CatLogenzyme kinetics catalog

EC 2.7.1.35: pyridoxal kinase

TransferasesOpen in Browse

CatLog read 62 records for EC 2.7.1.35 from 4 papers, for 2 organisms. Names in these papers: pyridoxal kinase (PDXK), pyridoxal kinase 1 (ePL kinase 1), pyridoxal kinase (hPL kinase), pyridoxal kinase and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 41 records for EC 2.7.1.35 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.1.35 in Browse.

Papers

PaperOrganismsRecords
The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrityHomo sapiens30
Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinasesEscherichia coli, Homo sapiens21
Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinaseHomo sapiens6
The human pyridoxal kinase, a plausible target for ginkgotoxin from Ginkgo bilobaHomo sapiens5

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
pyridoxal kinaseHomo sapiensMgATP—0.19—pH 7.2, 37 °CPMID 19351586Open
pyridoxal kinaseHomo sapienspyridoxal0.480.02420 calc.pH 7.2, 37 °CPMID 19351586Open
pyridoxal kinasevariant D235AHomo sapiensMgATP—0.17—pH 7.2, 37 °CPMID 19351586Open
pyridoxal kinasevariant D235AHomo sapienspyridoxal0.0320.170.19 calc.pH 7.2, 37 °CPMID 19351586Open
pyridoxal kinasevariant D235NHomo sapiensMgATP—0.18—pH 7.2, 37 °CPMID 19351586Open
pyridoxal kinasevariant D235NHomo sapienspyridoxal0.230.0584.0 calc.pH 7.2, 37 °CPMID 19351586Open
pyridoxal kinase (hPL kinase)Homo sapiensATPdirect assay: PLP formation followed at 388 nm—0.42—pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase (hPL kinase)Homo sapiensATPstopped with EDTA/boiling; cosubstrate PN—0.21—pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase (hPL kinase)Homo sapiensATPstopped with EDTA/boiling; cosubstrate PM—0.33—pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase (hPL kinase)Homo sapienspyridoxalcosubstrate MgATP0.750.0325 calc.pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase (hPL kinase)Homo sapienspyridoxalcosubstrate ZnATP0.50.351.4 calc.pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase (hPL kinase)Homo sapienspyridoxamine0.330.0359.5 calc.pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase (hPL kinase)Homo sapienspyridoxinecosubstrate MgATP0.330.0217 calc.pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase (hPL kinase)Homo sapienspyridoxinecosubstrate ZnATP0.120.0157.8 calc.pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase (PDXK)Homo sapiensadenosine 5'-triphosphatePLP formation followed directly at 388 nm (1 µM enzyme)—0.407—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)Homo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PN—0.104—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)Homo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PM—0.0462—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)Homo sapienspyridoxal0.970.1895.1 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)Homo sapienspyridoxamine0.1150.00523 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)Homo sapienspyridoxine0.320.00745 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant A243GHomo sapiensadenosine 5'-triphosphatePLP formation followed directly at 388 nm (1 µM enzyme)—1.024—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant A243GHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PN—0.132—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant A243GHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PM—0.0341—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant A243GHomo sapienspyridoxal0.470.1772.6 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant A243GHomo sapienspyridoxamine0.0830.03192.6 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant A243GHomo sapienspyridoxine0.30.009233 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant D87HHomo sapiensadenosine 5'-triphosphatePLP formation followed directly at 388 nm (1 µM enzyme)—0.377—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant D87HHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PN—0.125—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant D87HHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PM—0.0553—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant D87HHomo sapienspyridoxal0.672.090.32 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant D87HHomo sapienspyridoxamine0.120.02654.5 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant D87HHomo sapienspyridoxine0.350.034110 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant H246QHomo sapiensadenosine 5'-triphosphatePLP formation followed directly at 388 nm (1 µM enzyme)—0.901—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant H246QHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PN—0.126—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant H246QHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PM—0.0768—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant H246QHomo sapienspyridoxal0.580.1414.1 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant H246QHomo sapienspyridoxamine0.1050.03463.00 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant H246QHomo sapienspyridoxine0.280.011525 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant V128IHomo sapiensadenosine 5'-triphosphatePLP formation followed directly at 388 nm (1 µM enzyme)—3.096—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant V128IHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PN—0.113—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant V128IHomo sapiensadenosine 5'-triphosphatePLP followed at 388 nm; cosubstrate PM—0.0563—pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant V128IHomo sapienspyridoxal1.123.8390.290 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant V128IHomo sapienspyridoxamine0.1420.05152.80 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PDXK)variant V128IHomo sapienspyridoxine0.330.024813 calc.pH 7.3, 37 °CPMID 31578392Open
pyridoxal kinase (PKH)Homo sapiens4'-deoxypyridoxine1.5350.021671pH 6.2, 37 °CPMID 17250738Open
pyridoxal kinase (PKH)Homo sapiens4'-O-methylpyridoxine0.460.0049593pH 6.2, 37 °CPMID 17250738Open
pyridoxal kinase (PKH)Homo sapiensPyridoxal0.9950.058717pH 6.2, 37 °CPMID 17250738Open
pyridoxal kinase (PKH)Homo sapiensPyridoxamine0.790.1266.28pH 6.2, 37 °CPMID 17250738Open
pyridoxal kinase (PKH)Homo sapiensPyridoxine1.2330.00987125pH 6.2, 37 °CPMID 17250738Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia coliATPdirect assay: PLP formation followed at 388 nm—0.6—pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia coliATP—2.1—pH 6.1, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia coliATPstopped with EDTA/boiling; cosubstrate PN—0.65—pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia coliATPstopped with EDTA/boiling; cosubstrate PM—0.6—pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia coliATPdirect assay: PLP formation followed at 388 nm—0.07—pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia coliATPstopped with EDTA/boiling; cosubstrate PM—0.045—pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia colipyridoxalcosubstrate MgATP2.30.123 calc.pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia colipyridoxalcosubstrate MgATP20.365.6 calc.pH 6.1, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia colipyridoxalcosubstrate ZnATP20.1911 calc.pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia colipyridoxalcosubstrate ZnATP—0.13—pH 6.1, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia colipyridoxaminecosubstrate MgATP0.670.0322 calc.pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia colipyridoxaminecosubstrate ZnATP0.420.0142 calc.pH 7.3, 37 °CPMID 15249053Open
pyridoxal kinase 1 (ePL kinase 1)Escherichia colipyridoxine0.330.02513 calc.pH 7.3, 37 °CPMID 15249053Open