CatLogenzyme kinetics catalog

Values CatLog read from this paper

Residues specific for class III alcohol dehydrogenase. Site-directed mutagenesis of the human enzyme

PMID 7999766doi:10.1021/bi00254a017Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 68 records (68 values) from this paper: class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.1, EC 1.1.1.284

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiens1-octanol—0.5—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiens1-octanolkcat per subunit2.7——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiens1-octanol——5.3pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiens1-pentanol—20—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiens1-pentanolkcat per subunit2.5——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiens1-pentanol——0.125pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiens12-hydroxydodecanoic acid—0.06—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiens12-hydroxydodecanoic acidkcat per subunit2.7——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiens12-hydroxydodecanoic acid——45pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapienscyclohexanol——0.0013pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiensethanol——7.5 × 10⁻⁴pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiensNAD+—0.01—pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiensNAD+—0.07—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiensS-hydroxymethylglutathione—0.004—pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiensS-hydroxymethylglutathionekcat per subunit3.3——pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiensS-hydroxymethylglutathione——830pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiens1-octanol—0.3—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiens1-octanolkcat per subunit2.7——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiens1-octanol——8.8pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiens1-pentanol—11—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiens1-pentanolkcat per subunit2.2——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiens1-pentanol——0.2pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiens12-hydroxydodecanoic acid—0.06—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiens12-hydroxydodecanoic acidkcat per subunit2.7——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiens12-hydroxydodecanoic acid——45pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapienscyclohexanol——0.0012pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiensethanol——7.5 × 10⁻⁴pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiensNAD+—0.52—pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiensNAD+—0.3—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiensS-hydroxymethylglutathione—0.6—pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiensS-hydroxymethylglutathionekcat per subunit0.92——pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiensS-hydroxymethylglutathione——1.5pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiens1-octanol—0.1—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiens1-octanol0.5——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiens1-octanol——5pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiens1-pentanol—10—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiens1-pentanol0.5——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiens1-pentanol——0.05pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiens12-hydroxydodecanoic acid—0.02—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiens12-hydroxydodecanoic acidkcat per subunit0.42——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiens12-hydroxydodecanoic acid——20.8pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapienscyclohexanol——0.0013pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiensethanol——7.5 × 10⁻⁴pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiensNAD+—0.15—pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiensNAD+—0.15—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiensS-hydroxymethylglutathione—0.5—pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiensS-hydroxymethylglutathionekcat per subunit0.33——pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiensS-hydroxymethylglutathione——0.67pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant T48AHomo sapiensNAD+—0.62—pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant T48AHomo sapiensS-hydroxymethylglutathione—4.4—pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant T48AHomo sapiensS-hydroxymethylglutathionekcat per subunit0.5——pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant T48AHomo sapiensS-hydroxymethylglutathione——0.12pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiens1-octanol—0.5—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiens1-octanolkcat per subunit0.58——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiens1-octanol——1.2pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiens1-pentanol—20—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiens1-pentanolkcat per subunit0.58——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiens1-pentanol——0.028pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiens12-hydroxydodecanoic acid—0.04—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiens12-hydroxydodecanoic acid0.5——pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiens12-hydroxydodecanoic acid——12.5pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapienscyclohexanol——0.0012pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiensethanol——7.5 × 10⁻⁴pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiensNAD+—0.01—pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiensNAD+—0.07—pH 10, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiensS-hydroxymethylglutathione—0.004—pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiensS-hydroxymethylglutathionekcat per subunit0.67——pH 8, 24 °COpen
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiensS-hydroxymethylglutathione——170pH 8, 24 °COpen