Values CatLog read from this paper
The interactions in the carboxyl terminus of human 4-hydroxyphenylpyruvate dioxygenase are critical to mediate the conformation of the final helix and the tail to shield the active site for…
PMID 23950902doi:10.1371/journal.pone.0069733Open in Browse
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CatLog read 8 records (24 values) from this paper: 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) | Homo sapiens | 4-hydroxyphenylpyruvate | 2.2 | 0.08 | 29 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (4-HPPD), 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (4-HPPD)variant E254D | Homo sapiens | 4-hydroxyphenylpyruvate | 0.06 | 0.11 | 0.57 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) variant E254D, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (4-HPPD)variant R378K | Homo sapiens | 4-hydroxyphenylpyruvate | 0.07 | 0.24 | 0.27 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) variant R378K, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (4-HPPD)variant ΔE385 (printed ΔL385 in Table 4) | Homo sapiens | 4-hydroxyphenylpyruvate | 1.4 | 0.09 | 16 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) variant ΔE385 (printed ΔL385 in Table 4), 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (4-HPPD)variant ΔG379 | Homo sapiens | 4-hydroxyphenylpyruvate | 0.1 | 0.12 | 0.9 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) variant ΔG379, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (4-HPPD)variant ΔG388 | Homo sapiens | 4-hydroxyphenylpyruvate | 1.4 | 0.08 | 17 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) variant ΔG388, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (4-HPPD)variant ΔL381 | Homo sapiens | 4-hydroxyphenylpyruvate | 1 | 0.07 | 14 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) variant ΔL381, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (4-HPPD)variant ΔN380 | Homo sapiens | 4-hydroxyphenylpyruvate | 0.5 | 0.3 | 1.5 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) variant ΔN380, 4-hydroxyphenylpyruvate |