Values CatLog read from this paper
Analysis of Fasciola cathepsin L5 by S2 subsite substitutions and determination of the P1-P4 specificity reveals an unusual preference
PMID 22285967doi:10.1016/j.biochi.2012.01.011Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (36 values) from this paper: cathepsin L5 (FhCatL5), cathepsin L2 (FhCatL2) from Fasciola hepatica.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cathepsin L2 (FhCatL2) | Fasciola hepatica | Tosyl-Gly-Pro-Arg-AMC | 7.08 | 0.03615 | 196 | pH 5.5, 37 °C | Open record: cathepsin L2 (FhCatL2), Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L2 (FhCatL2) | Fasciola hepatica | Z-Phe-Arg-AMC | 5.17 | 0.02257 | 229 | pH 5.5, 37 °C | Open record: cathepsin L2 (FhCatL2), Z-Phe-Arg-AMC |
| cathepsin L2 (FhCatL2)variant Y69L | Fasciola hepatica | Tosyl-Gly-Pro-Arg-AMC | 2.19 | 0.05471 | 40.1 | pH 5.5, 37 °C | Open record: cathepsin L2 (FhCatL2) variant Y69L, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L2 (FhCatL2)variant Y69L | Fasciola hepatica | Z-Phe-Arg-AMC | 5.22 | 0.05008 | 104 | pH 5.5, 37 °C | Open record: cathepsin L2 (FhCatL2) variant Y69L, Z-Phe-Arg-AMC |
| cathepsin L5 (FhCatL5)variant L69C | Fasciola hepatica | Tosyl-Gly-Pro-Arg-AMC | 0.19 | 0.07674 | 2.5 | pH 5.5, 37 °C | Open record: cathepsin L5 (FhCatL5) variant L69C, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L5 (FhCatL5)variant L69C | Fasciola hepatica | Z-Phe-Arg-AMC | 1.92 | 0.01372 | 140 | pH 5.5, 37 °C | Open record: cathepsin L5 (FhCatL5) variant L69C, Z-Phe-Arg-AMC |
| cathepsin L5 (FhCatL5)variant L69F | Fasciola hepatica | Tosyl-Gly-Pro-Arg-AMC | 1.78 | 0.05193 | 34.4 | pH 5.5, 37 °C | Open record: cathepsin L5 (FhCatL5) variant L69F, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L5 (FhCatL5)variant L69F | Fasciola hepatica | Z-Phe-Arg-AMC | 17.93 | 0.01911 | 938 | pH 5.5, 37 °C | Open record: cathepsin L5 (FhCatL5) variant L69F, Z-Phe-Arg-AMC |
| cathepsin L5 (FhCatL5)variant L69S | Fasciola hepatica | Tosyl-Gly-Pro-Arg-AMC | 0.27 | 0.1269 | 2.1 | pH 5.5, 37 °C | Open record: cathepsin L5 (FhCatL5) variant L69S, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L5 (FhCatL5)variant L69S | Fasciola hepatica | Z-Phe-Arg-AMC | 1.73 | 0.01272 | 136 | pH 5.5, 37 °C | Open record: cathepsin L5 (FhCatL5) variant L69S, Z-Phe-Arg-AMC |
| cathepsin L5 (FhCatL5)variant L69Y | Fasciola hepatica | Tosyl-Gly-Pro-Arg-AMC | 2.54 | 0.06346 | 40 | pH 5.5, 37 °C | Open record: cathepsin L5 (FhCatL5) variant L69Y, Tosyl-Gly-Pro-Arg-AMC |
| cathepsin L5 (FhCatL5)variant L69Y | Fasciola hepatica | Z-Phe-Arg-AMC | 21.52 | 0.03287 | 655 | pH 5.5, 37 °C | Open record: cathepsin L5 (FhCatL5) variant L69Y, Z-Phe-Arg-AMC |