Values CatLog read from this paper
Kinetic analysis of the effects of monovalent cations and divalent metals on the activity of Mycobacterium tuberculosis alpha-isopropylmalate synthase
PMID 16684501doi:10.1016/j.abb.2006.03.030Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (25 values) from this paper: α-isopropylmalate synthase (MtIPMS) from Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| α-isopropylmalate synthase (MtIPMS) | Mycobacterium tuberculosis | Acetyl Coenzyme ATable 4 monovalent-cation block: Me+ = K+ (saturating) | — | 0.103 | 34 | pH 7.4, 25 °C | Open record: α-isopropylmalate synthase (MtIPMS), Acetyl Coenzyme A |
| α-isopropylmalate synthase (MtIPMS) | Mycobacterium tuberculosis | Acetyl Coenzyme ATable 4 monovalent-cation block: Me+ = Rb+ (saturating) | — | 0.12 | 28 | pH 7.4, 25 °C | Open record: α-isopropylmalate synthase (MtIPMS), Acetyl Coenzyme A |
| α-isopropylmalate synthase (MtIPMS) | Mycobacterium tuberculosis | Acetyl Coenzyme ATable 4 divalent-metal block: Me2+ = Mg2+ (saturating) | — | 0.138 | 15 | pH 7.4, 25 °C | Open record: α-isopropylmalate synthase (MtIPMS), Acetyl Coenzyme A |
| α-isopropylmalate synthase (MtIPMS) | Mycobacterium tuberculosis | Acetyl Coenzyme ATable 4 divalent-metal block: Me2+ = Mn2+ (saturating) | — | 0.05 | 34 | pH 7.4, 25 °C | Open record: α-isopropylmalate synthase (MtIPMS), Acetyl Coenzyme A |
| α-isopropylmalate synthase (MtIPMS) | Mycobacterium tuberculosis | Acetyl Coenzyme ATable 4 divalent-metal block: Me2+ = Co2+ (saturating) | — | 0.037 | 25 | pH 7.4, 25 °C | Open record: α-isopropylmalate synthase (MtIPMS), Acetyl Coenzyme A |
| α-isopropylmalate synthase (MtIPMS) | Mycobacterium tuberculosis | α-ketoisovalerateTable 4 monovalent-cation block: Me+ = K+ (saturating) | 3.2 | 0.016 | 210 | pH 7.4, 25 °C | Open record: α-isopropylmalate synthase (MtIPMS), α-ketoisovalerate |
| α-isopropylmalate synthase (MtIPMS) | Mycobacterium tuberculosis | α-ketoisovalerateTable 4 monovalent-cation block: Me+ = Rb+ (saturating) | 2.9 | 0.019 | 150 | pH 7.4, 25 °C | Open record: α-isopropylmalate synthase (MtIPMS), α-ketoisovalerate |
| α-isopropylmalate synthase (MtIPMS) | Mycobacterium tuberculosis | α-ketoisovalerateTable 4 divalent-metal block: Me2+ = Mg2+ (saturating) | 3.5 | 0.012 | 3.4 × 10³ | pH 7.4, 25 °C | Open record: α-isopropylmalate synthase (MtIPMS), α-ketoisovalerate |
| α-isopropylmalate synthase (MtIPMS) | Mycobacterium tuberculosis | α-ketoisovalerateTable 4 divalent-metal block: Me2+ = Mn2+ (saturating) | 1.69 | 0.0017 | 720 | pH 7.4, 25 °C | Open record: α-isopropylmalate synthase (MtIPMS), α-ketoisovalerate |
| α-isopropylmalate synthase (MtIPMS) | Mycobacterium tuberculosis | α-ketoisovalerateTable 4 divalent-metal block: Me2+ = Co2+ (saturating) | 0.77 | 0.0022 | 350 | pH 7.4, 25 °C | Open record: α-isopropylmalate synthase (MtIPMS), α-ketoisovalerate |