Y72N, acetylthiocholine
acetylcholinesterasevariant Y72N/D74N/Y124Q/W286A	Mus musculus	acetylthiocholine	2.5 × 10³	2.1	1.18 × 10³	pH 7, 22 °C	Open record: acetylcholinesterase variant Y72N/D74N/Y124Q/W286A, acetylthiocholine
acetylcholinesterasevariant Y72N/D74N/Y124Q/W286R	Mus musculus	acetylthiocholine	2.3 × 10³	6.1	380	pH 7, 22 °C	Open record: acetylcholinesterase variant Y72N/D74N/Y124Q/W286R, acetylthiocholine
acetylcholinesterasevariant Y72N/W286R	Mus musculus	acetylthiocholine	3.2 × 10³	0.67	4.7 × 10³	pH 7, 22 °C	Open record: acetylcholinesterase variant Y72N/W286R, acetylthiocholine
acetylcholinesterasevariant Y72N/Y124Q	Mus musculus	acetylthiocholine	1.57 × 10³	0.095	1.65 × 10⁴	pH 7, 22 °C	Open record: acetylcholinesterase variant Y72N/Y124Q, acetylthiocholine
acetylcholinesterasevariant Y72N/Y124Q/W286A	Mus musculus	acetylthiocholine	2.5 × 10³	0.23	1.12 × 10⁴	pH 7, 22 °C	Open record: acetylcholinesterase variant Y72N/Y124Q/W286A, acetylthiocholine
acetylcholinesterasevariant Y72N/Y124Q/W286R	Mus musculus	acetylthiocholine	3.5 × 10³	0.85	4.2 × 10³	pH 7, 22 °C	Open record: acetylcholinesterase variant Y72N/Y124Q/W286R, acetylthiocholine