CatLogenzyme kinetics catalog

Values CatLog read from this paper

Engineering the substrate specificity of the Abl tyrosine kinase

PMID 9988744doi:10.1074/jbc.274.8.4995Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 35 records (35 values) from this paper: v-Abl tyrosine kinase (catalytic domain, Abl-CAT) from Abelson murine leukemia virus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.7.10.2

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)Abelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly—1.4—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)Abelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-His-Tyr-Ala-Ala-Arg-Gly—0.6—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)Abelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Ile-Tyr-Ala-Ala-Arg-Gly—0.4—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)Abelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Leu-Tyr-Ala-Ala-Arg-Gly—0.8—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)Abelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Ala-Thr-Met-Gln-Ile-Gly—0.4—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)Abelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Ile-Thr-Met-Gln-Ile-Gly—0.5—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)Abelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Met-Thr-Pro-Gln-Ile-Gly—0.7—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)Abelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Met-Thr-Thr-Gln-Ile-Gly—1.8—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)Abelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Nle-Thr-Met-Gln-Ile-Gly (Nle = norleucine)—0.5—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant F521AAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Ala-Thr-Met-Gln-Ile-Gly—0.4—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant F521AAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Ile-Thr-Met-Gln-Ile-Gly—1.5—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant F521AAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Nle-Thr-Met-Gln-Ile-Gly (Nle = norleucine)—0.4—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant G556VAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Ile-Tyr-Ala-Ala-Arg-Gly—0.6—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant G556VAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Leu-Tyr-Ala-Ala-Arg-Gly—0.7—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant I523VAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Ala-Thr-Met-Gln-Ile-Gly—0.5—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant I523VAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Ile-Thr-Met-Gln-Ile-Gly—0.5—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant I523VAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Nle-Thr-Met-Gln-Ile-Gly (Nle = norleucine)—0.5—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant L444EAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-His-Tyr-Ala-Ala-Arg-Gly—0.4—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant L444EAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Ile-Tyr-Ala-Ala-Arg-Gly—0.7—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant L444KAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-His-Tyr-Ala-Ala-Arg-Gly—1.3—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant L444KAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Ile-Tyr-Ala-Ala-Arg-Gly—0.9—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant S558NAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-His-Tyr-Ala-Ala-Arg-Gly—0.2—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant S558NAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Ile-Tyr-Ala-Ala-Arg-Gly—0.3—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant W525FAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly—1.3—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant W525FAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-His-Tyr-Ala-Ala-Arg-Gly—0.5—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant W525FAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Ile-Tyr-Ala-Ala-Arg-Gly—0.6—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant W525HAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly—0.7—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant W525HAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-His-Tyr-Ala-Ala-Arg-Gly—1.5—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant W525HAbelson murine leukemia virusLys-Lys-Leu-Ile-Glu-Asp-Ala-Ile-Tyr-Ala-Ala-Arg-Gly—0.4—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant Y569LAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Ala-Thr-Met-Gln-Ile-Gly—0.8—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant Y569LAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Met-Thr-Pro-Gln-Ile-Gly—1—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant Y569LAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Met-Thr-Thr-Gln-Ile-Gly—0.9—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant Y569LAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Nle-Thr-Met-Gln-Ile-Gly (Nle = norleucine)—0.5—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant Y569WAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Ala-Thr-Met-Gln-Ile-Gly—0.5—Open
v-Abl tyrosine kinase (catalytic domain, Abl-CAT)variant Y569WAbelson murine leukemia virusLys-Lys-Ser-Arg-Gly-Asp-Tyr-Met-Thr-Pro-Gln-Ile-Gly—1.9—Open