CatLogenzyme kinetics catalog

Values CatLog read from this paper

Catalytic mechanism of the cyclohydrolase activity of human aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase

PMID 14756554doi:10.1021/bi035139bOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 11 records (29 values) from this paper: aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activity from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.1.2.3, EC 3.5.4.10

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide8.69 × 10⁻⁴1 × 10⁴pH 7.5Open
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityvariant D125AHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide0.0140.00912pH 7.5Open
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityvariant D125EHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide0.1470.005230pH 7.5Open
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityvariant D125NHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide0.6030.0027200pH 7.5Open
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityvariant K137AHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide0.2760.0319pH 7.5Open
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityvariant K137RHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide0.5070.0027200pH 7.5Open
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityvariant K66AHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide0.0620.1150.5pH 7.5Open
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityvariant Y104AHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide0.1360.00350pH 7.5Open
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityvariant Y104A/D125AHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide0.001——pH 7.5Open
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityvariant Y104FHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide0.0360.003610pH 7.5Open
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), IMP cyclohydrolase (IMPCHase) activityvariant Y104F/D125AHomo sapiens5-formylaminoimidazole-4-carboxamide ribonucleotide8 × 10⁻⁴——pH 7.5Open