CatLogenzyme kinetics catalog

EC 3.1.3.12: trehalose-phosphatase

HydrolasesOpen in Browse

CatLog read 22 records for EC 3.1.3.12 from 3 papers, for 3 organisms. Names in these papers: trehalose-6-phosphate phosphatase (T6PP), trehalose-6-phosphate phosphatase (TPP), OtsB (HAD17).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 31 records for EC 3.1.3.12 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.3.12 in Browse.

Papers

PaperOrganismsRecords
Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugsBrugia malayi16
Cloning, expression and characterization of trehalose-6-phosphate phosphatase from a psychrotrophic bacterium, Arthrobacter strain A3Arthrobacter sp.5
Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase familyEscherichia coli1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
OtsB (HAD17)Escherichia colitrehalose 6-phosphate9.10.6115PMID 16990279Open
trehalose-6-phosphate phosphatase (T6PP)Brugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate240.3669pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant D215ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate4 × 10⁻⁴——pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant D336ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate0.0940.0460.2pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant D378ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate110.2739pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant E384ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate30.130pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant E386ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate20.08228pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant K334ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate0.060.50.11pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant N228ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate180.04450pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant Q332ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate0.220.20.55pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant R337ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate0.280.41.5pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant S329ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate40.2515pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant T339ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate150.277pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant W280ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate190.15120pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant Y221ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate10.333pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant Y225ABrugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate60.1536pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (T6PP)variant Δ59Brugia malayialpha-D-glucopyranosyl-(1->1)-alpha-D-glucopyranoside 6-phosphate280.26110pH 7.5PMID 24992307Open
trehalose-6-phosphate phosphatase (TPP)Arthrobacter sp.trehalose 6-phosphate1.490.463.2pH 7.5, 4 °CPMID 22806197Open
trehalose-6-phosphate phosphatase (TPP)Arthrobacter sp.trehalose 6-phosphate3.940.2814.3pH 7.5, 10 °CPMID 22806197Open
trehalose-6-phosphate phosphatase (TPP)Arthrobacter sp.trehalose 6-phosphate3.90.1428pH 7.5, 20 °CPMID 22806197Open
trehalose-6-phosphate phosphatase (TPP)Arthrobacter sp.trehalose 6-phosphate14.790.3937.5pH 7.5, 30 °CPMID 22806197Open
trehalose-6-phosphate phosphatase (TPP)Arthrobacter sp.trehalose 6-phosphate12.650.5124.6pH 7.5, 37 °CPMID 22806197Open