Values CatLog read from this paper
Family-wide analysis of human macrodomains reveals novel activities and identifies PARG as most efficient ADPr-RNA hydrolase
PMID 40102620doi:10.1038/s42003-025-07901-7Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 3 records (3 values) from this paper: PARG (catalytic domain, PARGcat), MACROD2 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| MACROD2 | Homo sapiens | 5'-ADP-ribosylated single-stranded RNA oligonucleotide 5'P-GUUUCGGAUCGACGC-3'-Cy3 | 1.25 | — | — | pH 7.6, 37 °C | Open record: MACROD2, 5'-ADP-ribosylated single-stranded RNA oligonucleotide 5'P-GUUUCGGAUCGACGC-3'-Cy3 |
| PARG (catalytic domain, PARGcat) | Homo sapiens | 5'-ADP-ribosylated single-stranded RNA oligonucleotide 5'P-GUUUCGGAUCGACGC-3'-Cy3 | 46.7 | — | — | pH 7.6, 37 °C | Open record: PARG (catalytic domain, PARGcat), 5'-ADP-ribosylated single-stranded RNA oligonucleotide 5'P-GUUUCGGAUCGACGC-3'-Cy3 |
| PARG (catalytic domain, PARGcat)variant E755A | Homo sapiens | 5'-ADP-ribosylated single-stranded RNA oligonucleotide 5'P-GUUUCGGAUCGACGC-3'-Cy3 | 0.071 | — | — | pH 7.6, 37 °C | Open record: PARG (catalytic domain, PARGcat) variant E755A, 5'-ADP-ribosylated single-stranded RNA oligonucleotide 5'P-GUUUCGGAUCGACGC-3'-Cy3 |