Values CatLog read from this paper
Systematic exploration of active site mutations on human deoxycytidine kinase substrate specificity
PMID 18361501doi:10.1021/bi800157eOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 44 records (132 values) from this paper: deoxycytidine kinase (dCK) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| deoxycytidine kinase (dCK) | Homo sapiens | 2'-deoxyadenosine | 3.1 | 0.081 | 38 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK), 2'-deoxyadenosine |
| deoxycytidine kinase (dCK) | Homo sapiens | 2'-deoxycytidine | 0.064 | 0.001 | 63 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK), 2'-deoxycytidine |
| deoxycytidine kinase (dCK) | Homo sapiens | 2'-deoxyguanosine | 3.26 | 0.154 | 21 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK), 2'-deoxyguanosine |
| deoxycytidine kinase (dCK) | Homo sapiens | thymidine | 0.38 | 3.485 | 0.095 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK), thymidine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133A | Homo sapiens | 2'-deoxyadenosine | 3.4 | 0.598 | 6 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133A, 2'-deoxyadenosine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133A | Homo sapiens | 2'-deoxycytidine | 1.2 | 0.00154 | 777 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133A, 2'-deoxycytidine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133A | Homo sapiens | 2'-deoxyguanosine | 0.31 | 1.364 | 0.23 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133A, 2'-deoxyguanosine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133A | Homo sapiens | thymidine | 3.29 | 0.0314 | 105 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133A, thymidine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133S | Homo sapiens | 2'-deoxyadenosine | 3.37 | 0.843 | 4 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133S, 2'-deoxyadenosine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133S | Homo sapiens | 2'-deoxycytidine | 2.1 | 0.00525 | 400 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133S, 2'-deoxycytidine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133S | Homo sapiens | 2'-deoxyguanosine | 1.72 | 0.739 | 2 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133S, 2'-deoxyguanosine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133S | Homo sapiens | thymidine | 1.91 | 0.00558 | 342 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133S, thymidine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133T | Homo sapiens | 2'-deoxyadenosine | 2.67 | 1.437 | 2 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133T, 2'-deoxyadenosine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133T | Homo sapiens | 2'-deoxycytidine | 3.54 | 0.071 | 50 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133T, 2'-deoxycytidine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133T | Homo sapiens | 2'-deoxyguanosine | 2.29 | 1.164 | 2 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133T, 2'-deoxyguanosine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133T | Homo sapiens | thymidine | 1.57 | 0.00388 | 406 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133T, thymidine |
| deoxycytidine kinase (dCK)variant D47E/R104Q/D133G/N163I/F242L | Homo sapiens | 2'-deoxyadenosine | 1.08 | 0.091 | 12 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant D47E/R104Q/D133G/N163I/F242L, 2'-deoxyadenosine |
| deoxycytidine kinase (dCK)variant D47E/R104Q/D133G/N163I/F242L | Homo sapiens | 2'-deoxycytidine | 0.21 | 0.00141 | 150 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant D47E/R104Q/D133G/N163I/F242L, 2'-deoxycytidine |
| deoxycytidine kinase (dCK)variant D47E/R104Q/D133G/N163I/F242L | Homo sapiens | 2'-deoxyguanosine | 1.18 | 0.079 | 15 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant D47E/R104Q/D133G/N163I/F242L, 2'-deoxyguanosine |
| deoxycytidine kinase (dCK)variant D47E/R104Q/D133G/N163I/F242L | Homo sapiens | thymidine | 0.68 | 0.025 | 27 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant D47E/R104Q/D133G/N163I/F242L, thymidine |
| deoxycytidine kinase (dCK)variant R104M/D133A | Homo sapiens | 2'-deoxyadenosine | 2.71 | 0.412 | 7 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133A, 2'-deoxyadenosine |
| deoxycytidine kinase (dCK)variant R104M/D133A | Homo sapiens | 2'-deoxycytidine | 0.58 | 0.002 | 287 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133A, 2'-deoxycytidine |
| deoxycytidine kinase (dCK)variant R104M/D133A | Homo sapiens | 2'-deoxyguanosine | 1.23 | 1.28 | 0.96 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133A, 2'-deoxyguanosine |
| deoxycytidine kinase (dCK)variant R104M/D133A | Homo sapiens | thymidine | 1.88 | 0.074 | 25 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133A, thymidine |
| deoxycytidine kinase (dCK)variant R104M/D133N | Homo sapiens | 2'-deoxyadenosine | 3.47 | 0.452 | 8 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133N, 2'-deoxyadenosine |
| deoxycytidine kinase (dCK)variant R104M/D133N | Homo sapiens | 2'-deoxycytidine | 2.23 | 0.0118 | 189 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133N, 2'-deoxycytidine |
| deoxycytidine kinase (dCK)variant R104M/D133N | Homo sapiens | 2'-deoxyguanosine | 3.59 | 0.324 | 11 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133N, 2'-deoxyguanosine |
| deoxycytidine kinase (dCK)variant R104M/D133N | Homo sapiens | thymidine | 2.27 | 0.0256 | 88 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133N, thymidine |
| deoxycytidine kinase (dCK)variant R104M/D133S | Homo sapiens | 2'-deoxyadenosine | 4.85 | 0.398 | 12 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133S, 2'-deoxyadenosine |
| deoxycytidine kinase (dCK)variant R104M/D133S | Homo sapiens | 2'-deoxycytidine | 1.7 | 0.00455 | 373 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133S, 2'-deoxycytidine |
| deoxycytidine kinase (dCK)variant R104M/D133S | Homo sapiens | 2'-deoxyguanosine | 4.38 | 1.174 | 4 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133S, 2'-deoxyguanosine |
| deoxycytidine kinase (dCK)variant R104M/D133S | Homo sapiens | thymidine | 2.33 | 0.0189 | 123 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133S, thymidine |
| deoxycytidine kinase (dCK)variant R104M/D133T | Homo sapiens | 2'-deoxyadenosine | 4.14 | 0.691 | 6 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133T, 2'-deoxyadenosine |
| deoxycytidine kinase (dCK)variant R104M/D133T | Homo sapiens | 2'-deoxycytidine | 2.86 | 0.0209 | 137 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133T, 2'-deoxycytidine |
| deoxycytidine kinase (dCK)variant R104M/D133T | Homo sapiens | 2'-deoxyguanosine | 2.5 | 1.203 | 2 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133T, 2'-deoxyguanosine |
| deoxycytidine kinase (dCK)variant R104M/D133T | Homo sapiens | thymidine | 1.49 | 0.0058 | 258 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant R104M/D133T, thymidine |
| deoxycytidine kinase (dCK)variant R104Q/D133G | Homo sapiens | 2'-deoxyadenosine | 1.75 | 0.231 | 8 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant R104Q/D133G, 2'-deoxyadenosine |
| deoxycytidine kinase (dCK)variant R104Q/D133G | Homo sapiens | 2'-deoxycytidine | 0.37 | 0.00104 | 356 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant R104Q/D133G, 2'-deoxycytidine |
| deoxycytidine kinase (dCK)variant R104Q/D133G | Homo sapiens | 2'-deoxyguanosine | 1.5 | 0.081 | 19 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant R104Q/D133G, 2'-deoxyguanosine |
| deoxycytidine kinase (dCK)variant R104Q/D133G | Homo sapiens | thymidine | 1.01 | 0.0257 | 39 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant R104Q/D133G, thymidine |
| deoxycytidine kinase (dCK)variant R104Q/D133N | Homo sapiens | 2'-deoxyadenosine | 2 | 0.532 | 4 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant R104Q/D133N, 2'-deoxyadenosine |
| deoxycytidine kinase (dCK)variant R104Q/D133N | Homo sapiens | 2'-deoxycytidine | 1.3 | 0.0086 | 152 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant R104Q/D133N, 2'-deoxycytidine |
| deoxycytidine kinase (dCK)variant R104Q/D133N | Homo sapiens | 2'-deoxyguanosine | 1.92 | 0.24 | 8 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant R104Q/D133N, 2'-deoxyguanosine |
| deoxycytidine kinase (dCK)variant R104Q/D133N | Homo sapiens | thymidine | 1.51 | 0.036 | 42 | pH 7.5, 30 °C | Open record: deoxycytidine kinase (dCK) variant R104Q/D133N, thymidine |