Values CatLog read from this paper
Structural basis for catalytic differences between alpha class human glutathione transferases hGSTA1-1 and hGSTA2-2 for glutathione conjugation of environmental carcinogen…
PMID 15274625doi:10.1021/bi049435fOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 21 records (63 values) from this paper: hGSTA2-2, hGSTA1-1 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| hGSTA1-1 | Homo sapiens | (-)-anti-BPDE | 0.019 | 0.046 | 0.41 | pH 7.5, 37 °C | Open record: hGSTA1-1, (-)-anti-BPDE |
| hGSTA1-1 | Homo sapiens | (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene | 0.05 | 0.047 | 1.1 | pH 7.5, 37 °C | Open record: hGSTA1-1, (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene |
| hGSTA1-1 | Homo sapiens | 1-chloro-2,4-dinitrobenzene | 46 | 0.3 | 153 | 25 °C | Open record: hGSTA1-1, 1-chloro-2,4-dinitrobenzene |
| hGSTA2-2 | Homo sapiens | (-)-anti-BPDE | 0.021 | 0.123 | 0.18 | pH 7.5, 37 °C | Open record: hGSTA2-2, (-)-anti-BPDE |
| hGSTA2-2 | Homo sapiens | (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene | 0.02 | 0.098 | 0.2 | pH 7.5, 37 °C | Open record: hGSTA2-2, (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene |
| hGSTA2-2 | Homo sapiens | 1-chloro-2,4-dinitrobenzene | 15 | 0.5 | 30 | 25 °C | Open record: hGSTA2-2, 1-chloro-2,4-dinitrobenzene |
| hGSTA2-2variant F110V | Homo sapiens | (-)-anti-BPDE | 0.011 | 0.036 | 0.3 | pH 7.5, 37 °C | Open record: hGSTA2-2 variant F110V, (-)-anti-BPDE |
| hGSTA2-2variant F110V | Homo sapiens | (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene | 0.012 | 0.036 | 0.3 | pH 7.5, 37 °C | Open record: hGSTA2-2 variant F110V, (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene |
| hGSTA2-2variant F110V | Homo sapiens | 1-chloro-2,4-dinitrobenzene | 71 | 5.4 | 13 | 25 °C | Open record: hGSTA2-2 variant F110V, 1-chloro-2,4-dinitrobenzene |
| hGSTA2-2variant I11A | Homo sapiens | (-)-anti-BPDE | 0.009 | 0.096 | 0.09 | pH 7.5, 37 °C | Open record: hGSTA2-2 variant I11A, (-)-anti-BPDE |
| hGSTA2-2variant I11A | Homo sapiens | (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene | 0.05 | 0.035 | 1.4 | pH 7.5, 37 °C | Open record: hGSTA2-2 variant I11A, (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene |
| hGSTA2-2variant I11A | Homo sapiens | 1-chloro-2,4-dinitrobenzene | 2.6 | 0.06 | 43 | 25 °C | Open record: hGSTA2-2 variant I11A, 1-chloro-2,4-dinitrobenzene |
| hGSTA2-2variant S215A | Homo sapiens | (-)-anti-BPDE | 0.008 | 0.214 | 0.04 | pH 7.5, 37 °C | Open record: hGSTA2-2 variant S215A, (-)-anti-BPDE |
| hGSTA2-2variant S215A | Homo sapiens | (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene | 0.008 | 0.143 | 0.06 | pH 7.5, 37 °C | Open record: hGSTA2-2 variant S215A, (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene |
| hGSTA2-2variant S215A | Homo sapiens | 1-chloro-2,4-dinitrobenzene | 17 | 0.3 | 57 | 25 °C | Open record: hGSTA2-2 variant S215A, 1-chloro-2,4-dinitrobenzene |
| hGSTA2-2variant S9F | Homo sapiens | (-)-anti-BPDE | 0.006 | 0.043 | 0.13 | pH 7.5, 37 °C | Open record: hGSTA2-2 variant S9F, (-)-anti-BPDE |
| hGSTA2-2variant S9F | Homo sapiens | (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene | 0.01 | 0.049 | 0.2 | pH 7.5, 37 °C | Open record: hGSTA2-2 variant S9F, (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene |
| hGSTA2-2variant S9F | Homo sapiens | 1-chloro-2,4-dinitrobenzene | 44 | 1.6 | 28 | 25 °C | Open record: hGSTA2-2 variant S9F, 1-chloro-2,4-dinitrobenzene |
| hGSTA2-2variant S9F/I11A/F110V/S215A | Homo sapiens | (-)-anti-BPDE | 0.027 | 0.011 | 2.5 | pH 7.5, 37 °C | Open record: hGSTA2-2 variant S9F/I11A/F110V/S215A, (-)-anti-BPDE |
| hGSTA2-2variant S9F/I11A/F110V/S215A | Homo sapiens | (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene | 0.06 | 0.022 | 2.7 | pH 7.5, 37 °C | Open record: hGSTA2-2 variant S9F/I11A/F110V/S215A, (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene |
| hGSTA2-2variant S9F/I11A/F110V/S215A | Homo sapiens | 1-chloro-2,4-dinitrobenzene | 8 | 0.2 | 40 | 25 °C | Open record: hGSTA2-2 variant S9F/I11A/F110V/S215A, 1-chloro-2,4-dinitrobenzene |