CatLogenzyme kinetics catalog

Values CatLog read from this paper

Kinetic modeling of beta-chloroprene metabolism: I. In vitro rates in liver and lung tissue fractions from mice, rats, hamsters, and humans

PMID 14976339doi:10.1093/toxsci/kfh092Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 18 records (18 values) from this paper: microsomal epoxide hydrolase, cytochrome P450 from Mus musculus, Rattus norvegicus, Homo sapiens and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.3.2.9

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
cytochrome P450Homo sapiens2-chloro-1,3-butadiene—6.8 × 10⁻⁴—pH 7.4, 37 °COpen
cytochrome P450Mus musculus(1-chloroethenyl)oxirane—0.0168—pH 7.4Open
cytochrome P450Mus musculus2-chloro-1,3-butadiene—0.00103—pH 7.4, 37 °COpen
cytochrome P450Mus musculus2-chloro-1,3-butadienelung microsomes prepared in-house from B6C3F1 mice—0.0015—pH 7.4, 37 °COpen
cytochrome P450Rattus norvegicus2-chloro-1,3-butadieneFischer F344—5.3 × 10⁻⁴—pH 7.4, 37 °COpen
cytochrome P450Rattus norvegicus2-chloro-1,3-butadieneWistar—8.4 × 10⁻⁴—pH 7.4, 37 °COpen
cytochrome P450Syrian hamster2-chloro-1,3-butadiene—0.00133—pH 7.4, 37 °COpen
microsomal epoxide hydrolaseHomo sapiens(1-chloroethenyl)oxirane—0.0997—pH 7.4Open
microsomal epoxide hydrolaseHomo sapiens(1-chloroethenyl)oxirane—0.0722—pH 7.4Open
microsomal epoxide hydrolaseMus musculus(1-chloroethenyl)oxiranemicrosomal protein 0.5 mg/ml; no NADP+; Table 2—0.0209—pH 7.4Open
microsomal epoxide hydrolaseMus musculus(1-chloroethenyl)oxiranemicrosomal protein 0.5 mg/ml; no NADP+; Table 2—0.0515—pH 7.4Open
microsomal epoxide hydrolaseMus musculus(1-chloroethenyl)oxiranewith NADP+ added 10 s before the microsomal protein—0.0854—pH 7.4Open
microsomal epoxide hydrolaseRattus norvegicus(1-chloroethenyl)oxirane—0.0415—pH 7.4Open
microsomal epoxide hydrolaseRattus norvegicus(1-chloroethenyl)oxirane—0.053—pH 7.4Open
microsomal epoxide hydrolaseRattus norvegicus(1-chloroethenyl)oxiranelung microsomes prepared in-house from Fischer F344 rats—0.0909—pH 7.4Open
microsomal epoxide hydrolaseRattus norvegicus(1-chloroethenyl)oxiranelung microsomes prepared in-house from Wistar rats—0.0916—pH 7.4Open
microsomal epoxide hydrolaseSyrian hamster(1-chloroethenyl)oxirane—0.0738—pH 7.4Open
microsomal epoxide hydrolaseSyrian hamster(1-chloroethenyl)oxirane—0.1876—pH 7.4Open