EC 2.1.1.364: [histone H3]-lysine4 N-methyltransferase
TransferasesOpen in Browse
CatLog read 12 records for EC 2.1.1.364 from 2 papers, for 1 organism. Names in these papers: SETD7, SET9 (histone H3 Lys-4 methyltransferase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Stapled histone H3 tails are super-substrates for lysine methyltransferase SETD7 | Homo sapiens | 8 |
| Structure and catalytic mechanism of a SET domain protein methyltransferase | Homo sapiens | 4 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| SET9 (histone H3 Lys-4 methyltransferase) | Homo sapiens | histone H3 (calf thymus) | 0.004 | 0.0054 | 0.74 calc. | 37 °C | PMID 12372303 | Open record: SET9 (histone H3 Lys-4 methyltransferase), histone H3 (calf thymus) |
| SET9 (histone H3 Lys-4 methyltransferase) | Homo sapiens | S-adenosyl-L-methionine | 0.004 | 0.006 | 0.67 calc. | 37 °C | PMID 12372303 | Open record: SET9 (histone H3 Lys-4 methyltransferase), S-adenosyl-L-methionine |
| SET9 (histone H3 Lys-4 methyltransferase)variant H293A | Homo sapiens | histone H3 (calf thymus) | 0.005 | 7 × 10⁻⁴ | 7.1 calc. | 37 °C | PMID 12372303 | Open record: SET9 (histone H3 Lys-4 methyltransferase) variant H293A, histone H3 (calf thymus) |
| SET9 (histone H3 Lys-4 methyltransferase)variant H293A | Homo sapiens | S-adenosyl-L-methionine | 0.005 | 0.0156 | 0.32 calc. | 37 °C | PMID 12372303 | Open record: SET9 (histone H3 Lys-4 methyltransferase) variant H293A, S-adenosyl-L-methionine |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) linked between Ala1 and Glu6 | 0.031 | 0.0125 | 2.5 | pH 8, 37 °C | PMID 41383456 | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) linked between Ala1 and Glu6 |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) linked between d-Ala1 and Glu6 | 0.23 | 0.0104 | 22.2 | pH 8, 37 °C | PMID 41383456 | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) linked between d-Ala1 and Glu6 |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) linked between Gly1 and Glu6 | 0.046 | 0.00184 | 25 | pH 8, 37 °C | PMID 41383456 | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) linked between Gly1 and Glu6 |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by beta-Ala, linked to Glu6 | 0.0495 | 0.0177 | 2.8 | pH 8, 37 °C | PMID 41383456 | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by beta-Ala, linked to Glu6 |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by Phe, linked to Glu6 | 0.0493 | 0.0346 | 1.43 | pH 8, 37 °C | PMID 41383456 | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by Phe, linked to Glu6 |
| SETD7 | Homo sapiens | lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by Val, linked to Glu6 | 0.0423 | 0.0341 | 1.23 | pH 8, 37 °C | PMID 41383456 | Open record: SETD7, lactam-stapled histone H3 peptide (residues 1-13) with Ala1 replaced by Val, linked to Glu6 |
| SETD7 | Homo sapiens | linear histone H3 peptide, residues 1-13, ARTKQTARKSTGG | 0.014 | 0.0616 | 0.23 | pH 8, 37 °C | PMID 41383456 | Open record: SETD7, linear histone H3 peptide, residues 1-13, ARTKQTARKSTGG |
| SETD7 | Homo sapiens | stapled histone H3 peptide (residues 1-13) with a triazole linkage between positions 1 and 6 | 0.0598 | 0.0362 | 1.65 | pH 8, 37 °C | PMID 41383456 | Open record: SETD7, stapled histone H3 peptide (residues 1-13) with a triazole linkage between positions 1 and 6 |