Values CatLog read from this paper
A simple two step procedure for purification of the catalytic domain of chicken tryptophan hydroxylase 1 in a form suitable for crystallization
PMID 18055219doi:10.1016/j.pep.2007.10.016Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 4 records (8 values) from this paper: tryptophan hydroxylase 1 catalytic domain (cTPH1) from Gallus gallus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 4 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| tryptophan hydroxylase 1 catalytic domain (cTPH1) | Gallus gallus | (6R)-5,6,7,8-tetrahydro-L-biopterinL-tryptophan 70 uM; O2 500 uM | 0.72 | 0.324 | 2.2 calc. | pH 7, 15 °C | Open record: tryptophan hydroxylase 1 catalytic domain (cTPH1), (6R)-5,6,7,8-tetrahydro-L-biopterin |
| tryptophan hydroxylase 1 catalytic domain (cTPH1) | Gallus gallus | (6R)-5,6,7,8-tetrahydro-L-biopterinL-tryptophan 10 uM; O2 133 uM | 0.327 | 0.071 | 4.6 calc. | pH 7, 15 °C | Open record: tryptophan hydroxylase 1 catalytic domain (cTPH1), (6R)-5,6,7,8-tetrahydro-L-biopterin |
| tryptophan hydroxylase 1 catalytic domain (cTPH1) | Gallus gallus | dioxygen | 0.38 | 0.039 | 9.7 calc. | pH 7, 15 °C | Open record: tryptophan hydroxylase 1 catalytic domain (cTPH1), dioxygen |
| tryptophan hydroxylase 1 catalytic domain (cTPH1) | Gallus gallus | L-tryptophan | 0.53 | 0.0077 | 69 calc. | pH 7, 15 °C | Open record: tryptophan hydroxylase 1 catalytic domain (cTPH1), L-tryptophan |