Values CatLog read from this paper
Biochemical and genetic analysis of methylenetetrahydrofolate reductase in Leishmania metabolism and virulence
PMID 17032644doi:10.1074/jbc.m608387200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 5 records (15 values) from this paper: methylenetetrahydrofolate reductase (LmjMTHFR) from Leishmania major.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| methylenetetrahydrofolate reductase (LmjMTHFR) | Leishmania major | (6R)-5,10-methylenetetrahydrofolate | 11.1 | 0.015 | 740 | pH 7.2, 37 °C | Open record: methylenetetrahydrofolate reductase (LmjMTHFR), (6R)-5,10-methylenetetrahydrofolate |
| methylenetetrahydrofolate reductase (LmjMTHFR) | Leishmania major | NADH50 mM sodium phosphate pH 7.2 | 52 | 0.053 | 980 | pH 7.2, 37 °C | Open record: methylenetetrahydrofolate reductase (LmjMTHFR), NADH |
| methylenetetrahydrofolate reductase (LmjMTHFR) | Leishmania major | NADH50 mM Tris-Cl pH 7.2 | 87 | 0.09 | 970 | pH 7.2, 37 °C | Open record: methylenetetrahydrofolate reductase (LmjMTHFR), NADH |
| methylenetetrahydrofolate reductase (LmjMTHFR) | Leishmania major | NADPH50 mM sodium phosphate pH 7.2 | 74 | 0.09 | 820 | pH 7.2, 37 °C | Open record: methylenetetrahydrofolate reductase (LmjMTHFR), NADPH |
| methylenetetrahydrofolate reductase (LmjMTHFR) | Leishmania major | NADPH50 mM Tris-Cl pH 7.2 | 140 | 0.17 | 820 | pH 7.2, 37 °C | Open record: methylenetetrahydrofolate reductase (LmjMTHFR), NADPH |