Values CatLog read from this paper

The kinetics of pig heart triphosphopyridine nucleotide-isocitrate dehydrogenase. I. Initial velocity, substrate and product inhibition, and isotope exchange studies

PMID 4151308doi:10.1016/s0021-9258(19)42719-1Open in Browse

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CatLog read 18 records (18 values) from this paper: TPN-isocitrate dehydrogenase from Sus scrofa.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.42

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
TPN-isocitrate dehydrogenase	Sus scrofa	2-oxoglutaratecosubstrate TPNH and CO2; average of the supernatant	—	0.038	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, 2-oxoglutarate
TPN-isocitrate dehydrogenase	Sus scrofa	2-oxoglutarateCO2 and α-ketoglutarate varied at fixed 10 µM TPNH; Table I	—	0.025	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, 2-oxoglutarate
TPN-isocitrate dehydrogenase	Sus scrofa	2-oxoglutaratecosubstrate CO2 9.5 mM; TPNH varied; Table I	—	0.054	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, 2-oxoglutarate
TPN-isocitrate dehydrogenase	Sus scrofa	2-oxoglutaratecosubstrate CO2 9.5 mM; TPNH varied; Table I	—	0.056	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, 2-oxoglutarate
TPN-isocitrate dehydrogenase	Sus scrofa	carbon dioxideTPNH and α-ketoglutarate; in the text	—	2.2	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, carbon dioxide
TPN-isocitrate dehydrogenase	Sus scrofa	carbon dioxideCO2 and α-ketoglutarate varied at fixed 10 µM TPNH; Table I	—	2.7	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, carbon dioxide
TPN-isocitrate dehydrogenase	Sus scrofa	carbon dioxideα-ketoglutarate fixed; TPNH varied; Table I	—	2.1	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, carbon dioxide
TPN-isocitrate dehydrogenase	Sus scrofa	carbon dioxideCO2 and α-ketoglutarate varied at fixed 10 µM TPNH; Table I	—	1.9	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, carbon dioxide
TPN-isocitrate dehydrogenase	Sus scrofa	reduced triphosphopyridine nucleotide (NADPH)α-ketoglutarate and CO2; average of the supernatant	—	0.0014	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, reduced triphosphopyridine nucleotide (NADPH)
TPN-isocitrate dehydrogenase	Sus scrofa	reduced triphosphopyridine nucleotide (NADPH)α-ketoglutarate fixed; CO2 varied; Table I	—	0.0014	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, reduced triphosphopyridine nucleotide (NADPH)
TPN-isocitrate dehydrogenase	Sus scrofa	reduced triphosphopyridine nucleotide (NADPH)CO2 9.5 mM; α-ketoglutarate varied; Table I	—	0.0023	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, reduced triphosphopyridine nucleotide (NADPH)
TPN-isocitrate dehydrogenase	Sus scrofa	reduced triphosphopyridine nucleotide (NADPH)CO2 9.5 mM; α-ketoglutarate varied; Table I	—	0.0033	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, reduced triphosphopyridine nucleotide (NADPH)
TPN-isocitrate dehydrogenase	Sus scrofa	threo-Ds-isocitratecosubstrate TPN; average of the supernatant; in the text	—	0.0011	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, threo-Ds-isocitrate
TPN-isocitrate dehydrogenase	Sus scrofa	threo-Ds-isocitratecosubstrate TPN (varied); Table I	—	5.6 × 10⁻⁴	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, threo-Ds-isocitrate
TPN-isocitrate dehydrogenase	Sus scrofa	threo-Ds-isocitratecosubstrate TPN (varied); Table I	—	0.0012	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, threo-Ds-isocitrate
TPN-isocitrate dehydrogenase	Sus scrofa	threo-Ds-isocitratecosubstrate TPN (varied); Table I	—	0.0015	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, threo-Ds-isocitrate
TPN-isocitrate dehydrogenase	Sus scrofa	triphosphopyridine nucleotide (NADP+)cosubstrate threo-Ds-isocitrate; average of the supernatant	—	2.5 × 10⁻⁴	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, triphosphopyridine nucleotide (NADP+)
TPN-isocitrate dehydrogenase	Sus scrofa	triphosphopyridine nucleotide (NADP+)cosubstrate threo-Ds-isocitrate (varied)	—	1.9 × 10⁻⁴	—	pH 6.8, 25 °C	Open record: TPN-isocitrate dehydrogenase, triphosphopyridine nucleotide (NADP+)