CatLogenzyme kinetics catalog

Values CatLog read from this paper

The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity

PMID 31578392doi:10.1038/s41598-019-50673-4Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 30 records (45 values) from this paper: pyridoxal kinase (PDXK) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 15 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 2.7.1.35

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
pyridoxal kinase (PDXK)Homo sapiensadenosine 5'-triphosphatePLP formation followed directly at 388 nm (1 µM enzyme)—0.407—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)Homo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PN—0.104—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)Homo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PM—0.0462—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)Homo sapienspyridoxal0.970.1895.1 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)Homo sapienspyridoxamine0.1150.00523 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)Homo sapienspyridoxine0.320.00745 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant A243GHomo sapiensadenosine 5'-triphosphatePLP formation followed directly at 388 nm (1 µM enzyme)—1.024—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant A243GHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PN—0.132—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant A243GHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PM—0.0341—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant A243GHomo sapienspyridoxal0.470.1772.6 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant A243GHomo sapienspyridoxamine0.0830.03192.6 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant A243GHomo sapienspyridoxine0.30.009233 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant D87HHomo sapiensadenosine 5'-triphosphatePLP formation followed directly at 388 nm (1 µM enzyme)—0.377—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant D87HHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PN—0.125—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant D87HHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PM—0.0553—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant D87HHomo sapienspyridoxal0.672.090.32 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant D87HHomo sapienspyridoxamine0.120.02654.5 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant D87HHomo sapienspyridoxine0.350.034110 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant H246QHomo sapiensadenosine 5'-triphosphatePLP formation followed directly at 388 nm (1 µM enzyme)—0.901—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant H246QHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PN—0.126—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant H246QHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PM—0.0768—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant H246QHomo sapienspyridoxal0.580.1414.1 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant H246QHomo sapienspyridoxamine0.1050.03463.00 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant H246QHomo sapienspyridoxine0.280.011525 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant V128IHomo sapiensadenosine 5'-triphosphatePLP formation followed directly at 388 nm (1 µM enzyme)—3.096—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant V128IHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PN—0.113—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant V128IHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PM—0.0563—pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant V128IHomo sapienspyridoxal1.123.8390.290 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant V128IHomo sapienspyridoxamine0.1420.05152.80 calc.pH 7.3, 37 °COpen
pyridoxal kinase (PDXK)variant V128IHomo sapienspyridoxine0.330.024813 calc.pH 7.3, 37 °COpen