Values CatLog read from this paper
Probing the acyl-binding pocket of aminoacylase-1
PMID 18341290doi:10.1021/bi702156hOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 43 records (121 values) from this paper: aminoacylase-1 from Homo sapiens, Sus scrofa.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| aminoacylase-1 | Homo sapiens | N-(2,2-dimethylpropanoyl)-L-methionine | 0.0015 | 168 | 8.9 × 10⁻⁶ | pH 7.4 | Open record: aminoacylase-1, N-(2,2-dimethylpropanoyl)-L-methionine |
| aminoacylase-1 | Homo sapiens | N-(2-methylpropanoyl)-L-methionine | 0.529 | 15.3 | 0.035 | pH 7.4 | Open record: aminoacylase-1, N-(2-methylpropanoyl)-L-methionine |
| aminoacylase-1 | Homo sapiens | N-(3-methylbutanoyl)-L-methionine | 0.105 | 4.27 | 0.025 | pH 7.4 | Open record: aminoacylase-1, N-(3-methylbutanoyl)-L-methionine |
| aminoacylase-1 | Homo sapiens | N-(cyclohexanecarbonyl)-L-methionine | 0.00623 | 6.23 | 0.001 | pH 7.4 | Open record: aminoacylase-1, N-(cyclohexanecarbonyl)-L-methionine |
| aminoacylase-1 | Homo sapiens | N-(cyclopentanecarbonyl)-L-methionine | 13.3 | 7.18 | 1.85 | pH 7.4 | Open record: aminoacylase-1, N-(cyclopentanecarbonyl)-L-methionine |
| aminoacylase-1 | Homo sapiens | N-benzoyl-L-glutamic acid | 0.0101 | 1.63 | 0.0062 | pH 7.4 | Open record: aminoacylase-1, N-benzoyl-L-glutamic acid |
| aminoacylase-1 | Homo sapiens | N-benzoyl-L-methionine | 0.158 | 0.81 | 0.198 | pH 7.4 | Open record: aminoacylase-1, N-benzoyl-L-methionine |
| aminoacylase-1 | Homo sapiens | N-butanoyl-L-methionine | 139 | 0.73 | 101.5 | pH 7.4 | Open record: aminoacylase-1, N-butanoyl-L-methionine |
| aminoacylase-1 | Homo sapiens | N-formyl-L-methionine | 177 | 16.8 | 10.5 | pH 7.4 | Open record: aminoacylase-1, N-formyl-L-methionine |
| aminoacylase-1 | Homo sapiens | N-hexanoyl-L-methionine | 16.1 | 1.01 | 15.9 | pH 7.4 | Open record: aminoacylase-1, N-hexanoyl-L-methionine |
| aminoacylase-1 | Homo sapiens | N-pentanoyl-L-methionine | 16.2 | 0.19 | 85.3 | pH 7.4 | Open record: aminoacylase-1, N-pentanoyl-L-methionine |
| aminoacylase-1 | Homo sapiens | N-propanoyl-L-methionine | 25.7 | 0.34 | 75.6 | pH 7.4 | Open record: aminoacylase-1, N-propanoyl-L-methionine |
| aminoacylase-1variant I177A | Homo sapiens | N-acetyl-L-methionine | 66.7 | 1.14 | 58.5 | pH 7.4 | Open record: aminoacylase-1 variant I177A, N-acetyl-L-methionine |
| aminoacylase-1variant I177A | Homo sapiens | N-hexanoyl-L-methionine | 9.51 | 3.56 | 2.67 | pH 7.4 | Open record: aminoacylase-1 variant I177A, N-hexanoyl-L-methionine |
| aminoacylase-1variant I177L | Homo sapiens | N-acetyl-L-methionine | 93.7 | 1.72 | 54.5 | pH 7.4 | Open record: aminoacylase-1 variant I177L, N-acetyl-L-methionine |
| aminoacylase-1variant I177L | Homo sapiens | N-hexanoyl-L-methionine | 39.4 | 5.22 | 7.55 | pH 7.4 | Open record: aminoacylase-1 variant I177L, N-hexanoyl-L-methionine |
| aminoacylase-1variant L372A | Homo sapiens | N-(3-methylbutanoyl)-L-methionine | 5.36 | 2.1 | 2.55 | pH 7.4 | Open record: aminoacylase-1 variant L372A, N-(3-methylbutanoyl)-L-methionine |
| aminoacylase-1variant L372A | Homo sapiens | N-acetyl-L-methionine | — | — | 2.36 | pH 7.4 | Open record: aminoacylase-1 variant L372A, N-acetyl-L-methionine |
| aminoacylase-1variant L372G | Homo sapiens | N-(3-methylbutanoyl)-L-methionine | — | — | 0.137 | pH 7.4 | Open record: aminoacylase-1 variant L372G, N-(3-methylbutanoyl)-L-methionine |
| aminoacylase-1variant L372G | Homo sapiens | N-acetyl-L-methionine | 16.6 | 4.32 | 3.84 | pH 7.4 | Open record: aminoacylase-1 variant L372G, N-acetyl-L-methionine |
| aminoacylase-1variant L372I | Homo sapiens | N-(3-methylbutanoyl)-L-methionine | 2.01 | 7.29 | 0.276 | pH 7.4 | Open record: aminoacylase-1 variant L372I, N-(3-methylbutanoyl)-L-methionine |
| aminoacylase-1variant L372I | Homo sapiens | N-acetyl-L-methionine | 4.49 | 1.35 | 3.33 | pH 7.4 | Open record: aminoacylase-1 variant L372I, N-acetyl-L-methionine |
| aminoacylase-1variant L372V | Homo sapiens | N-(3-methylbutanoyl)-L-methionine | 0.34 | 0.54 | 0.63 | pH 7.4 | Open record: aminoacylase-1 variant L372V, N-(3-methylbutanoyl)-L-methionine |
| aminoacylase-1variant L372V | Homo sapiens | N-acetyl-L-methionine | 12.1 | 2.76 | 4.38 | pH 7.4 | Open record: aminoacylase-1 variant L372V, N-acetyl-L-methionine |
| aminoacylase-1variant T347F | Homo sapiens | N-acetyl-L-methionine | 1.2 | 0.76 | 1.58 | pH 7.4 | Open record: aminoacylase-1 variant T347F, N-acetyl-L-methionine |
| aminoacylase-1variant T347G | Homo sapiens | N-(cyclohexanecarbonyl)-L-methionine | — | — | 0.00401 | pH 7.4 | Open record: aminoacylase-1 variant T347G, N-(cyclohexanecarbonyl)-L-methionine |
| aminoacylase-1variant T347S | Homo sapiens | N-(cyclohexanecarbonyl)-L-methionine | 0.129 | 1.17 | 0.11 | pH 7.4 | Open record: aminoacylase-1 variant T347S, N-(cyclohexanecarbonyl)-L-methionine |
| aminoacylase-1variant T347S | Homo sapiens | N-acetyl-L-glutamic acid | 63.4 | 70 | 0.906 | pH 7.4 | Open record: aminoacylase-1 variant T347S, N-acetyl-L-glutamic acid |
| aminoacylase-1variant T347S | Homo sapiens | N-acetyl-L-methionine | 64.6 | 0.4 | 162 | pH 7.4 | Open record: aminoacylase-1 variant T347S, N-acetyl-L-methionine |
| aminoacylase-1variant T347S | Homo sapiens | N-benzoyl-L-glutamic acid | — | — | 1.02 | pH 7.4 | Open record: aminoacylase-1 variant T347S, N-benzoyl-L-glutamic acid |
| aminoacylase-1variant T347S | Homo sapiens | N-benzoyl-L-methionine | 20.1 | 0.41 | 49 | pH 7.4 | Open record: aminoacylase-1 variant T347S, N-benzoyl-L-methionine |
| aminoacylase-1 | Sus scrofa | N-(2,2-dimethylpropanoyl)-L-methionine | 0.0015 | 585 | 2.5 × 10⁻⁶ | pH 7.4 | Open record: aminoacylase-1, N-(2,2-dimethylpropanoyl)-L-methionine |
| aminoacylase-1 | Sus scrofa | N-(2-methylpropanoyl)-L-methionine | 89.8 | 58.5 | 1.54 | pH 7.4 | Open record: aminoacylase-1, N-(2-methylpropanoyl)-L-methionine |
| aminoacylase-1 | Sus scrofa | N-(3-methylbutanoyl)-L-methionine | 0.694 | 0.9 | 0.771 | pH 7.4 | Open record: aminoacylase-1, N-(3-methylbutanoyl)-L-methionine |
| aminoacylase-1 | Sus scrofa | N-(cyclohexanecarbonyl)-L-methionine | 0.145 | 0.31 | 0.468 | pH 7.4 | Open record: aminoacylase-1, N-(cyclohexanecarbonyl)-L-methionine |
| aminoacylase-1 | Sus scrofa | N-(cyclopentanecarbonyl)-L-methionine | 11.2 | 0.64 | 17.5 | pH 7.4 | Open record: aminoacylase-1, N-(cyclopentanecarbonyl)-L-methionine |
| aminoacylase-1 | Sus scrofa | N-benzoyl-L-glutamic acid | 0.115 | 3.71 | 0.031 | pH 7.4 | Open record: aminoacylase-1, N-benzoyl-L-glutamic acid |
| aminoacylase-1 | Sus scrofa | N-benzoyl-L-methionine | 1.3 | 0.38 | 3.42 | pH 7.4 | Open record: aminoacylase-1, N-benzoyl-L-methionine |
| aminoacylase-1 | Sus scrofa | N-butanoyl-L-methionine | 107 | 0.31 | 345 | pH 7.4 | Open record: aminoacylase-1, N-butanoyl-L-methionine |
| aminoacylase-1 | Sus scrofa | N-formyl-L-methionine | 200 | 35.4 | 5.65 | pH 7.4 | Open record: aminoacylase-1, N-formyl-L-methionine |
| aminoacylase-1 | Sus scrofa | N-hexanoyl-L-methionine | 4.3 | 0.01 | 430 | pH 7.4 | Open record: aminoacylase-1, N-hexanoyl-L-methionine |
| aminoacylase-1 | Sus scrofa | N-pentanoyl-L-methionine | 18.2 | 0.03 | 607 | pH 7.4 | Open record: aminoacylase-1, N-pentanoyl-L-methionine |
| aminoacylase-1 | Sus scrofa | N-propanoyl-L-methionine | 168 | 0.55 | 3055 | pH 7.4 | Open record: aminoacylase-1, N-propanoyl-L-methionine |