CatLogenzyme kinetics catalog

Values CatLog read from this paper

Effects of amino acid substitutions at positions 33 and 37 on UDP-glucuronosyltransferase 1A9 (UGT1A9) activity and substrate selectivity

PMID 22981363doi:10.1016/j.bcp.2012.08.026Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 36 records (36 values) from this paper: UDP-glucuronosyltransferase 1A9 (UGT1A9) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.4.1.17

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
UDP-glucuronosyltransferase 1A9 (UGT1A9)Homo sapiens4-methylumbelliferone—0.011—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)Homo sapiensfrusemide—0.229—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)Homo sapiensmycophenolic acid—0.087—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)Homo sapienspropofol—0.026—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)Homo sapiensretigabine—0.032—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)Homo sapienssulfinpyrazone—0.014—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant H37LHomo sapiensretigabine—0.06—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant H37PHomo sapiensretigabine—0.037—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant H37QHomo sapiensretigabine—0.035—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33IHomo sapiens(S)-naproxen—0.62—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33IHomo sapiens4-methylumbelliferone—0.233—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33IHomo sapiensfrusemide—0.187—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33IHomo sapiensmycophenolic acid—0.157—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33IHomo sapienspropofol—0.113—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33IHomo sapiensretigabine—0.099—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33IHomo sapienssulfinpyrazone—0.032—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33QHomo sapiens4-methylumbelliferone—0.228—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33QHomo sapiensfrusemide—0.183—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33QHomo sapiensmycophenolic acid—0.046—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33QHomo sapienspropofol—0.07—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33QHomo sapiensretigabine—0.055—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33QHomo sapienssulfinpyrazone—0.033—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33THomo sapiens(S)-naproxen—1.013—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33THomo sapiens4-methylumbelliferone—1.621—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33THomo sapiensfrusemide—0.209—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33THomo sapiensmycophenolic acid—0.336—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33THomo sapienspropofol—0.113—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33THomo sapiensretigabine—0.068—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33THomo sapienssulfinpyrazone—0.053—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33VHomo sapiens(S)-naproxen—0.507—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33VHomo sapiens4-methylumbelliferone—0.234—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33VHomo sapiensfrusemide—0.129—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33VHomo sapiensmycophenolic acid—0.2—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33VHomo sapienspropofol—0.109—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33VHomo sapiensretigabine—0.062—pH 7.4, 37 °COpen
UDP-glucuronosyltransferase 1A9 (UGT1A9)variant M33VHomo sapienssulfinpyrazone—0.039—pH 7.4, 37 °COpen