EC 3.2.1.143: poly(ADP-ribose) glycohydrolase
HydrolasesOpen in Browse
CatLog read 2 records for EC 3.2.1.143 from 1 paper, for 1 organism. Names in these papers: PARG (catalytic domain, PARGcat).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 9 records for EC 3.2.1.143 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.2.1.143 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Family-wide analysis of human macrodomains reveals novel activities and identifies PARG as most efficient ADPr-RNA hydrolase | Homo sapiens | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| PARG (catalytic domain, PARGcat) | Homo sapiens | 5'-ADP-ribosylated single-stranded RNA oligonucleotide 5'P-GUUUCGGAUCGACGC-3'-Cy3 | 46.7 | — | — | pH 7.6, 37 °C | PMID 40102620 | Open record: PARG (catalytic domain, PARGcat), 5'-ADP-ribosylated single-stranded RNA oligonucleotide 5'P-GUUUCGGAUCGACGC-3'-Cy3 |
| PARG (catalytic domain, PARGcat)variant E755A | Homo sapiens | 5'-ADP-ribosylated single-stranded RNA oligonucleotide 5'P-GUUUCGGAUCGACGC-3'-Cy3 | 0.071 | — | — | pH 7.6, 37 °C | PMID 40102620 | Open record: PARG (catalytic domain, PARGcat) variant E755A, 5'-ADP-ribosylated single-stranded RNA oligonucleotide 5'P-GUUUCGGAUCGACGC-3'-Cy3 |