Values CatLog read from this paper
Sepiapterin reductase mediates chemical redox cycling in lung epithelial cells
PMID 23640889doi:10.1074/jbc.m112.402164Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 27 records (80 values) from this paper: sepiapterin reductase from Homo sapiens, Mus musculus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 1 kcat/Km value marked “calc.” from kcat and Km; no printed kcat/Km was read for that record.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| sepiapterin reductase | Homo sapiens | 1,2-naphthoquinone | 0.2767 | 0.0021 | 131.8 | pH 7.8 | Open record: sepiapterin reductase, 1,2-naphthoquinone |
| sepiapterin reductase | Homo sapiens | 1,4-naphthoquinone | 0.0472 | 0.027 | 1.75 | pH 7.8 | Open record: sepiapterin reductase, 1,4-naphthoquinone |
| sepiapterin reductase | Homo sapiens | 2,3-dimethoxy-1,4-naphthoquinone | 0.0052 | 0.086 | 0.067 | pH 7.8 | Open record: sepiapterin reductase, 2,3-dimethoxy-1,4-naphthoquinone |
| sepiapterin reductase | Homo sapiens | 2-methylnaphthalene-1,4-dione | 0.016 | 0.0872 | 0.18 | pH 7.8 | Open record: sepiapterin reductase, 2-methylnaphthalene-1,4-dione |
| sepiapterin reductase | Homo sapiens | 9,10-phenanthrenequinone | 0.6278 | 0.0088 | 71.3 | pH 7.8 | Open record: sepiapterin reductase, 9,10-phenanthrenequinone |
| sepiapterin reductase | Homo sapiens | L-sepiapterin | 1.617 | 0.0254 | 63.7 | pH 6.4, 37 °C | Open record: sepiapterin reductase, L-sepiapterin |
| sepiapterin reductase | Homo sapiens | NADH | 0.0033 | 0.11 | 0.033 | pH 7.8 | Open record: sepiapterin reductase, NADH |
| sepiapterin reductase | Homo sapiens | NADPH | 0.0123 | 0.0302 | 0.42 | pH 7.8 | Open record: sepiapterin reductase, NADPH |
| sepiapterin reductasevariant D257H | Homo sapiens | 9,10-phenanthrenequinone | 0.1073 | 0.0019 | 56.5 | pH 7.8 | Open record: sepiapterin reductase variant D257H, 9,10-phenanthrenequinone |
| sepiapterin reductasevariant D257H | Homo sapiens | L-sepiapterin | 0.157 | 0.0606 | 2.7 | pH 6.4, 37 °C | Open record: sepiapterin reductase variant D257H, L-sepiapterin |
| sepiapterin reductasevariant G14S | Homo sapiens | 9,10-phenanthrenequinone | 0.0057 | 0.0501 | 0.17 | pH 7.8 | Open record: sepiapterin reductase variant G14S, 9,10-phenanthrenequinone |
| sepiapterin reductasevariant G18D | Homo sapiens | 9,10-phenanthrenequinone | 0.0483 | 0.4641 | 0.17 | pH 7.8 | Open record: sepiapterin reductase variant G18D, 9,10-phenanthrenequinone |
| sepiapterin reductasevariant K174L | Homo sapiens | 9,10-phenanthrenequinone | 0.0298 | 0.0277 | 1 | pH 7.8 | Open record: sepiapterin reductase variant K174L, 9,10-phenanthrenequinone |
| sepiapterin reductasevariant K174L | Homo sapiens | L-sepiapterin | 0.09 | 0.1698 | 0.5 | pH 6.4, 37 °C | Open record: sepiapterin reductase variant K174L, L-sepiapterin |
| sepiapterin reductasevariant M205G | Homo sapiens | 9,10-phenanthrenequinone | 0.2242 | 0.0134 | 18 | pH 7.8 | Open record: sepiapterin reductase variant M205G, 9,10-phenanthrenequinone |
| sepiapterin reductasevariant M205G | Homo sapiens | L-sepiapterin | 0.428 | 0.1338 | 3.2 | pH 6.4, 37 °C | Open record: sepiapterin reductase variant M205G, L-sepiapterin |
| sepiapterin reductasevariant N99A | Homo sapiens | 9,10-phenanthrenequinone | 0.29 | 0.126 | 2.3 | pH 7.8 | Open record: sepiapterin reductase variant N99A, 9,10-phenanthrenequinone |
| sepiapterin reductasevariant N99A | Homo sapiens | L-sepiapterin | 0.055 | 0.0941 | 0.67 | pH 6.4, 37 °C | Open record: sepiapterin reductase variant N99A, L-sepiapterin |
| sepiapterin reductasevariant R42G | Homo sapiens | 9,10-phenanthrenequinone | 0.0983 | 0.0501 | 5.3 | pH 7.8 | Open record: sepiapterin reductase variant R42G, 9,10-phenanthrenequinone |
| sepiapterin reductasevariant R42G | Homo sapiens | L-sepiapterin | 0.053 | 0.0457 | 1.2 | pH 6.4, 37 °C | Open record: sepiapterin reductase variant R42G, L-sepiapterin |
| sepiapterin reductasevariant S157A | Homo sapiens | 9,10-phenanthrenequinone | 0.0153 | 0.0032 | 4.8 | pH 7.8 | Open record: sepiapterin reductase variant S157A, 9,10-phenanthrenequinone |
| sepiapterin reductasevariant S157A | Homo sapiens | L-sepiapterin | 0.058 | 0.0503 | 1.2 | pH 6.4, 37 °C | Open record: sepiapterin reductase variant S157A, L-sepiapterin |
| sepiapterin reductasevariant Y259A | Homo sapiens | 9,10-phenanthrenequinone | 0.805 | 0.0196 | 41 | pH 7.8 | Open record: sepiapterin reductase variant Y259A, 9,10-phenanthrenequinone |
| sepiapterin reductasevariant Y259A | Homo sapiens | L-sepiapterin | 0.603 | 0.0255 | 23.7 | pH 6.4, 37 °C | Open record: sepiapterin reductase variant Y259A, L-sepiapterin |
| sepiapterin reductasevariant Δ257-261 | Homo sapiens | 9,10-phenanthrenequinone | 0.0058 | 0.116 | 0.050 calc. | pH 7.8 | Open record: sepiapterin reductase variant Δ257-261, 9,10-phenanthrenequinone |
| sepiapterin reductase | Mus musculus | 9,10-phenanthrenequinone | 0.222 | 0.0063 | 35 | pH 7.8 | Open record: sepiapterin reductase, 9,10-phenanthrenequinone |
| sepiapterin reductase | Mus musculus | L-sepiapterin | 0.807 | 0.0442 | 18 | pH 6.4, 37 °C | Open record: sepiapterin reductase, L-sepiapterin |