Values CatLog read from this paper
Stapled histone H3 tails are super-substrates for lysine methyltransferase SETD7
PMID 41383456doi:10.1039/d5sc08094kOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (24 values) from this paper: SETD7 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) linked between Ala1 and Glu6 | 0.031 | 0.0125 | 2.5 | pH 8, 37 °C | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) linked between Ala1 and Glu6 |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) linked between d-Ala1 and Glu6 | 0.23 | 0.0104 | 22.2 | pH 8, 37 °C | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) linked between d-Ala1 and Glu6 |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) linked between Gly1 and Glu6 | 0.046 | 0.00184 | 25 | pH 8, 37 °C | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) linked between Gly1 and Glu6 |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by beta-Ala, linked to Glu6 | 0.0495 | 0.0177 | 2.8 | pH 8, 37 °C | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by beta-Ala, linked to Glu6 |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by Phe, linked to Glu6 | 0.0493 | 0.0346 | 1.43 | pH 8, 37 °C | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by Phe, linked to Glu6 |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by Val, linked to Glu6 | 0.0423 | 0.0341 | 1.23 | pH 8, 37 °C | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by Val, linked to Glu6 |
| SETD7 | Homo sapiens | linear histone H3 peptide, residues 1-13, ARTKQTARKSTGG | 0.014 | 0.0616 | 0.23 | pH 8, 37 °C | Open record: SETD7, linear histone H3 peptide, residues 1-13, ARTKQTARKSTGG |
| SETD7 | Homo sapiens | stapled histone H3 peptide (residues 1-13) with a triazole linkage between positions 1 and 6 | 0.0598 | 0.0362 | 1.65 | pH 8, 37 °C | Open record: SETD7, stapled histone H3 peptide (residues 1-13) with a triazole linkage between positions 1 and 6 |