Values CatLog read from this paper
Structural and functional modulation of human kynurenine aminotransferase I enhances selenium-driven redox metabolism for cancer therapy
PMID 41412036doi:10.1016/j.redox.2025.103967Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 44 records (132 values) from this paper: kynurenine aminotransferase 1 (hKYAT1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 2.6.1.7, EC 2.6.1.64, EC 4.4.1.13
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| kynurenine aminotransferase 1 (hKYAT1) | Homo sapiens | L-kynurenine | 2147 | 1.7 | 1263 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1), L-kynurenine |
| kynurenine aminotransferase 1 (hKYAT1) | Homo sapiens | L-phenylalanine | 13,301 | 1.6 | 8313 | pH 9, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1), L-phenylalanine |
| kynurenine aminotransferase 1 (hKYAT1) | Homo sapiens | L-tryptophan | 3861 | 0.8 | 4826 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1), L-tryptophan |
| kynurenine aminotransferase 1 (hKYAT1) | Homo sapiens | Se-methylselenocysteine | 1.836 × 10⁴ | 24.3 | 756 | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1), Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1) | Homo sapiens | Se-methylselenocysteine | 18,946 | 11.6 | 1633 | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1), Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1) | Homo sapiens | selenomethionine | 2668 | 17.9 | 149 | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1), selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1) | Homo sapiens | selenomethionine | 18,142 | 0.5 | 36,284 | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1), selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1)variant D126L | Homo sapiens | L-kynurenine | 20,661 | 11 | 1878 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant D126L, L-kynurenine |
| kynurenine aminotransferase 1 (hKYAT1)variant D126L | Homo sapiens | L-phenylalanine | 3925 | 3.1 | 1266 | pH 9, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant D126L, L-phenylalanine |
| kynurenine aminotransferase 1 (hKYAT1)variant D126L | Homo sapiens | L-tryptophan | 1.353 × 10⁴ | 11.7 | 1156 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant D126L, L-tryptophan |
| kynurenine aminotransferase 1 (hKYAT1)variant D126L | Homo sapiens | Se-methylselenocysteine | 1543 | 1.6 | 964 | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant D126L, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant D126L | Homo sapiens | Se-methylselenocysteine | 21,273 | 11.9 | 1788 | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1) variant D126L, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant D126L | Homo sapiens | selenomethionine | 343 | 0.1 | 3.43 × 10³ | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant D126L, selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1)variant D126L | Homo sapiens | selenomethionine | 5.26 × 10³ | 0.3 | 17,533 | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1) variant D126L, selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1)variant F278A | Homo sapiens | L-phenylalanine | 1.191 × 10⁵ | 4.9 | 2.43 × 10⁴ | pH 9, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant F278A, L-phenylalanine |
| kynurenine aminotransferase 1 (hKYAT1)variant F278A | Homo sapiens | L-tryptophan | 1.572 × 10⁴ | 2.2 | 7145 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant F278A, L-tryptophan |
| kynurenine aminotransferase 1 (hKYAT1)variant F278A | Homo sapiens | Se-methylselenocysteine | 5249 | 0.1 | 5.249 × 10⁴ | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant F278A, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant F278A | Homo sapiens | Se-methylselenocysteine | 26,104 | 9.7 | 2691 | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1) variant F278A, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant F278A | Homo sapiens | selenomethionine | 9399 | 141.8 | 66 | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant F278A, selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1)variant F278A | Homo sapiens | selenomethionine | 9643 | 0.03 | 3.214 × 10⁵ | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1) variant F278A, selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H | Homo sapiens | L-kynurenine | 6988 | 3.7 | 1889 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H, L-kynurenine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H | Homo sapiens | L-phenylalanine | 17,026 | 4.8 | 3547 | pH 9, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H, L-phenylalanine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H | Homo sapiens | L-tryptophan | 5881 | 1.4 | 4201 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H, L-tryptophan |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H | Homo sapiens | Se-methylselenocysteine | 4526 | 0.1 | 4.526 × 10⁴ | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H | Homo sapiens | Se-methylselenocysteine | 20,315 | 7 | 2902 | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H | Homo sapiens | selenomethionine | 5503 | 29.6 | 186 | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H, selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H | Homo sapiens | selenomethionine | 1.419 × 10⁴ | 0.3 | 4.73 × 10⁴ | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H, selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H/H279F | Homo sapiens | L-kynurenine | 255 | 0.14 | 1821 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H/H279F, L-kynurenine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H/H279F | Homo sapiens | L-phenylalanine | 4937 | 2.3 | 2147 | pH 9, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H/H279F, L-phenylalanine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H/H279F | Homo sapiens | L-tryptophan | 3981 | 13.7 | 291 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H/H279F, L-tryptophan |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H/H279F | Homo sapiens | Se-methylselenocysteine | 2522 | 0.2 | 1.261 × 10⁴ | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H/H279F, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H/H279F | Homo sapiens | Se-methylselenocysteine | 13,257 | 8.4 | 1578 | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H/H279F, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H/H279F | Homo sapiens | selenomethionine | 1051 | 7.2 | 146 | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H/H279F, selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101H/H279F | Homo sapiens | selenomethionine | 1.042 × 10⁴ | 0.6 | 17,367 | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101H/H279F, selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101N/H279F | Homo sapiens | L-phenylalanine | 3154 | 1.8 | 1752 | pH 9, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101N/H279F, L-phenylalanine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101N/H279F | Homo sapiens | Se-methylselenocysteine | 18,461 | 26.8 | 689 | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101N/H279F, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101N/H279F | Homo sapiens | Se-methylselenocysteine | 21,359 | 8.2 | 2605 | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101N/H279F, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101N/H279F | Homo sapiens | selenomethionine | 236 | 4.2 | 56 | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101N/H279F, selenomethionine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101Q/F125Y | Homo sapiens | L-kynurenine | 2234 | 1.2 | 1862 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101Q/F125Y, L-kynurenine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101Q/F125Y | Homo sapiens | L-phenylalanine | 7842 | 1.2 | 6535 | pH 9, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101Q/F125Y, L-phenylalanine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101Q/F125Y | Homo sapiens | L-tryptophan | 7869 | 3.2 | 2459 | pH 9.6, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101Q/F125Y, L-tryptophan |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101Q/F125Y | Homo sapiens | Se-methylselenocysteine | 1639 | 5.1 | 321 | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101Q/F125Y, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101Q/F125Y | Homo sapiens | Se-methylselenocysteine | 56,793 | 48.7 | 1166 | pH 7.4 | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101Q/F125Y, Se-methylselenocysteine |
| kynurenine aminotransferase 1 (hKYAT1)variant Y101Q/F125Y | Homo sapiens | selenomethionine | 2213 | 3.8 | 582 | pH 7.4, 37 °C | Open record: kynurenine aminotransferase 1 (hKYAT1) variant Y101Q/F125Y, selenomethionine |