CatLogenzyme kinetics catalog

Values CatLog read from this paper

The comparative interaction of quinonoid (6R)-dihydrobiopterin and an alternative dihydropterin substrate with wild-type and mutant rat dihydropteridine reductases

PMID 9235988doi:10.1021/bi970585iOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 24 records (58 values) from this paper: dihydropteridine reductase (DHPR) from Rattus norvegicus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.6.99.7

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
dihydropteridine reductase (DHPR)Rattus norvegicusNADH—0.0054.6 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)Rattus norvegicusquinonoid (6R)-L-erythro-dihydrobiopterin234 × 10⁻⁴5.75 × 10⁴pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant A133SRattus norvegicusNADHcosubstrate q-6,7-diMePtH2—0.0226.9 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant A133SRattus norvegicusNADHcosubstrate qBH2—0.0045 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant A133SRattus norvegicusquinonoid (6R)-L-erythro-dihydrobiopterin204 × 10⁻⁴5 × 10⁴pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant A133SRattus norvegicusquinonoid 6,7-dimethyldihydropteridine1520.0081.9 × 10⁴pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant K150QRattus norvegicusNADHcosubstrate q-6,7-diMePtH2—0.0134 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant K150QRattus norvegicusNADHcosubstrate qBH2—0.0793.4 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant K150QRattus norvegicusquinonoid (6R)-L-erythro-dihydrobiopterin2690.0289.6 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant K150QRattus norvegicusquinonoid 6,7-dimethyldihydropteridine520.29200pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146FRattus norvegicusNADHcosubstrate q-6,7-diMePtH2—0.0035.7 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146FRattus norvegicusNADHcosubstrate qBH2—0.0512.7 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146FRattus norvegicusquinonoid (6R)-L-erythro-dihydrobiopterin1380.308500pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146FRattus norvegicusquinonoid 6,7-dimethyldihydropteridine170.4640pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146F/A133SRattus norvegicusNADHcosubstrate q-6,7-diMePtH2—0.0021 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146F/A133SRattus norvegicusNADHcosubstrate qBH2—0.0089.3 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146F/A133SRattus norvegicusquinonoid (6R)-L-erythro-dihydrobiopterin740.0243.1 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146F/A133SRattus norvegicusquinonoid 6,7-dimethyldihydropteridine20.120pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146F/K150QRattus norvegicusNADH—0.021 × 10⁴pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146F/K150QRattus norvegicusquinonoid (6R)-L-erythro-dihydrobiopterin200——pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146HRattus norvegicusNADHcosubstrate q-6,7-diMePtH2—0.0084.5 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146HRattus norvegicusNADHcosubstrate qBH2—0.0245.8 × 10³pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146HRattus norvegicusquinonoid (6R)-L-erythro-dihydrobiopterin1390.0071.99 × 10⁴pH 6.8, 25 °COpen
dihydropteridine reductase (DHPR)variant Y146HRattus norvegicusquinonoid 6,7-dimethyldihydropteridine360.17200pH 6.8, 25 °COpen