CatLogenzyme kinetics catalog

EC 1.1.1.284: S-(hydroxymethyl)glutathione dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 34 records for EC 1.1.1.284 from 4 papers, for 3 organisms. Names in these papers: class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase), ADH3, FrxA, glutathione-dependent formaldehyde dehydrogenase (FALDH).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 42 records for EC 1.1.1.284 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.284 in Browse.

Papers

PaperOrganismsRecords
Residues specific for class III alcohol dehydrogenase. Site-directed mutagenesis of the human enzymeHomo sapiens16
Oxidation of alcohols and reduction of aldehydes derived from methyl- and dimethylpyrenes by cDNA-expressed human alcohol dehydrogenasesHomo sapiens11
FrxA is an S-nitrosoglutathione reductase enzyme that contributes to Helicobacter pylori pathogenicityHelicobacter pylori6
Enhanced formaldehyde detoxification by overexpression of glutathione-dependent formaldehyde dehydrogenase from ArabidopsisArabidopsis1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
ADH3Homo sapiens1-formyl-6-methylpyrene—0.0038—pH 7.5PMID 18242813Open
ADH3Homo sapiens1-formyl-8-methylpyrene—0.00149—pH 7.5PMID 18242813Open
ADH3Homo sapiens1-formylpyrene—5.5 × 10⁻⁴—pH 7.5PMID 18242813Open
ADH3Homo sapiens1-hydroxymethyl-6-methylpyrene—5.7 × 10⁻⁴—pH 10PMID 18242813Open
ADH3Homo sapiens1-hydroxymethyl-8-methylpyrene—3.1 × 10⁻⁴—pH 10PMID 18242813Open
ADH3Homo sapiens1-hydroxymethylpyrene—5.9 × 10⁻⁴—pH 10PMID 18242813Open
ADH3Homo sapiens2-FP—0.009—pH 7.5PMID 18242813Open
ADH3Homo sapiens2-hydroxymethylpyrene—0.106—pH 10PMID 18242813Open
ADH3Homo sapiens4-FP—0.0021—pH 7.5PMID 18242813Open
ADH3Homo sapiens4-hydroxymethylpyrene—3.7 × 10⁻⁴—pH 10PMID 18242813Open
ADH3Homo sapiensoctanal—1.9—pH 7.5PMID 18242813Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiensNAD+—0.01—pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiensS-hydroxymethylglutathione—0.004—pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiensS-hydroxymethylglutathionekcat per subunit3.3——pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)Homo sapiensS-hydroxymethylglutathione——830pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiensNAD+—0.52—pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiensS-hydroxymethylglutathione—0.6—pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiensS-hydroxymethylglutathionekcat per subunit0.92——pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57LHomo sapiensS-hydroxymethylglutathione——1.5pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiensS-hydroxymethylglutathionekcat per subunit0.33——pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant D57L/Y93FHomo sapiensS-hydroxymethylglutathione——0.67pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant T48AHomo sapiensNAD+—0.62—pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant T48AHomo sapiensS-hydroxymethylglutathione—4.4—pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiensNAD+—0.01—pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiensS-hydroxymethylglutathione—0.004—pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiensS-hydroxymethylglutathionekcat per subunit0.67——pH 8, 24 °CPMID 7999766Open
class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)variant Y93FHomo sapiensS-hydroxymethylglutathione——170pH 8, 24 °CPMID 7999766Open
FrxAHelicobacter pylori3-nitro-L-tyrosine0.10.06262.7pH 7.5PMID 25132107Open
FrxAHelicobacter pyloriMetronidazole0.60.022425pH 7.5PMID 25132107Open
FrxAHelicobacter pyloriNitrofurantoin0.50.042311pH 7.5PMID 25132107Open
FrxAHelicobacter pyloriNitrofurazone10.014371pH 7.5PMID 25132107Open
FrxAHelicobacter pyloriS-nitrosocysteine0.60.007289pH 7.5PMID 25132107Open
FrxAHelicobacter pyloriS-nitrosoglutathione0.50.0041126pH 7.5PMID 25132107Open
glutathione-dependent formaldehyde dehydrogenase (FALDH)ArabidopsisS-hydroxymethylglutathione22.520.0073.22 × 10³pH 8, 25 °CPMID 12913179Open