Values CatLog read from this paper
Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues
PMID 24733394doi:10.1074/jbc.m114.555573Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (18 values) from this paper: MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase) from Rattus norvegicus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 1.5.1.5, EC 1.5.1.15, EC 3.5.4.9
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase) | Rattus norvegicus | 5,10-methylenetetrahydropteroylmonoglutamate (5,10-methylenetetrahydrofolate)5 mM MgCl2; 25 mM potassium phosphate | 2.7 | 0.04 | 67 | pH 8, 30 °C | Open record: MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase), 5,10-methylenetetrahydropteroylmonoglutamate (5,10-methylenetetrahydrofolate) |
| MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase) | Rattus norvegicus | 5,10-methylenetetrahydropteroylmonoglutamate (5,10-methylenetetrahydrofolate)5 mM MgCl2 (Methods reaction buffer); no phosphate | 1.3 | 0.042 | 30 | pH 8, 30 °C | Open record: MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase), 5,10-methylenetetrahydropteroylmonoglutamate (5,10-methylenetetrahydrofolate) |
| MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase) | Rattus norvegicus | 5,10-methylenetetrahydropteroylpentaglutamate5 mM MgCl2; 25 mM potassium phosphate | 8.8 | 0.13 | 68 | pH 8, 30 °C | Open record: MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase), 5,10-methylenetetrahydropteroylpentaglutamate |
| MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase) | Rattus norvegicus | 5,10-methylenetetrahydropteroylpentaglutamate5 mM MgCl2 (Methods reaction buffer); no phosphate | 7.2 | 0.153 | 47 | pH 8, 30 °C | Open record: MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase), 5,10-methylenetetrahydropteroylpentaglutamate |
| MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase) | Rattus norvegicus | NAD+ | 3.6 | 0.147 | 25 | pH 8, 30 °C | Open record: MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase), NAD+ |
| MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase) | Rattus norvegicus | NADP+ | 1.1 | 0.537 | 2 | pH 8, 30 °C | Open record: MTHFD2L (mitochondrial bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase), NADP+ |