CatLogenzyme kinetics catalog

Values CatLog read from this paper

Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs

PMID 24992307doi:10.1371/journal.ppat.1004245Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 16 records (46 values) from this paper: trehalose-6-phosphate phosphatase (T6PP) from Brugia malayi.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.1.3.12

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
trehalose-6-phosphate phosphatase (T6PP)Brugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate240.3669pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant D215ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate4 × 10⁻⁴——pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant D336ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate0.0940.0460.2pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant D378ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate110.2739pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant E384ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate30.130pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant E386ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate20.08228pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant K334ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate0.060.50.11pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant N228ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate180.04450pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant Q332ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate0.220.20.55pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant R337ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate0.280.41.5pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant S329ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate40.2515pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant T339ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate150.277pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant W280ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate190.15120pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant Y221ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate10.333pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant Y225ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate60.1536pH 7.5Open
trehalose-6-phosphate phosphatase (T6PP)variant Δ59Brugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate280.26110pH 7.5Open